{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:09:48Z","timestamp":1786118988540,"version":"build-2736575974"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1097\/ta.0b013e318184ee35","type":"journal-article","created":{"date-parts":[[2008,12,3]],"date-time":"2008-12-03T03:43:37Z","timestamp":1228275817000},"page":"1511-1519","source":"Crossref","is-referenced-by-count":12,"title":["Inflammation and the Host Response to Injury, a Large-Scale Collaborative Project: Patient-Oriented Research Core\u2014Standard Operating Procedures for Clinical Care VII\u2014Guidelines for Antibiotic Administration in Severely Injured Patients"],"prefix":"10.1097","volume":"65","author":[{"given":"Michael A.","family":"West","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest E.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avery B.","family":"Nathens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Cuschieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian G.","family":"Harbrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P.","family":"Minei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Bankey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald V.","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-50-20210211","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s11910-006-0056-1","article-title":"Nosocomial infections in neurocritical care.","volume":"6","author":"Ortiz","year":"2006","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"Suppl 2","key":"R2-50-20210211","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1016\/j.injury.2006.04.012","article-title":"Antibiotics in trauma and orthopedic surgery\u2014a primer of evidence-based recommendations.","volume":"37","author":"Jaeger","year":"2006","journal-title":"Injury"},{"key":"R3-50-20210211","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1086\/510393","article-title":"Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship.","volume":"44","author":"Dellit","year":"2007","journal-title":"Clin Infect Dis"},{"key":"R4-50-20210211","first-page":"69","article-title":"The implications of enterococci for the intensive care unit.","volume":"9","author":"Chatterjee","year":"2007","journal-title":"Crit Care Resusc"},{"key":"R5-50-20210211","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/109629604773860273","article-title":"Nosocomial infections adversely affect the outcomes of patients with serious intraabdominal infections.","volume":"5","author":"Merlino","year":"2004","journal-title":"Surg Infect (Larchmt)"},{"key":"R6-50-20210211","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1089\/sur.2005.6.283","article-title":"Antimicrobial management of complicated skin and skin structure infections in the era of emerging resistance.","volume":"6","author":"Lee","year":"2005","journal-title":"Surg Infect (Larchmt)"},{"key":"R7-50-20210211","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1067\/mic.2001.114225","article-title":"Antibiotic-resistant organisms among long-term care facility residents on admission to an inpatient geriatrics unit: retrospective and prospective surveillance.","volume":"29","author":"Mylotte","year":"2001","journal-title":"Am J Infect Control"},{"key":"R8-50-20210211","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1089\/109629600321137","article-title":"Coverage of enterococci in community acquired secondary peritonitis: results of a randomized trial.","volume":"1","author":"Rohrborn","year":"2000","journal-title":"Surg Infect"},{"key":"R9-50-20210211","first-page":"122","article-title":"Clinical and scientific importance of source control in abdominal infections: summary of a symposium.","volume":"42","author":"Bohnen","year":"1999","journal-title":"Can J Surg"},{"issue":"11 Suppl","key":"R10-50-20210211","doi-asserted-by":"crossref","first-page":"S513","DOI":"10.1097\/01.CCM.0000143119.41916.5D","article-title":"Source control in the management of severe sepsis and septic shock: an evidence-based review.","volume":"32","author":"Marshall","year":"2004","journal-title":"Crit Care Med"},{"key":"R11-50-20210211","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.micinf.2004.05.017","article-title":"Intra-abdominal infections.","volume":"6","author":"Marshall","year":"2004","journal-title":"Microbes Infect"},{"key":"R12-50-20210211","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/00075198-200110000-00009","article-title":"Recent developments in clinical management of surgical sepsis.","volume":"7","author":"Danielson","year":"2001","journal-title":"Curr Opin Crit Care"},{"key":"R13-50-20210211","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/01.CCM.0000298158.12101.41","article-title":"Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.","volume":"36","author":"Dellinger","year":"2008","journal-title":"Crit Care Med"},{"key":"R15-50-20210211","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/01.CCM.0000055381.70829.94","article-title":"Treatment of ventilator-associated pneumonia: get it right from the start.","volume":"31","author":"Kollef","year":"2003","journal-title":"Crit Care Med"},{"key":"R16-50-20210211","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","article-title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP\/SCCM Consensus Conference Committee. American College of Chest Physicians\/Society of Critical Care Medicine.","volume":"101","author":"Bone","year":"1992","journal-title":"Chest"},{"key":"R17-50-20210211","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1097\/00003246-199711000-00014","article-title":"American College of Chest Physicians\/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients.","volume":"25","author":"Muckart","year":"1997","journal-title":"Crit Care Med"},{"key":"R18-50-20210211","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00134-005-0039-8","article-title":"An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence in Acutely Ill Patients (SOAP) study.","volume":"32","author":"Sprung","year":"2006","journal-title":"Intensive Care Med"},{"issue":"11 Suppl","key":"R19-50-20210211","doi-asserted-by":"crossref","first-page":"S466","DOI":"10.1097\/01.CCM.0000145917.89975.F5","article-title":"Diagnosis of infection in sepsis: an evidence-based review.","volume":"32","author":"Cohen","year":"2004","journal-title":"Crit Care Med"},{"key":"R20-50-20210211","first-page":"39","article-title":"Management of infection in the surgical patient: an update.","volume":"11","author":"McGilvray","year":"2003","journal-title":"Surg Technol Int"},{"issue":"11 Suppl","key":"R22-50-20210211","doi-asserted-by":"crossref","first-page":"S495","DOI":"10.1097\/01.CCM.0000143118.41100.14","article-title":"Antimicrobial therapy for