{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:39:17Z","timestamp":1790386757826,"version":"4.1.0"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1097\/sla.0b013e31823785f6","type":"journal-article","created":{"date-parts":[[2011,12,2]],"date-time":"2011-12-02T13:38:56Z","timestamp":1322833136000},"page":"70-78","source":"Crossref","is-referenced-by-count":101,"title":["Distribution of Lymph Node Metastases Is an Independent Predictor of Survival for Sigmoid Colon and Rectal Cancer"],"prefix":"10.1097","volume":"255","author":[{"given":"Jung Wook","family":"Huh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeong Rok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210203","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/jnci\/93.8.583","article-title":"Guidelines 2000 for colon and rectal cancer surgery.","volume":"93","author":"Nelson","year":"2001","journal-title":"J Natl Cancer Inst"},{"key":"R4-12-20210203","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1200\/JCO.2007.12.7704","article-title":"Prognostic implications of the distribution of lymph node metastases in rectal cancer after neoadjuvant chemoradiotherapy.","volume":"26","author":"Leibold","year":"2008","journal-title":"J Clin Oncol"},{"key":"R5-12-20210203","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.surg.2005.09.004","article-title":"Distribution of lymph node metastasis is a prognostic index in patients with stage III colon cancer.","volume":"139","author":"Kobayashi","year":"2006","journal-title":"Surgery"},{"key":"R6-12-20210203","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jamcollsurg.2005.03.018","article-title":"Number versus distribution in classifying regional lymph node metastases from colon cancer.","volume":"201","author":"Hida","year":"2005","journal-title":"J Am Coll Surg"},{"key":"R7-12-20210203","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s10350-004-6423-6","article-title":"Impact of the number of negative nodes on disease-free survival in colorectal cancer patients.","volume":"45","author":"Wong","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"R8-12-20210203","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF02237119","article-title":"Accurate lymph-node detection in colorectal specimens resected for cancer is of prognostic significance.","volume":"42","author":"Ratto","year":"1999","journal-title":"Dis Colon Rectum"},{"key":"R9-12-20210203","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1002\/1097-0142(19940415)73:8<2076::AID-CNCR2820730811>3.0.CO;2-6","article-title":"Pathologic determinants of survival associated with colorectal cancer with lymph node metastases. A multivariate analysis of 579 patients.","volume":"73","author":"Newland","year":"1994","journal-title":"Cancer"},{"key":"R10-12-20210203","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.jamcollsurg.2006.02.007","article-title":"Number of lymph node metastases is better predictor of prognosis than level of lymph node metastasis in patients with node-positive colon cancer.","volume":"202","author":"Suzuki","year":"2006","journal-title":"J Am Coll Surg"},{"key":"R11-12-20210203","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/PAS.0b013e3180dc92ab","article-title":"Lymph nodes after preoperative chemoradiotherapy for rectal carcinoma: number, status, and impact on survival.","volume":"32","author":"Rullier","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"R12-12-20210203","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.ijrobp.2004.06.259","article-title":"Impact of preoperative radiation for rectal cancer on subsequent lymph node evaluation: a population-based analysis.","volume":"61","author":"Baxter","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R13-12-20210203","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1245\/s10434-010-0982-7","article-title":"Prognostic value of perineural invasion in patients with stage II colorectal cancer.","volume":"17","author":"Huh","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"R14-12-20210203","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1245\/s10434-009-0424-6","article-title":"Proliferating cell nuclear antigen as a prognostic factor after total mesorectal excision of stage II-III rectal cancer.","volume":"16","author":"Huh","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"R15-12-20210203","first-page":"387","article-title":"Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0 J Surg Oncol.","volume":"100","author":"Huh","year":"2009","journal-title":""},{"key":"R16-12-20210203","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1245\/s10434-010-1015-2","article-title":"Ratio of metastatic to resected lymph nodes as a prognostic factor in node-positive colorectal cancer.","volume":"17","author":"Huh","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"R17-12-20210203","first-page":"705","article-title":"Survival impact of lymph node metastasis in TNM stage III carcinoma of the colon and rectum.","volume":"180","author":"Tang","year":"1995","journal-title":"J Am Coll Surg"},{"key":"R18-12-20210203","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/bjs.5327","article-title":"Survival benefit of high ligation of the inferior mesenteric artery in sigmoid colon or rectal cancer surgery.","volume":"93","author":"Kanemitsu","year":"2006","journal-title":"Br J Surg"},{"key":"R19-12-20210203","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/01.coc.0000214930.78200.4a","article-title":"Clinical and pathologic predictors of locoregional recurrence, distant metastasis, and overall survival in patients treated with chemoradiation and mesorectal excision for rectal cancer.","volume":"29","author":"Das","year":"2006","journal-title":"Am J Clin Oncol"},{"key":"R20-12-20210203","first-page":"1116","article-title":"Sphincter-preserving operations following preoperative chemoradiation: an alternative to abdominoperineal resection for lower rectal cancer World J Surg.","volume":"32","author":"Huh","year":"2008","journal-title":""},{"key":"R21-12-20210203","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1007\/s10350-006-0714-z","article-title":"Indication and benefit of pelvic sidewall dissection for rectal cancer.","volume":"49","author":"Sugihara","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"R22-12-20210203","doi-asserted-by":"crossref","first-page":"9257","DOI":"10.1200\/JCO.2005.02.9231","article-title":"Low rectal cancer: a call for a change of approach in abdominoperineal resection.","volume":"23","author":"Nagtegaal","year":"2005","journal-title":"J Clin