{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:29:16Z","timestamp":1791109756882,"version":"4.1.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1097\/spc.0b013e3282ef5e74","type":"journal-article","created":{"date-parts":[[2008,5,4]],"date-time":"2008-05-04T04:01:43Z","timestamp":1209873703000},"page":"102-108","source":"Crossref","is-referenced-by-count":16,"title":["Mechanisms of dyspnea in chronic lung disease"],"prefix":"10.1097","volume":"1","author":[{"given":"Laura K","family":"Rock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M","family":"Schwartzstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210126","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1164\/ajrccm.159.1.ats898","article-title":"Mechanisms, assessment, and management: a consensus statement. American Thoracic Society.","volume":"159","year":"1999","journal-title":"J Respir Crit Care Med"},{"key":"R2-4-20210126","first-page":"93","article-title":"Mechanisms of dyspnea","author":"Gillette","year":"2005"},{"key":"R3-4-20210126","first-page":"29","article-title":"Mechanisms of dyspnea in COPD","author":"O'Donnell","year":"2005"},{"key":"R4-4-20210126","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1056\/NEJM199512073332307","article-title":"Pathophysiology of dyspnea","volume":"333","author":"Manning","year":"1995","journal-title":"N Engl J Med"},{"key":"R5-4-20210126","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1513\/pats.200508-094DO","article-title":"Why does the lung hyperinflate?","volume":"3","author":"Ferguson","year":"2006","journal-title":"Proc Am Thorac Soc"},{"key":"R6-4-20210126","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1164\/ajrccm.155.1.9001298","article-title":"Qualitative aspects of exertional breathlessness in chronic airflow limitation: pathophysiologic mechanisms","volume":"155","author":"O'Donnell","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"R7-4-20210126","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1513\/pats.200611-159CC","article-title":"Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable","volume":"4","author":"O'Donnell","year":"2007","journal-title":"Proc Am Thorac Soc"},{"key":"R8-4-20210126","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1164\/ajrccm.163.6.2003172","article-title":"Inspiratory capacity, dynamic hyperinflation, breathlessness, and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease","volume":"163","author":"Marin","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"R9-4-20210126","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1378\/chest.126.6.1855","article-title":"Simplified detection of dynamic hyperinflation","volume":"126","author":"Gelb","year":"2004","journal-title":"Chest"},{"key":"R10-4-20210126","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1440-1843.2006.00963.x","article-title":"Effects of bronchodilators on dynamic hyperinflation following hyperventilation in patients with COPD","volume":"12","author":"Fujimoto","year":"2007","journal-title":"Respirology"},{"key":"R11-4-20210126","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1378\/chest.06-1662","article-title":"Tiotropium and simplified detection of dynamic hyperinflation","volume":"131","author":"Gelb","year":"2007","journal-title":"Chest"},{"key":"R12-4-20210126","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1378\/chest.121.4.1042","article-title":"Response of lung volumes to inhaled salbutamol in a large population of patients with severe hyperinflation","volume":"121","author":"Newton","year":"2002","journal-title":"Chest"},{"key":"R13-4-20210126","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1378\/chest.130.3.647","article-title":"Effect of fluticasone propionate\/salmeterol on lung hyperinflation and exercise endurance in COPD","volume":"130","author":"O'Donnell","year":"2006","journal-title":"Chest"},{"key":"R14-4-20210126","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1183\/09031936.04.00116004","article-title":"Effects of tiotropium on lung hyperinflation, dyspnea and exercise tolerance in COPD","volume":"23","author":"O'Donnell","year":"2004","journal-title":"Eur Respir J"},{"key":"R15-4-20210126","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1164\/rccm.200504-595OC","article-title":"Lung mechanics and dyspnea during exacerbations of chronic obstructive pulmonary disease","volume":"172","author":"Stevenson","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"R16-4-20210126","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1152\/japplphysiol.01470.2005","article-title":"Sensory-mechanical relationships during high-intensity, constant-work-rate exercise in COPD","volume":"101","author":"O'Donnell","year":"2006","journal-title":"J Appl Physiol"},{"key":"R17-4-20210126","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0885-3924(01)00367-0","article-title":"Nebulized furosemide as a novel treatment for dyspnea in terminal cancer patients","volume":"23","author":"Shimoyama","year":"2002","journal-title":"J Pain Symptom Manage"},{"key":"R18-4-20210126","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S0885-3924(03)00322-1","article-title":"Effect of nebulized furosemide in terminally ill cancer patients