{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:19:49Z","timestamp":1786119589518,"version":"build-2736575974"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1097\/ta.0b013e31820d0dcc","type":"journal-article","created":{"date-parts":[[2011,3,10]],"date-time":"2011-03-10T03:17:53Z","timestamp":1299727073000},"page":"636-645","source":"Crossref","is-referenced-by-count":34,"title":["Hemostatic and Pharmacologic Resuscitation: Results of a Long-Term Survival Study in a Swine PolyTrauma Model"],"prefix":"10.1097","volume":"70","author":[{"given":"Hasan B.","family":"Alam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristopher B.","family":"Hamwi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Duggan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Fikry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene Y.","family":"Fukudome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Bramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyuseok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Velmahos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-17-20210211","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00005373-199502000-00006","article-title":"Epidemiology of trauma deaths: a reassessment.","volume":"38","author":"Sauaia","year":"1995","journal-title":"J Trauma"},{"key":"R2-17-20210211","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S1072-7515(98)00082-9","article-title":"Lethal injuries and time to death in a level I trauma center.","volume":"186","author":"Acosta","year":"1998","journal-title":"J Am Coll Surg"},{"key":"R3-17-20210211","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0196-0644(05)80195-7","article-title":"Effect of blood pressure on hemorrhage volume and survival in a near-fatal hemorrhage model incorporating a vascular injury.","volume":"22","author":"Stern","year":"1993","journal-title":"Ann Emerg Med"},{"key":"R4-17-20210211","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0039-6060(96)80262-5","article-title":"Effects of isotonic saline solution resuscitation on blood coagulation in uncontrolled hemorrhage.","volume":"119","author":"Selby","year":"1996","journal-title":"Surgery"},{"issue":"Suppl","key":"R5-17-20210211","first-page":"S100","article-title":"Blood pressure at which rebleeding occurs after resuscitation in swine with aortic injury.","volume":"54","author":"Sondeen","year":"2003","journal-title":"J Trauma"},{"key":"R6-17-20210211","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1097\/00005373-199309000-00008","article-title":"\u201cDamage Control\u201d: an approach for improved survival in exsanguinating penetrating abdominal trauma.","volume":"35","author":"Rotondo","year":"1993","journal-title":"J Trauma"},{"key":"R7-17-20210211","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/01.TA.0000062968.69867.6F","article-title":"Fluid resuscitation strategies: a systematic review of animal trials.","volume":"55","author":"Mapstone","year":"2003","journal-title":"J Trauma"},{"key":"R8-17-20210211","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/00005373-200010000-00003","article-title":"Advanced or basic life support for trauma: meta-analysis and critical review of the literature.","volume":"49","author":"Liberman","year":"2000","journal-title":"J Trauma"},{"key":"R9-17-20210211","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1056\/NEJM199410273311701","article-title":"Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries.","volume":"331","author":"Bickel","year":"1994","journal-title":"N Engl J Med"},{"key":"R10-17-20210211","first-page":"307","article-title":"Damage control resuscitation: directly addressing the early coagulopathy of trauma.","volume":"62","author":"Holcomb","year":"2007","journal-title":"J Trauma"},{"key":"R11-17-20210211","first-page":"856","article-title":"Testing of blood products in a polytrauma model: results of a multi-institutional randomized pre- clinical trial.","volume":"67","author":"Alam","year":"2009","journal-title":"J Trauma"},{"key":"R12-17-20210211","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/01.ta.0000250497.08101.8b","article-title":"Fresh frozen plasma should be given earlier to patients receiving massive transfusion.","volume":"62","author":"Gonzales","year":"2007","journal-title":"J Trauma"},{"key":"R13-17-20210211","first-page":"805","article-title":"The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital.","volume":"63","author":"Borgman","year":"2007","journal-title":"J Trauma"},{"key":"R14-17-20210211","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/01.ta.0000222671.84335.64","article-title":"Fresh whole blood transfusion: a controversial military practice.","volume":"61","author":"Kauvar","year":"2006","journal-title":"J Trauma"},{"key":"R15-17-20210211","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/MOH.0b013e3282ef477f","article-title":"Scientific aspects of supplying blood to distant military theaters.","volume":"14","author":"Johnson","year":"2007","journal-title":"Curr Opin Hematol"},{"key":"R16-17-20210211","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.surg.2005.08.022","article-title":"Cardiac histones are substrates of histone deacetylase activity in hemorrhagic shock and resuscitation.","volume":"139","author":"Lin","year":"2006","journal-title":"Surgery"},{"key":"R17-17-20210211","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.resuscitation.2007.07.030","article-title":"Impact