Oncol"},{"key":"R23-12-20210203","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1002\/bjs.6739","article-title":"Circumferential resection margin as a prognostic factor in rectal cancer.","volume":"96","author":"Bernstein","year":"2009","journal-title":"Br J Surg"},{"key":"R24-12-20210203","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/00000478-200203000-00009","article-title":"Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit.","volume":"26","author":"Nagtegaal","year":"2002","journal-title":"Am J Surg Pathol"},{"key":"R26-12-20210203","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ejso.2003.12.002","article-title":"The clinicopathological significance of inferior mesenteric lymph node metastasis in colorectal cancer.","volume":"30","author":"Kim","year":"2004","journal-title":"Eur J Surg Oncol"},{"key":"R27-12-20210203","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0002-9610(51)90196-1","article-title":"Influence of lateral spread of cancer of the rectum on radicability of operation and prognosis.","volume":"81","author":"Sauer","year":"1951","journal-title":"Am J Surg"},{"key":"R28-12-20210203","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1002\/1097-0142(195111)4:6<1364::AID-CNCR2820040618>3.0.CO;2-M","article-title":"Abdominopelvic lymphnode dissection in cancer of the rectum and distal colon.","volume":"4","author":"Deddish","year":"1951","journal-title":"Cancer"},{"key":"R29-12-20210203","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0959-8049(02)00046-1","article-title":"Patterns of lymphatic spread in rectal cancer. A topographical analysis on lymph node metastases.","volume":"38","author":"Steup","year":"2002","journal-title":"Eur J Cancer"},{"key":"R30-12-20210203","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/bjs.1800770607","article-title":"High versus low ligation of the inferior mesenteric artery in rectal cancer.","volume":"77","author":"Surtees","year":"1990","journal-title":"Br J Surg"},{"key":"R31-12-20210203","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1097\/00000658-198412000-00010","article-title":"Survival after high or low ligation of the inferior mesenteric artery during curative surgery for rectal cancer.","volume":"200","author":"Pezim","year":"1984","journal-title":"Ann Surg"},{"key":"R32-12-20210203","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1007\/s10350-008-9328-y","article-title":"Level of arterial ligation in rectal cancer surgery: low tie preferred over high tie. A review.","volume":"51","author":"Lange","year":"2008","journal-title":"Dis Colon Rectum"},{"key":"R33-12-20210203","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/BF02055167","article-title":"Effect of high and intermediate ligation on survival and recurrence rates following curative resection of colorectal cancer.","volume":"40","author":"Slanetz","year":"1997","journal-title":"Dis Colon Rectum"},{"key":"R34-12-20210203","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00384-006-0221-7","article-title":"Laser Doppler assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery.","volume":"22","author":"Seike","year":"2007","journal-title":"Int J Colorectal Dis"},{"key":"R35-12-20210203","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000077347","article-title":"Ligation of the inferior mesenteric artery in the surgery of rectal cancer: anatomical considerations.","volume":"21","author":"Nano","year":"2004","journal-title":"Dig Surg"},{"key":"R36-12-20210203","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/bjs.1800790730","article-title":"Flush aortic tie versus selective preservation of the ascending left colic artery in low anterior resection for rectal carcinoma.","volume":"79","author":"Corder","year":"1992","journal-title":"Br J Surg"},{"key":"R37-12-20210203","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1007\/s10350-007-0233-6","article-title":"A diverting stoma is not necessary when performing a handsewn coloanal anastomosis for lower rectal cancer.","volume":"50","author":"Huh","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"R38-12-20210203","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/00000658-199910000-00010","article-title":"Safety and efficacy of low anterior resection for rectal cancer: 681 consecutive cases from a specialty service.","volume":"230","author":"Enker","year":"1999","journal-title":"Ann Surg"},{"key":"R39-12-20210203","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3393\/jksc.2009.25.5.340","article-title":"Analysis of anastomotic leakage after an anterior resection for rectal cancer.","volume":"25","author":"Park","year":"2009","journal-title":"J Korean Soc Coloproctol"},{"key":"R40-12-20210203","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1200\/JCO.2003.05.062","article-title":"Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089.","volume":"21","author":"Le Voyer","year":"2003","journal-title":"J Clin Oncol"},{"key":"R41-12-20210203","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/jnci\/dji020","article-title":"Lymph node evaluation in colorectal cancer patients: a population-based study.","volume":"97","author":"Baxter","year":"2005","journal-title":"J Natl Cancer Inst"},{"key":"R42-12-20210203","first-page":"559","article-title":"Should total number of lymph nodes be used as a quality of care measure for stage III colon cancer Ann Surg.","volume":"249","author":"Wang","year":"2009","journal-title":""},{"key":"R43-12-20210203","first-page":"386","article-title":"The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma.","volume":"85","author":"Haboubi","year":"1992","journal-title":"J R Soc Med"},{"key":"R44-12-20210203","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s10434-001-0150-1","article-title":"Validation of lymphatic mapping in colorectal cancer: in vivo, ex vivo, and laparoscopic techniques.","volume":"8","author":"Wood","year":"2001","journal-title":"Ann Surg Oncol"},{"key":"R45-12-20210203","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s10434-999-0579-1","article-title":"Lymph node size and metastatic infiltration in colon cancer.","volume":"6","author":"Monig","year":"1999","journal-title":"Ann Surg Oncol"}],"container-title":["Annals of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/SLA.0b013e31823785f6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:26:27Z","timestamp":1786047987000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000658-201201000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/sla.0b013e31823785f6","relation":{},"ISSN":["0003-4932"],"issn-type":[{"value":"0003-4932","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}