{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T23:58:32Z","timestamp":1789084712842,"version":"build-2803163510"},"reference-count":58,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background.<\/jats:title>\n                    <jats:p>The number of patients awaiting liver transplantation (LT) in Spain has halved from 2015 to 2019 due to the reduction of candidates with hepatitis C and the successful implementation of nonheart beating donation programs across the country. The Spanish Society for Liver Transplantation has committed to take advantage of this situation by developing consensus around potential areas to expand the current indications for LT. The consensus group was composed of 6 coordinators and 23 expert delegates, each one representing an LT institution in Spain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>A modified Delphi approach was used to identify areas to expand indications for LT and to build consensus around paramount aspects, such as inclusion criteria and waitlist prioritization within each area. The scientific evidence and strength of recommendations were assessed by the \u201cGrading of Recommendations Assessment, Development, and Evaluation\u201d system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>The consensus process resulted in the identification of 7 potential areas to expand criteria in LT: recipient\u2019s age, hepatocellular carcinoma, alcoholic hepatitis, acute-on-chronic liver failure, hilar and intrahepatic cholangiocarcinoma, and unresectable liver metastases of colorectal cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>We present the main recommendations issued for each topic, together with their core supporting evidence. These recommendations may allow for expanding criteria for LT homogenously in Spain and may provide a guidance to other countries\/institutions facing a similar scenario.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/tp.0000000000003281","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T18:48:53Z","timestamp":1588099733000},"page":"602-607","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":46,"title":["Expanding Indications of Liver Transplantation in Spain: Consensus Statement and Recommendations by the Spanish Society of Liver Transplantation"],"prefix":"10.1097","volume":"105","author":[{"given":"Manuel","family":"Rodr\u00edguez-Per\u00e1lvarez","sequence":"first","affiliation":[{"name":"Department of Hepatology and Liver Transplantation, Hospital Universitario Reina Sof\u00eda, IMIBIC, CIBERehd, C\u00f3rdoba, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel \u00c1ngel","family":"G\u00f3mez-Bravo","sequence":"additional","affiliation":[{"name":"Department of Abdominal Surgery and Transplantation, Hospital Universitario Virgen del Roc\u00edo, Sevilla, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"S\u00e1nchez-Antol\u00edn","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Liver Transplantation, Hospital Universitario Rio Hortega, Valladolid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"De la Rosa","sequence":"additional","affiliation":[{"name":"Organizaci\u00f3n Nacional de Trasplantes, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itxarone","family":"Bilbao","sequence":"additional","affiliation":[{"name":"Department of Liver Transplantation, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Colmenero","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Liver Transplantation, Hospital Cl\u00ednic de Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,2,22]]},"reference":[{"key":"R1-20250604","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1111\/ajt.14296","article-title":"About the opt-out system, live transplantation, and information to the public on organ donation in Spain \u2026 Y ol\u00e9!","volume":"17","author":"Matesanz","year":"2017","journal-title":"Am J Transplant"},{"key":"R2-20250604","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1111\/ajt.15253","article-title":"Summary of Spanish recommendations on intensive care to facilitate organ 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