with dyspnea","volume":"26","author":"Kohara","year":"2003","journal-title":"J Pain Symptom Manage"},{"key":"R19-4-20210126","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1177\/026921639400800315","article-title":"Nebulized frusemide for dyspnea","volume":"8","author":"Stone","year":"1994","journal-title":"Palliat Med"},{"issue":"3","key":"R20-4-20210126","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1164\/ajrccm.162.3.2001001","article-title":"Responses of tracheobronchial receptors to inhaled furosemide in anesthetized rats","volume":"162","author":"Sudo","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"R21-4-20210126","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1164\/ajrccm.161.6.9910009","article-title":"Inhaled furosemide greatly alleviates the sensation of experimentally induced dyspnea","volume":"161","author":"Nishino","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"R22-4-20210126","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1164\/rccm.200308-1171OC","article-title":"Effects of inhaled furosemide on exertional dyspnea in chronic obstructive pulmonary disease","volume":"169","author":"Ong","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"R23-4-20210126","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.resp.2006.07.004","article-title":"Effect of inhaled furosemide on air hunger induced in healthy humans","volume":"156","author":"Moosavi","year":"2007","journal-title":"Respir Physiol Neurobiol"},{"key":"R24-4-20210126","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0034-5687(92)90131-F","article-title":"Reduced tidal volume increases \u2018air hunger\u2019 at fixed PCO2 in ventilated quadriplegics","volume":"90","author":"Manning","year":"1992","journal-title":"Respir Physiol"},{"key":"R25-4-20210126","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1164\/ajrccm.162.3.9909112","article-title":"Symptom perception and respiratory sensation in asthma","volume":"162","author":"Banzett","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"R26-4-20210126","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1159\/000095910","article-title":"Sensory and affective aspects of dyspnea contribute differentially to the Borg scale's measurement of dyspnea","volume":"73","author":"von Leupoldt","year":"2006","journal-title":"Respiration"},{"key":"R27-4-20210126","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.rmed.2006.06.033","article-title":"Attentional distraction reduces the affective but not the sensory dimension of perceived dyspnea","volume":"101","author":"von Leupoldt","year":"2007","journal-title":"Respir Med"},{"key":"R28-4-20210126","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00006199-200001000-00003","article-title":"Influence of attention and judgement on perception of breathlessness in healthy individuals and patients with chronic obstructive pulmonary disease","volume":"49","author":"Meek","year":"2000","journal-title":"Nurs Res"},{"key":"R29-4-20210126","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1378\/chest.107.5.1213","article-title":"Effect of distractive auditory stimuli on exercise tolerance in patients with COPD","volume":"107","author":"Thornby","year":"1995","journal-title":"Chest"},{"key":"R30-4-20210126","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/j.2048-7940.2003.tb02059.x","article-title":"Evaluating the effects of music on dyspnea during exercise in individuals with chronic obstructive pulmonary disease: a pilot study","volume":"28","author":"Brooks","year":"2003","journal-title":"Rehabil Nurs"},{"key":"R31-4-20210126","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1097\/00008483-199805000-00007","article-title":"Effects of music on exercise and perceived symptoms in patients with chronic obstructive pulmonary disease","volume":"18","author":"Pfister","year":"1998","journal-title":"J Cardiopulm Rehabil"},{"key":"R32-4-20210126","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1469-8986.2006.00415.x","article-title":"The impact of emotions on the sensory and affective dimension of perceived dyspnea","volume":"43","author":"Von Leupoldt","year":"2006","journal-title":"Psychophysiology"},{"key":"R33-4-20210126","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1034\/j.1399-3003.1999.13d09.x","article-title":"Asthma symptoms: influence of personality versus clinical status","volume":"13","author":"Put","year":"1999","journal-title":"Eur Respir J"},{"key":"R34-4-20210126","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.jpsychores.2004.12.005","article-title":"Accuracy of respiratory symptom perception in different affective contexts","volume":"58","author":"Bogaerts","year":"2005","journal-title":"J Psychosom Res"}],"container-title":["Current Opinion in Supportive & Palliative Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/SPC.0b013e3282ef5e74","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:59:57Z","timestamp":1786035597000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01263393-200708000-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/spc.0b013e3282ef5e74","relation":{},"ISSN":["1751-4258"],"issn-type":[{"value":"1751-4258","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}