{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T17:52:48Z","timestamp":1791741168871,"version":"4.3.4"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,10,27]]},"DOI":"10.1097\/tp.0b013e3181b9d710","type":"journal-article","created":{"date-parts":[[2009,10,22]],"date-time":"2009-10-22T03:28:00Z","timestamp":1256182080000},"page":"1019-1024","source":"Crossref","is-referenced-by-count":269,"title":["High Risk of Graft Failure in Patients With Anti-HLA Antibodies Undergoing Haploidentical Stem-Cell Transplantation"],"prefix":"10.1097","volume":"88","author":[{"given":"Stefan O.","family":"Ciurea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"de Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Cano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Korbling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Giralt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Shpall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter F.","family":"Thall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Champlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Fernandez-Vina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210211","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1056\/NEJM199303043280901","article-title":"Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program.","volume":"328","author":"Kernan","year":"1993","journal-title":"N Engl J Med"},{"key":"R2-12-20210211","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1056\/NEJM199810223391702","article-title":"Treatment of high-risk acute leukemia with T-cell depleted stem cells from related donors with one fully mismatched HLA haplotype.","volume":"339","author":"Aversa","year":"1998","journal-title":"N Eng J Med"},{"key":"R3-12-20210211","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1056\/NEJMra052638","article-title":"Hematopoietic stem-cell transplantation.","volume":"354","author":"Copelan","year":"2006","journal-title":"N Engl J Med"},{"key":"R4-12-20210211","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/S0140-6736(84)91323-0","article-title":"Long-term remissions in acute myelogenous leukaemia.","volume":"1","author":"Powles","year":"1984","journal-title":"Lancet"},{"key":"R5-12-20210211","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1056\/NEJM198509263131301","article-title":"Marrow transplantation from related donors other then HLA-identical siblings.","volume":"313","author":"Beatty","year":"1995","journal-title":"N Engl J Med"},{"key":"R6-12-20210211","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1038\/nm1295-1268","article-title":"Megadose of T-cell depleted bone marrow overcomes MHC barriers in sublethally irradiated mice.","volume":"1","author":"Bachar-Lustig","year":"1995","journal-title":"Nat Med"},{"key":"R7-12-20210211","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.bcmd.2004.08.017","article-title":"Long-term outcome after haploidentical stem cell transplantation in children.","volume":"33","author":"Lang","year":"2004","journal-title":"Blood Cells Mol Dis"},{"key":"R8-12-20210211","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.1182\/blood-2008-02-140095","article-title":"A survey of fully-haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: A risk factor analysis of outcomes for patients transplanted in remission.","volume":"112","author":"Ciceri","year":"2008","journal-title":"Blood"},{"key":"R9-12-20210211","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.bbmt.2007.08.003","article-title":"Allogeneic hematopoietic stem cell transplant using mismatched\/haploidentical donors.","volume":"13","author":"Koh","year":"2007","journal-title":"Biol Blood Marrow Transplant"},{"key":"R10-12-20210211","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1056\/NEJM196904032801401","article-title":"Significance of positive crossmatch in kidney transplantation.","volume":"280","author":"Patel","year":"1969","journal-title":"N Engl J Med"},{"key":"R11-12-20210211","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1056\/NEJM199409223311203","article-title":"The impact of HLA mismatches on the survival of first cadaveric kidney transplants.","volume":"331","author":"Held","year":"1994","journal-title":"N Engl J Med"},{"key":"R12-12-20210211","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1097\/00007890-199103000-00033","article-title":"The role of anti-HLA antibodies in heart transplantation.","volume":"51","author":"Suciu-Foca","year":"1991","journal-title":"Transplantation"},{"key":"R13-12-20210211","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1600-6143.2004.00360.x","article-title":"Predicting kidney graft failure by HLA antibodies a prospective trial.","volume":"4","author":"Terasaki","year":"2004","journal-title":"Am J Transplant"},{"key":"R14-12-20210211","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1111\/j.1600-6143.2006.01711.x","article-title":"Extremely high association between appearance of HLA antibodies and failure of kidney grafts in a five-year longitudinal study.","volume":"7","author":"Mao","year":"2007","journal-title":"Am J Transplant"},{"key":"R15-12-20210211","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/00007890-200002150-00001","article-title":"Anti-HLA