{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:01:04Z","timestamp":1790834464708,"version":"4.1.0"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1097\/ta.0b013e318184ba72","type":"journal-article","created":{"date-parts":[[2008,10,6]],"date-time":"2008-10-06T07:09:48Z","timestamp":1223276988000},"page":"901-909","source":"Crossref","is-referenced-by-count":16,"title":["Ketamine-Based Total Intravenous Anesthesia Versus Isoflurane Anesthesia in a Swine Model of Hemorrhagic Shock"],"prefix":"10.1097","volume":"65","author":[{"given":"Michael S.","family":"Englehart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie E.","family":"Allison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon H.","family":"Tieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laszlo N.","family":"Kiraly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha A.","family":"Underwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Muller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome A.","family":"Differding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca S.","family":"Sawai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayhan","family":"Karahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin A.","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-26-20210211","article-title":"Reducing the Burden of Injury: Advancing Prevention and Treatment.","year":"1999"},{"key":"R2-26-20210211","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00005373-199502000-00006","article-title":"Epidemiology of trauma deaths: A reassessment.","volume":"38","author":"Sauaia","year":"1995","journal-title":"J Trauma"},{"key":"R3-26-20210211","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00003246-197603000-00002","article-title":"Fluid resuscitation following injury: rational for the use of balanced salt solutions.","volume":"4","author":"Carrico","year":"1976","journal-title":"Crit Care Med"},{"key":"R4-26-20210211","first-page":"434","article-title":"Colloid or crystalloid in the resuscitation of hemorrhagic shock: a controlled clinical trial.","volume":"89","author":"Moss","year":"1981","journal-title":"Surgery"},{"key":"R5-26-20210211","first-page":"87","article-title":"Advanced Trauma Life Support Course for Doctors.","year":"1997"},{"key":"R6-26-20210211","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/00000542-198512000-00018","article-title":"Halothane anesthesia attenuates cardiopulmonary baroreflex control of peripheral resistance in humans.","volume":"63","author":"Ebert","year":"1985","journal-title":"Anesthesiology"},{"key":"R7-26-20210211","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/BF03005103","article-title":"The effects of isoflurane on arterial pressure, pulse rate, autonomic nervous activity, and barostatic reflexes.","volume":"24","author":"Skovsted","year":"1977","journal-title":"Can Anaesth Soc J"},{"key":"R8-26-20210211","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1097\/00000542-197311000-00003","article-title":"Inotropic effects of isoflurane on mechanics of contraction in isolated cat papillary muscles from normal and failing hearts.","volume":"39","author":"Kemmotsu","year":"1973","journal-title":"Anesthesiology"},{"key":"R9-26-20210211","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/01.ta.0000224211.36154.44","article-title":"Fluid resuscitation increases inflammatory gene transcription following traumatic injury.","volume":"61","author":"Watters","year":"2006","journal-title":"J Trauma"},{"key":"R10-26-20210211","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1365-2044.1974.tb00583.x","article-title":"Ketamine and pancuronium for the shocked patient.","volume":"29","author":"Bond","year":"1974","journal-title":"Anesthesia"},{"key":"R11-26-20210211","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/j.1365-2044.1975.tb00921.x","article-title":"A Technique of anesthesia in haemorrhagic shock. Illustrative case histories and a discussion.","volume":"30","author":"McGown","year":"1975","journal-title":"Anaesthesia"},{"key":"R12-26-20210211","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1365-2044.1980.tb05098.x","article-title":"Total intravenous anaesthesia: a technique using flunitrazepam, ketamine, muscle relaxant and controlled ventilation of the lung.","volume":"35","author":"Barclay","year":"1980","journal-title":"Anaesthesia"},{"key":"R13-26-20210211","first-page":"533","article-title":"Total intravenous anesthesia for military surgery. A technique using ketamine, midazolam, and vecuronium.","volume":"44","author":"Restall","year":"1989","journal-title":"Anaesthesia"},{"key":"R14-26-20210211","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1136\/jramc-151-04-09","article-title":"Anaesthesia