{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:22:14Z","timestamp":1789881734995,"version":"4.0.1"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1097\/ta.0b013e3181978e7b","type":"journal-article","created":{"date-parts":[[2009,5,21]],"date-time":"2009-05-21T19:43:51Z","timestamp":1242935031000},"page":"942-950","source":"Crossref","is-referenced-by-count":90,"title":["Management of Prehospital Antiplatelet and Anticoagulant Therapy in Traumatic Head Injury: A Review"],"prefix":"10.1097","volume":"66","author":[{"given":"Wesley D.","family":"McMillian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick B.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-60-20210211","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/01.ta.0000196542.54344.05","article-title":"Traumatic brain injury in anticoagulated patients.","volume":"60","author":"Cohen","year":"2006","journal-title":"J Trauma"},{"key":"R2-60-20210211","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0735-6757(99)90050-5","article-title":"Outcomes of anticoagulated trauma patients.","volume":"17","author":"Ferrera","year":"1999","journal-title":"Am J Emerg Med"},{"key":"R3-60-20210211","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/01.ta.0000224220.89528.fc","article-title":"Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma.","volume":"61","author":"Franko","year":"2006","journal-title":"J Trauma"},{"key":"R4-60-20210211","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1136\/jnnp.52.7.829","article-title":"Anticoagulation-related intracranial extracerebral haemorrhage.","volume":"52","author":"Mattle","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R5-60-20210211","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1126\/science.280.5367.1268","article-title":"Aspirin-like molecules that covalently inactivate cyclooxygenase-2.","volume":"280","author":"Kalgutkar","year":"1998","journal-title":"Science"},{"key":"R6-60-20210211","first-page":"48","article-title":"Cyclooxygenase-2 inhibitors as anti-inflammatory agents.","volume":"8","author":"Chang","year":"1998","journal-title":"Korean J Med Chem"},{"key":"R7-60-20210211","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1146\/annurev.pharmtox.38.1.97","article-title":"Cyclooxygenases 1 and 2.","volume":"38","author":"Vane","year":"1998","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"R8-60-20210211","article-title":"AHFS Drug Information.","author":"McEvoy","year":"2005"},{"key":"R9-60-20210211","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1056\/NEJM199202063260605","article-title":"Mortality over a period of 10 years in patients with peripheral arterial disease.","volume":"326","author":"Criqui","year":"1992","journal-title":"N Engl J Med"},{"key":"R11-60-20210211","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1161\/01.ATV.12.4.430","article-title":"Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.","volume":"12","author":"Mills","year":"1992","journal-title":"Arterioscler Thromb"},{"key":"R12-60-20210211","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1532-5415.1995.tb07329.x","article-title":"Predictors of hospital mortality in older patients with subdural hematoma.","volume":"43","author":"Rozzelle","year":"1995","journal-title":"J Am Geriatr Soc"},{"key":"R13-60-20210211","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/00005373-200210000-00008","article-title":"Intracranial complications of preinjury anticoagulation in trauma patients with head injury.","volume":"53","author":"Mina","year":"2002","journal-title":"J Trauma"},{"key":"R14-60-20210211","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3171\/jns.2003.99.4.0661","article-title":"Low-dose aspirin prophylaxis and risk of intracranial hemorrhage in patients older than 60 years of age with mild or moderate head injury: a prospective study.","volume":"99","author":"Spektor","year":"2003","journal-title":"J Neurosurg"},{"key":"R15-60-20210211","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1097\/01.TA.0000151671.35280.8B","article-title":"Effects of antiplatelet agents on outcomes for elderly patients with traumatic intracranial hemorrhage.","volume":"58","author":"Ohm","year":"2005","journal-title":"J Trauma"},{"key":"R16-60-20210211","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.amjsurg.2006.08.037","article-title":"The effects of preinjury clopidogrel use on older trauma patients with head injuries.","volume":"192","author":"Jones","year":"2006","journal-title":"Am J Surg"},{"key":"R17-60-20210211","doi-asserted-by":"crossref","first-page":"S329","DOI":"10.1053\/hj.1998.v135.90304","article-title":"Pharmacology of the low-molecular-weight heparins.","volume":"135","author":"Turpie","year":"1998","journal-title":"Am Heart J"},{"key":"R18-60-20210211","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1177\/106002809502900912","article-title":"Thrombosis and the pharmacology of antithrombotic agents.","volume":"29","author":"Haines","year":"1995","journal-title":"Ann Pharmacother"},{"key":"R19-60-20210211","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJM200103013440901","article-title":"A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement.","volume":"344","author":"Turpie","year":"2001","journal-title":"N Engl J Med"},{"key":"R20-60-20210211","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1177\/000313480106701114","article-title":"Traumatic head injury in the anticoagulated elderly patient: a lethal combination.","volume":"67","author":"Karni","year":"2001","journal-title":"Am Surg"},{"key":"R21-60-20210211","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1097\/01.TA.0000066183.02177.AF","article-title":"Preinjury warfarin use among elderly patients with closed