{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T09:07:05Z","timestamp":1782119225186,"version":"3.54.5"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Biliopancreatic diversion with duodenal switch (BPD-DS) is an effective yet technically challenging bariatric surgery with many complications. Alternatively, single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) was recently introduced as a simplified bariatric procedure. This meta-analysis aimed to assess the safety and efficacy of SADI-S compared with BPD-DS in the management of patients with obesity.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Cochrane, Embase, PubMed, Scopus, and Web of Science were searched for articles from their inception to May 2022 by 2 independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-analysis system. The review was registered prospectively with PROSPERO (CRD42022333521).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>From 123 studies screened, 6 studies met the eligibility criteria, with a total of 1847 patients with obesity undergoing either SADI-S (n=818) or BPD-DS (n=1029). Preoperative body mass index was similar between the 2 groups, and the BPD-DS group had a greater % excess body mass index loss (EBMIL) (MD=\u221210.16%, 95% confidence interval: \u221211.80, \u22128.51, I<jats:sup>2<\/jats:sup>=0%) at 2 years compared with the SADI-S group. There was no difference observed in preoperative comorbidities and remission, including diabetes, hypertension, and dyslipidemia between SADI-S and BPD-DS cohorts. Compared with BPD-DS, SADI-S had shorter hospital stays (MD=\u22121.36\u00a0d, 95% CI: \u22122.39, \u22120.33, I<jats:sup>2<\/jats:sup>=86%), and fewer long-term (&gt;30\u00a0d) complications (OR=0.56, 95% CI: 0.42, 0.74, I<jats:sup>2<\/jats:sup>=20%). Conversely, among nutritional deficiency outcomes, the SADI-S group had few patients with abnormal vitamin D (OR=0.51, 95% CI: 0.36, 0.72, I<jats:sup>2<\/jats:sup>=0%) values than the BPD-DS group.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>SADI-S has shown to be a possible alternative treatment option to BPD-DS in managing patients with obesity. Despite the promising results, further randomized controlled studies with more extended follow-up periods are necessary to ascertain the safety and efficacy of the treatment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/sle.0000000000001102","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T20:00:06Z","timestamp":1663790406000},"page":"595-605","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":23,"title":["Single Versus Double Anastomosis Duodenal Switch in the Management of Obesity: A Meta-analysis and Systematic Review"],"prefix":"10.1097","volume":"32","author":[{"given":"Hayato","family":"Nakanishi","sequence":"first","affiliation":[{"name":"St George\u2019s University of London, London, UK"},{"name":"University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reem H.","family":"Matar","sequence":"additional","affiliation":[{"name":"St George\u2019s University of London, London, UK"},{"name":"University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus"},{"name":"Department of Gastroenterology and Hepatology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Vahibe","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic. 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Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Clapp","sequence":"additional","affiliation":[{"name":"Department of Surgery, Texas Tech HSC Paul Foster School of Medicine. El Paso, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar M.","family":"Ghanem","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic. 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