in austere environments.","volume":"151","author":"Mellor","year":"2005","journal-title":"J R Army Med Corps"},{"key":"R15-26-20210211","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/00000542-198202000-00007","article-title":"Ketamine: its pharmacology and therapeutic uses.","volume":"56","author":"White","year":"1982","journal-title":"Anesthesiology"},{"key":"R16-26-20210211","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/BF03004864","article-title":"Response to hypercapnia under ketamine anesthesia.","volume":"22","author":"Soliman","year":"1975","journal-title":"Can Anesth Soc J"},{"key":"R17-26-20210211","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1097\/00000542-197212000-00008","article-title":"Circulatory Responses to ketamine anesthesia.","volume":"37","author":"Tweed","year":"1972","journal-title":"Anesthesiology"},{"key":"R18-26-20210211","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF03004579","article-title":"An experimental study of the mechanisms of action of ketamine on the central nervous system.","volume":"21","author":"Wong","year":"1974","journal-title":"Can Anesth Soc J"},{"key":"R19-26-20210211","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1213\/00000539-197150050-00010","article-title":"The effect of \u03b1-adrenergic blockade on the cardiopulmonary response to ketamine.","volume":"50","author":"Traber","year":"1971","journal-title":"Anesth Analg"},{"key":"R20-26-20210211","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/00000542-200108000-00030","article-title":"Mechanisms of direct inhibitory action of ketamine on vascular smooth muscle in mesenteric resistance arteries.","volume":"95","author":"Akata","year":"2001","journal-title":"Anesthesiology"},{"key":"R21-26-20210211","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2165\/00003495-199700543-00007","article-title":"Endothelial dysfunction and atherothrombotic occlusive disease.","volume":"54","author":"Freedman","year":"1997","journal-title":"Drugs"},{"key":"R22-26-20210211","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1097\/01.CCM.0000163246.33366.51","article-title":"Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells by downregulating endothelial nitric oxide synthase expression and intracellular calcium levels.","volume":"33","author":"Chen","year":"2005","journal-title":"Crit Care Med"},{"key":"R23-26-20210211","first-page":"1122","article-title":"Cerebral blood flow is not altered in sheep with pseudomonas sepsis treated with norepinephrine or nitric oxide synthase inhibition.","volume":"96","author":"Booke","year":"2003","journal-title":"Anesth Analg"},{"key":"R24-26-20210211","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.0001-5172.2004.0312.x","article-title":"Ketamine suppresses endotoxin-induced NF-\u03baB activation and cytokine production in the intestine.","volume":"48","author":"Sun","year":"2004","journal-title":"Acta Anaesthesiol Scand"},{"key":"R25-26-20210211","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.3748\/wjg.v10.i7.1028","article-title":"Ketamine suppresses Intestinal NF-kappa B activation and proinflammatory cytokine in endotoxic rats.","volume":"10","author":"Sun","year":"2004","journal-title":"World J Gastroenterol"},{"key":"R26-26-20210211","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/bja\/77.2.238","article-title":"Ketamine inhibits nitric oxide production in mouse-activated macrophage-like cells.","volume":"77","author":"Shimaoka","year":"1996","journal-title":"Br J Anaesth"},{"key":"R27-26-20210211","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1213\/00000539-199909000-00024","article-title":"Ketamine suppresses proinflammatory cytokine production in human whole blood in vitro.","volume":"89","author":"Kawasaki","year":"1999","journal-title":"Anesth Analg"},{"key":"R28-26-20210211","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1097\/00003246-199512000-00009","article-title":"Ketamine attenuates enodtoxin-induced leukocyte adherence in rat mesenteric venules.","volume":"23","author":"Schmidt","year":"1995","journal-title":"Crit Care Med"},{"key":"R29-26-20210211","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1097\/00003246-199809000-00022","article-title":"Ketamine significantly reduces the migration of leukocytes through endothelial cell monolayers.","volume":"26","author":"Hofbauer","year":"1998","journal-title":"Crit Care Med"},{"key":"R30-26-20210211","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1034\/j.1399-6576.1999.431007.x","article-title":"Ketamine does not inhibit inflammatory responses of cultured human endothelial cells but reduces chemotactic activation of neutrophils.","volume":"43","author":"Zahler","year":"1999","journal-title":"Acat