patients with severe sepsis and septic shock: an evidence-based review.","volume":"32","author":"Bochud","year":"2004","journal-title":"Crit Care Med"},{"key":"R23-50-20210211","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/01.sla.0000230024.84190.a8","article-title":"Randomized controlled trial of moxifloxacin compared with piperacillin-tazobactam and amoxicillin-clavulanate for the treatment of complicated intra-abdominal infections.","volume":"244","author":"Malangoni","year":"2006","journal-title":"Ann Surg"},{"issue":"Suppl 5","key":"R24-50-20210211","doi-asserted-by":"crossref","first-page":"S315","DOI":"10.1086\/431673","article-title":"In vitro activity of tigecycline against isolates from patients enrolled in phase 3 clinical trials of treatment for complicated skin and skin-structure infections and complicated intra-abdominal infections.","volume":"41","author":"Bradford","year":"2005","journal-title":"Clin Infect Dis"},{"key":"R25-50-20210211","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1001\/archsurg.1978.01370190075013","article-title":"A review. Lessons from an animal model of intra-abdominal sepsis.","volume":"113","author":"Bartlett","year":"1978","journal-title":"Arch Surg"},{"key":"R26-50-20210211","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/00000658-199111000-00001","article-title":"Antibiotic treatment for surgical peritonitis.","volume":"214","author":"Mosdell","year":"1991","journal-title":"Ann Surg"},{"key":"R27-50-20210211","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1089\/109629602761624171","article-title":"The Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-Abdominal Infections: an executive summary.","volume":"3","author":"Mazuski","year":"2002","journal-title":"Surg Infect"},{"key":"R28-50-20210211","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1086\/378702","article-title":"Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections.","volume":"37","author":"Solomkin","year":"2003","journal-title":"Clin Infect Dis"},{"key":"R29-50-20210211","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1055\/s-2003-44848","article-title":"Hospital-acquired infections in the surgical intensive care: epidemiology and prevention.","volume":"128","author":"Smith","year":"2003","journal-title":"Zentralbl Chir"},{"issue":"5 Suppl 2","key":"R30-50-20210211","doi-asserted-by":"crossref","first-page":"583S","DOI":"10.1016\/S0012-3692(15)31064-3","article-title":"Ventilator-associated pneumonia: insights from recent clinical trials.","volume":"128","author":"Shorr","year":"2005","journal-title":"Chest"},{"key":"R31-50-20210211","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/01.ccx.0000244126.84989.a2","article-title":"De-escalation therapy in ventilator-associated pneumonia.","volume":"12","author":"Niederman","year":"2006","journal-title":"Curr Opin Crit Care"},{"key":"R32-50-20210211","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1164\/rccm.200405-644ST","article-title":"Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia.","volume":"171","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"R33-50-20210211","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1001\/jama.290.19.2588","article-title":"Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial.","volume":"290","author":"Chastre","year":"2003","journal-title":"JAMA"},{"key":"R34-50-20210211","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0012-3692(15)33412-7","article-title":"Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.","volume":"124","author":"Wunderink","year":"2003","journal-title":"Chest"},{"key":"R35-50-20210211","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1067\/mic.2002.130032","article-title":"National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2002, issued August 2002.","volume":"30","year":"2002","journal-title":"Am J Infect Control"},{"key":"R36-50-20210211","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/00003246-199905000-00020","article-title":"Nosocomial infections in medical intensive care units in the United States. National Nosocomial Infections Surveillance System.","volume":"27","author":"Richards","year":"1999","journal-title":"Crit Care Med"},{"key":"R37-50-20210211","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.2165\/00003495-200363140-00003","article-title":"A practical guide to the treatment of complicated skin and soft tissue infections.","volume":"63","author":"Fung","year":"2003","journal-title":"Drugs"},{"issue":"Suppl 2","key":"R38-50-20210211","first-page":"ii37","article-title":"Complicated infections of skin and skin structures: when the infection is more than skin deep.","volume":"53","author":"DiNubile","year":"2004","journal-title":"J Antimicrob Chemother"},{"key":"R39-50-20210211","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1086\/320001","article-title":"Guidelines for the management of intravascular catheter-related infections.","volume":"32","author":"Mermel","year":"2001","journal-title":"Clin Infect Dis"},{"key":"R40-50-20210211","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1097\/01.CCM.0000142399.70913.2F","article-title":"Eliminating catheter-related bloodstream infections in the intensive care unit.","volume":"32","author":"Berenholtz","year":"2004","journal-title":"Crit Care Med"},{"key":"R41-50-20210211","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1089\/109629600750067200","article-title":"The diagnostic value of fungal surveillance cultures in critically ill patients.","volume":"1","author":"Pelz","year":"2000","journal-title":"Surg Infect"},{"key":"R42-50-20210211","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1007\/s00134-005-2794-y","article-title":"Prophylaxis of Candida infections in adult trauma and surgical intensive care patients: a systematic review and meta-analysis.","volume":"31","author":"Cruciani","year":"2005","journal-title":"Intensive Care Med"},{"key":"R43-50-20210211","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1097\/00000658-200104000-00010","article-title":"Double-blind placebo-controlled trial of fluconazole to prevent candidal infections in critically ill surgical patients.","volume":"233","author":"Pelz","year":"2001","journal-title":"Ann Surg"}],"container-title":["Journal of Trauma: Injury, Infection & Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/TA.0b013e318184ee35","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:29:50Z","timestamp":1786037390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005373-200812000-00050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/ta.0b013e318184ee35","relation":{},"ISSN":["0022-5282"],"issn-type":[{"value":"0022-5282","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}