{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:23:47Z","timestamp":1793654627294,"version":"4.5.1"},"reference-count":56,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Uterus transplantation (UTx) became a clinical reality with the birth of the first baby in 2014. Following increased success, the procedure has now transitioned to clinical practice in many institutions throughout the world. With a rising number of donors, recipients, and babies born from this procedure, and with more institutions offering UTx, ethical challenges have evolved while novel aspects gained prominence. Here, the Ethics Committees of the International Uterus Transplantation Society, a section of The Transplantation Society, summarize current and future ethical challenges in UTx and provide recommendations for addressing these challenges. Ethical considerations covered here span (i) donor and recipient selection, (ii) living versus deceased donation, (iii) use of assisted reproductive technologies, (iv) informed consent, (v) clinical provision of UTx, and (vi) research protocols for further studies of UTx. For each topic considered, ethical analysis and recommendations are offered to ensure the practice of UTx remains within an acceptable foundational ethical framework that balances respect for autonomy, beneficence, and justice.<\/jats:p>","DOI":"10.1097\/tp.0000000000005507","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T04:00:59Z","timestamp":1756180859000},"page":"1836-1844","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Evolving Ethical Challenges After a Decade of Uterus Transplantation: Recommendations From the International Society of Uterus Transplantation Ethics Committee"],"prefix":"10.1097","volume":"109","author":[{"given":"Anji E.","family":"Wall","sequence":"first","affiliation":[{"name":"Department of Transplant Surgery, Baylor University Medical Center, Dallas, TX."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Br\u00e4nnstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mianna","family":"Lotz","sequence":"additional","affiliation":[{"name":"Department of Philosophy, School of Humanities and Ethics and Agency Research Centre, Macquarie University, Sydney, NSW, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Racowsky","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Foch, Suresnes, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Stock","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery, University of California San Francisco, San Francisco, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stina","family":"J\u00e4rvholm","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Sustek","sequence":"additional","affiliation":[{"name":"Faculty of Law, Charles University, Prague, Czech Republic."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Brucker","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s Health, University Women\u2019s Hospital, Tubingen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan G.","family":"Tullius","sequence":"additional","affiliation":[{"name":"Brigham Hospital and Women\u2019s Hospital, Division of Transplant Surgery, Harvard University, Boston, MA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of The International Society of Uterus Transplantation Ethics Committee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"endorsed by The Transplantation Society Ethics Committee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,8,26]]},"reference":[{"key":"R1-20251126","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S0140-6736(14)61728-1","article-title":"Livebirth after uterus transplantation.","volume":"385","author":"Brannstrom","year":"2015","journal-title":"Lancet"},{"key":"R2-20251126","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/TP.0000000000004286","article-title":"Registry of the International Society of Uterus Transplantation: First 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