Anaesthesiol Scand"},{"key":"R31-26-20210211","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.burns.2004.01.006","article-title":"Ketamine reduces mortality of severely burnt rats, when compared to midazolam plus fentanyl.","volume":"30","author":"Neder Meyer","year":"2004","journal-title":"Burns"},{"key":"R32-26-20210211","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/00005373-200208000-00011","article-title":"The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries.","volume":"53","author":"Schreiber","year":"2002","journal-title":"J Trauma"},{"key":"R34-26-20210211","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/1043-4666(91)90494-X","article-title":"Molecular cloning and sequence of porcine interleukin 6 cDNA and expression of mRNA in synovial fibroblasts in vitro.","volume":"3","author":"Richards","year":"1991","journal-title":"Cytokine"},{"key":"R36-26-20210211","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/10495399109525752","article-title":"Complete nucleotide sequence of a cDNA encoding porcine tumor necrosis factor-alpha.","volume":"2","author":"Choi","year":"1991","journal-title":"Anim Biotechnol"},{"key":"R37-26-20210211","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S1072-7515(02)01835-5","article-title":"The effect of recombinant factor VIIa on noncoagulopathic pigs with grade V liver injuries.","volume":"196","author":"Schreiber","year":"2003","journal-title":"J Am Coll Surg"},{"key":"R38-26-20210211","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1097\/01.shk.0000135288.54535.8a","article-title":"Resuscitation with lactated ringer\u2019s does not increase inflammatory response in a swine model of uncontrolled hemorrhagic shock.","volume":"22","author":"Watters","year":"2004","journal-title":"Shock"},{"key":"R39-26-20210211","first-page":"89","article-title":"Hextend attenuates hypercoagulability following severe injury in swine.","volume":"9","author":"Todd","year":"2005","journal-title":"J Trauma"},{"key":"R40-26-20210211","first-page":"7","article-title":"Resuscitation with normal saline (NS) vs. lactated ringers modulates hypercoagulability and leads to increased blood loss in an uncontrolled hemorrhagic shock swine model.","volume":"1","author":"Kiraly","year":"2006","journal-title":"J Trauma"},{"key":"R41-26-20210211","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/01.ta.0000222723.54559.47","article-title":"A single bolus of 3% hypertonic saline with 6% dextran provides optimal initial resuscitation after uncontrolled hemorrhagic shock.","volume":"61","author":"Watters","year":"2006","journal-title":"J Trauma"},{"key":"R42-26-20210211","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/01.ta.0000224211.36154.44","article-title":"Fluid resuscitation increases inflammatory gene transcription following traumatic injury.","volume":"61","author":"Watters","year":"2006","journal-title":"J Trauma"},{"key":"R43-26-20210211","first-page":"636","article-title":"Lactated ringer\u2019s is superior to normal saline in the resuscitation of uncontrolled hemorrhagic shock.","volume":"62","author":"Todd","year":"2007","journal-title":"J Trauma"},{"key":"R44-26-20210211","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00024382-200206000-00003","article-title":"Base deficit does not predict mortality when secondary to hyperchloremic acidosis.","volume":"17","author":"Brill","year":"2002","journal-title":"Shock"},{"key":"R45-26-20210211","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/00000542-198312000-00005","article-title":"Effects of isoflurane on the baroreceptor reflex.","volume":"59","author":"Seagard","year":"1983","journal-title":"Anesthesiology"},{"key":"R46-26-20210211","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1177\/106002808301700601","article-title":"Comparative effects and analgesic efficacy of the agonist-antagonist opioids.","volume":"17","author":"Zola","year":"1983","journal-title":"Drug Intell Clin Pharm"},{"key":"R47-26-20210211","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1213\/00000539-198209000-00011","article-title":"Comparative cardiovascular effects of midazolam and thiopental in healthy patients.","volume":"61","author":"Lebowitz","year":"1982","journal-title":"Anesth Analg"}],"container-title":["Journal of Trauma: Injury, Infection & Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/TA.0b013e318184ba72","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T20:38:24Z","timestamp":1631911104000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00005373-200810000-00026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/ta.0b013e318184ba72","relation":{},"ISSN":["0022-5282"],"issn-type":[{"value":"0022-5282","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}