antibodies after solid organ transplantation.","volume":"69","author":"McKenna","year":"2000","journal-title":"Transplantation"},{"key":"R16-12-20210211","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1111\/j.1600-6143.2006.01521.x","article-title":"Transplanting the highly sensitized patient: The Emory algorithm.","volume":"6","author":"Bray","year":"2006","journal-title":"Am J Transplant"},{"key":"R17-12-20210211","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1056\/NEJM198901263200401","article-title":"Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia and lymphoma.","volume":"320","author":"Anasetti","year":"1989","journal-title":"N Engl J Med"},{"key":"R18-12-20210211","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1097\/00007890-200204270-00016","article-title":"Positive serum crossmatch as predictor for graft failure in HLA-mismatched allogeneic blood stem cell transplantation.","volume":"73","author":"Ottinger","year":"2002","journal-title":"Transplantation"},{"key":"R19-12-20210211","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.humimm.2008.06.013","article-title":"Detecting and monitoring human leukocyte antigen-specific antibodies.","volume":"69","author":"Zachary","year":"2008","journal-title":"Hum Immunol"},{"key":"R20-12-20210211","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1182\/blood-2006-05-022772","article-title":"Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients.","volume":"109","author":"Taylor","year":"2007","journal-title":"Blood"},{"key":"R21-12-20210211","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00007890-200301150-00008","article-title":"Single human leukocyte antigen flow cytometry beads for accurate identification of HLA antibody specificities.","volume":"75","author":"Pei","year":"2003","journal-title":"Transplantation"},{"key":"R22-12-20210211","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/cyto.990110203","article-title":"High gradient magnetic cell separation with MACS.","volume":"11","author":"Miltenyi","year":"1990","journal-title":"Cytometry"},{"key":"R23-12-20210211","doi-asserted-by":"crossref","first-page":"5081a","DOI":"10.1182\/blood.V110.11.5081.5081","article-title":"Sustained engraftment using fludarabine, melphalan and thiotepa conditioning for haploidentical stem cell transplantation.","volume":"351B","author":"Ciurea","year":"2007","journal-title":"Blood"},{"key":"R24-12-20210211","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1111\/j.1600-6143.2007.01991.x","article-title":"C4d fixing, luminex binding antibodies a new tool for prediction of graft failure after heart transplantation.","volume":"7","author":"Smith","year":"2007","journal-title":"Am J Transplant"},{"key":"R25-12-20210211","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2307\/2340521","article-title":"On the interpretation of \u03c72 from contingency tables, and the calculation of P.","volume":"85","author":"Fisher","year":"1922","journal-title":"J R Stat Soc"},{"key":"R26-12-20210211","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1080\/01621459.1987.10478547","article-title":"Computing distributions for exact logistic regression.","volume":"82","author":"Karim","year":"1987","journal-title":"J Am Stat Assoc"},{"key":"R27-12-20210211","article-title":"Introduction to the theory of nonparametric statistics.","author":"Randles","year":"1979"},{"key":"R28-12-20210211","doi-asserted-by":"crossref","first-page":"3611","DOI":"10.1182\/blood-2006-04-017467","article-title":"Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients.","volume":"108","author":"Xu","year":"2006","journal-title":"Blood"},{"key":"R29-12-20210211","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/00007890-200009270-00006","article-title":"Plasmapheresis and intravenous immune globulin provides effective rescue therapy for refractory humoral rejection and allows kidneys to be successfully transplanted into cross-match-positive recipients.","volume":"70","author":"Montgomery","year":"2000","journal-title":"Transplantation"},{"key":"R30-12-20210211","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1600-6143.2003.00646.x","article-title":"Rituximab (Rituxan) inhibits the in vivo primary and secondary antibody response to a neoantigen, bacteriophage phiX174.","volume":"5","author":"Bearden","year":"2005","journal-title":"Am J Transplant"},{"key":"R31-12-20210211","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.humimm.2006.06.002","article-title":"Association of kidney transplant failure and antibodies against MICA.","volume":"67","author":"Mizutani","year":"2006","journal-title":"Hum Immunol"}],"container-title":["Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00007890-200910270-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:04:56Z","timestamp":1786039496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00007890-200910270-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,27]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/tp.0b013e3181b9d710","relation":{},"ISSN":["0041-1337"],"issn-type":[{"value":"0041-1337","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10,27]]}}}