head injuries in a trauma center.","volume":"56","author":"Lavoie","year":"2004","journal-title":"J Trauma"},{"key":"R22-60-20210211","first-page":"525","article-title":"Degree of anticoagulation, but not warfarin use itself, predicts adverse outcomes after traumatic brain injury in elderly trauma patients.","volume":"63","author":"Pieracci","year":"2007","journal-title":"J Trauma"},{"key":"R23-60-20210211","first-page":"1147","article-title":"Preinjury warfarin does not impact outcome in trauma patients.","volume":"51","author":"Wojcik","year":"2001","journal-title":"J Trauma"},{"key":"R24-60-20210211","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1111\/j.1538-7836.2006.02088.x","article-title":"Recombinant factor VIIa reverses the inhibitory effect of aspirin or aspirin plus clopidogrel on in vitro thrombin generation.","volume":"4","author":"Altman","year":"2006","journal-title":"J Thromb Haemost"},{"key":"R25-60-20210211","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1046\/j.1538-7836.2003.00190.x","article-title":"Cellular mechanisms of the hemostatic effects of desmopressin (DDAVP).","volume":"1","author":"Kaufmann","year":"2003","journal-title":"J Thromb Haemost"},{"key":"R26-60-20210211","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1055\/s-0038-1657715","article-title":"The effect of active site-inhibited factor VIIa on tissue factor-initiated coagulation using platelets before and after aspirin administration.","volume":"78","author":"Kjalke","year":"1997","journal-title":"Thromb Haemost"},{"key":"R27-60-20210211","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1227\/01.NEU.0000179915.74429.b2","article-title":"Counteracting the effects of anticoagulants and antiplatelet agents during neurosurgical emergencies.","volume":"57","author":"Powner","year":"2005","journal-title":"Neurosurgery"},{"key":"R28-60-20210211","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1538-7836.2006.02245.x","article-title":"Normalization of platelet reactivity in clopidogrel-treated subjects.","volume":"5","author":"Vilahur","year":"2007","journal-title":"J Thromb Haemost"},{"key":"R29-60-20210211","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1053\/j.jvca.2007.05.009","article-title":"Platelet mapping and desmopressin reversal of platelet inhibition during emergency carotid endarterectomy.","volume":"21","author":"Ranucci","year":"2007","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"3 suppl","key":"R30-60-20210211","doi-asserted-by":"crossref","first-page":"204S","DOI":"10.1378\/chest.126.3_suppl.204S","article-title":"The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.","volume":"126","author":"Ansell","year":"2004","journal-title":"Chest"},{"issue":"6 Suppl","key":"R31-60-20210211","first-page":"S41","article-title":"Cumulative risks of early fresh frozen plasma, cryoprecipitate and platelet transfusion in Europe.","volume":"60","author":"Norda","year":"2006","journal-title":"J Trauma"},{"key":"R32-60-20210211","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/01.ta.0000223944.25922.91","article-title":"Treatment of trauma patients with intracranial hemorrhage on preinjury warfarin.","volume":"61","author":"Ivascu","year":"2006","journal-title":"J Trauma"},{"key":"R33-60-20210211","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1097\/01.ta.0000189067.16368.83","article-title":"Rapid warfarin reversal in anticoagulated patients with traumatic intracranial hemorrhage reduces hemorrhage progression and mortality.","volume":"59","author":"Ivascu","year":"2005","journal-title":"J Trauma"},{"key":"R35-60-20210211","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1227\/01.neu.0000316898.78371.74","article-title":"Recombinant factor VIIA in traumatic intracerebral hemorrhage: results of a dose-escalation clinical trial.","volume":"62","author":"Narayan","year":"2008","journal-title":"Neurosurgery"},{"key":"R36-60-20210211","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1056\/NEJMoa042991","article-title":"Recombinant activated factor VII for acute intracerebral hemorrhage.","volume":"352","author":"Mayer","year":"2005","journal-title":"N Engl J Med"},{"key":"R37-60-20210211","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1056\/NEJMoa0707534","article-title":"Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage.","volume":"358","author":"Mayer","year":"2008","journal-title":"N Engl J Med"},{"key":"R38-60-20210211","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1097\/01.TA.0000140646.66852.AB","article-title":"Factor VIIa for correction of traumatic coagulopathy.","volume":"57","author":"Dutton","year":"2004","journal-title":"J Trauma"},{"key":"R39-60-20210211","first-page":"644","article-title":"Consensus recommendations for the off-label use of recombinant human factor VIIa (Novoseven) therapy.","volume":"30","author":"Shander","year":"2005","journal-title":"Pharm Ther"},{"key":"R40-60-20210211","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1592\/phco.26.8.1091","article-title":"Reversal of elevated international normalized ratios and bleeding with low-dose recombinant activated factor VII in patients receiving warfarin.","volume":"26","author":"Dager","year":"2006","journal-title":"Pharmacotherapy"}],"container-title":["Journal of Trauma: Injury, Infection &amp; Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/TA.0b013e3181978e7b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T18:54:43Z","timestamp":1710356083000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00005373-200903000-00060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/ta.0b013e3181978e7b","relation":{},"ISSN":["0022-5282"],"issn-type":[{"value":"0022-5282","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}