of resuscitation strategies on the acetylation status of cardiac histones in a swine model of hemorrhage.","volume":"76","author":"Alam","year":"2008","journal-title":"Resuscitation"},{"key":"R18-17-20210211","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.surg.2008.03.037","article-title":"Cell protective mechanism of valproic acid in lethal hemorrhagic shock.","volume":"144","author":"Li","year":"2008","journal-title":"Surgery"},{"key":"R19-17-20210211","first-page":"554","article-title":"Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock.","volume":"65","author":"Gonzales","year":"2008","journal-title":"J Trauma"},{"key":"R20-17-20210211","first-page":"629","article-title":"Surviving blood loss without fluid resuscitation.","volume":"64","author":"Shults","year":"2008","journal-title":"J Trauma"},{"key":"R21-17-20210211","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.surg.2009.04.007","article-title":"Surviving blood loss without blood transfusion in a swine poly-trauma model.","volume":"146","author":"Alam","year":"2009","journal-title":"Surgery"},{"key":"R22-17-20210211","first-page":"863","article-title":"Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition.","volume":"64","author":"Li","year":"2008","journal-title":"J Trauma"},{"key":"R23-17-20210211","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jss.2010.04.013","article-title":"Pharmacologic resuscitation promotes survival and attenuates hemorrhage-induced activation of extracellular signal-regulated kinase 1\/2.","volume":"163","author":"Fukudome","year":"2010","journal-title":"J Surg Res"},{"key":"R24-17-20210211","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jss.2009.04.012","article-title":"Pharmacologic resuscitation: cell protective mechanisms of histone deacetylase inhibition in lethal hemorrhagic shock.","volume":"156","author":"Butt","year":"2009","journal-title":"J Surg Res"},{"key":"R25-17-20210211","first-page":"325","article-title":"Protective effect of suberoylanilide hydroxamic acid against LPS-induced septic shock in rodents.","volume":"146","author":"Li","year":"2009","journal-title":"Shock"},{"key":"R26-17-20210211","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.surg.2008.03.034","article-title":"Acetylation: a novel method for modulation of the immune response following trauma\/hemorrhage and inflammatory second hit in animals and humans.","volume":"144","author":"Sailhamer","year":"2008","journal-title":"Surgery"},{"key":"R27-17-20210211","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.surg.2010.05.003","article-title":"Surviving lethal septic shock without fluid resuscitation in a rodent model.","volume":"48","author":"Li","year":"2010","journal-title":"Surgery"},{"key":"R28-17-20210211","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.cyto.2009.11.013","article-title":"Hypoxic \u201csecond hit\u201d in leukocytes from trauma patients: modulation of the immune response by histone deacetylase inhibition.","volume":"49","author":"Sailhamer","year":"2010","journal-title":"Cytokine"},{"key":"R29-17-20210211","first-page":"975","article-title":"Development and testing of freeze dried plasma for the treatment of trauma associated coagulopathy.","volume":"65","author":"Shuja","year":"2008","journal-title":"J Trauma"},{"key":"R30-17-20210211","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1001\/archsurg.2009.154","article-title":"Lyophilized plasma for resuscitation in a swine model of severe injuries.","volume":"144","author":"Spoerke","year":"2009","journal-title":"Arch Surg"},{"key":"R31-17-20210211","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1073\/pnas.0611430104","article-title":"Drying a tuberculosis vaccine without freezing.","volume":"104","author":"Wong","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R32-17-20210211","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1097\/TA.0b013e31820e83be","article-title":"Development and testing of low volume hypertonic, hyperoncotic spray dried plasma for the treatment of trauma-associated coagulopathy.","volume":"70","author":"Shuja","year":"2011","journal-title":"J Trauma"},{"key":"R33-17-20210211","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.surg.2007.01.014","article-title":"Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver.","volume":"141","author":"Lin","year":"2007","journal-title":"Surgery"},{"key":"R34-17-20210211","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/SHK.0b013e3181c30f0c","article-title":"Fluid resuscitation: past, present and the future.","volume":"33","author":"Santry","year":"2010","journal-title":"Shock"},{"key":"R35-17-20210211","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.suc.2006.09.015","article-title":"New developments in fluid resuscitation.","volume":"87","author":"Alam","year":"2007","journal-title":"Surg Clin North Am"}],"container-title":["Journal of Trauma: Injury, Infection & Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/TA.0b013e31820d0dcc","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:55:52Z","timestamp":1786042552000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005373-201103000-00017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/ta.0b013e31820d0dcc","relation":{},"ISSN":["0022-5282"],"issn-type":[{"value":"0022-5282","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}