{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T08:11:15Z","timestamp":1696234275779},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Surgical resection of submucosal tumors (SMTs) in the abdominal esophagus is not standardized. Enucleation may be a minimally invasive option, whereas its oncological validity is not very clear. Moreover, how to treat the esophageal wall defect after enucleation and necessity of additional antireflux procedure are also undetermined.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>In 13 patients with a SMT originating the abdominal esophagus laparoscopic enucleation was performed with preserving the integrity of submucosa. When the muscular layer defect was &lt;4 cm it was directly closed by suturing, whereas it was left open in case the defect was larger. Fundoplication was added when the esophagus was dissected posteriorly or the myotomy was not closed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Tumors were resected en-bloc without rupture in all cases. In 5 patients myotomy was closed, whereas in the remaining 8 it was left open. In 11 patients fundoplication was added (Toupet in 5 and Dor in 6). The patients developed neither regurgitation nor stenosis postoperatively. The histopathologic findings revealed leiomyoma in 9 patients, whereas the other 4 were miscellaneous. The average tumor size was 5.5 cm (range, 2.8 to 8.8). Microscopically surgical margin was negative in all cases.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Laparoscopic enucleation of SMTs in the abdominal esophagus seems to be safe, reproducible operation enabling preservation of function of the lower esophagus and esophagogastric junction. Even when the muscular defect is not approximated additional fundoplication can minimize the risk of postoperative reflux disease.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/sle.0000000000000403","type":"journal-article","created":{"date-parts":[[2017,4,25]],"date-time":"2017-04-25T16:10:29Z","timestamp":1493136629000},"page":"189-193","source":"Crossref","is-referenced-by-count":1,"title":["Minimally Invasive, Organ-preserving Surgery for Large Submucosal Tumors in the Abdominal Esophagus"],"prefix":"10.1097","volume":"27","author":[{"given":"Eiji","family":"Kanehira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Tanida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Kamei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kodai","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20231001","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.athoracsur.2004.08.029","article-title":"Esophageal leiomyoma: a 40-year experience","volume":"79","author":"Mutrie","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"R2-20231001","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jtcvs.2006.10.082","article-title":"Minimally invasive resection of benign esophageal tumors","volume":"134","author":"Kent","year":"2007","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R3-20231001","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.athoracsur.2013.10.030","article-title":"Enucleation of esophageal submucosal tumors: a single institution\u2019s experience","volume":"97","author":"Shin","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"R4-20231001","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1055\/s-0030-1250502","article-title":"Thoracoscopic enucleation of a gastrointestinal stromal tumor of the esophagus","volume":"59","author":"Wang","year":"2011","journal-title":"Thorac Cardiovasc Surg"},{"key":"R5-20231001","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1097\/PAS.0b013e31806ab2c3","article-title":"\u201cSeedling\u201d mesenchymal tumors (gastrointestinal stromal tumors and leiomyomas) are common incidental tumors of the esophagogastric junction","volume":"31","author":"Abraham","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R6-20231001","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.3748\/wjg.v17.i16.2159","article-title":"Enucleation for gastrointestinal stromal tumors at the esophagogastric junction: is this an adequate solution?","volume":"17","author":"Peparini","year":"2011","journal-title":"World J Gastroenterol"},{"key":"R7-20231001","doi-asserted-by":"crossref","first-page":"4374","DOI":"10.3748\/wjg.v16.i35.4374","article-title":"Esophagogastric junction gastrointestinal stromal tumor: resection vs enucleation","volume":"16","author":"Coccolini","year":"2010","journal-title":"World J Gastroenterol"},{"key":"R8-20231001","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/00000658-199301000-00012","article-title":"Lymph node metastasis from soft tissue sarcoma in adults. 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