{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:42:33Z","timestamp":1791258153399,"version":"4.1.0"},"reference-count":54,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1,27]]},"DOI":"10.1097\/tp.0b013e3182a53f59","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T13:48:38Z","timestamp":1378907318000},"page":"127-132","source":"Crossref","is-referenced-by-count":38,"title":["Helminths and Immunological Tolerance"],"prefix":"10.1097","volume":"97","author":[{"given":"Chris J.C.","family":"Johnston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry J.","family":"McSorley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Anderton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Wigmore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick M.","family":"Maizels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210129","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1056\/NEJMra033540","article-title":"Immunosuppressive drugs for kidney transplantation.","volume":"351","author":"Halloran","year":"2004","journal-title":"N Engl J Med"},{"key":"R2-4-20210129","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/nm.2507","article-title":"Ischemia and reperfusionfrom mechanism to translation.","volume":"17","author":"Eltzschig","year":"2011","journal-title":"Nat Med"},{"key":"R3-4-20210129","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1432-2277.2011.01327.x","article-title":"Rationing life-saving resourceshow should allocation policies be assessed in solid organ transplantation.","volume":"25","author":"Neuberger","year":"2011","journal-title":"Transpl Int"},{"key":"R4-4-20210129","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1600-6143.2004.00332.x","article-title":"Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era.","volume":"4","author":"Meier-Kriesche","year":"2004","journal-title":"Am J Transplant"},{"key":"R5-4-20210129","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/j.1600-6143.2010.03283.x","article-title":"Long-term renal allograft survival in the United States: a critical reappraisal.","volume":"11","author":"Lamb","year":"2010","journal-title":"Am J Transplant"},{"key":"R6-4-20210129","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1111\/j.1600-6143.2011.03539.x","article-title":"Solid organ allograft survival improvement in the United States: the long-term does not mirror the dramatic short-term success.","volume":"11","author":"Lodhi","year":"2011","journal-title":"Am J Transplant"},{"key":"R7-4-20210129","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1056\/NEJMra064928","article-title":"Infection in solid-organ transplant recipients.","volume":"357","author":"Fishman","year":"2007","journal-title":"N Engl J Med"},{"key":"R8-4-20210129","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1046\/j.1600-6143.2003.00325.x","article-title":"Lymphomas after solid organ transplantation: a collaborative transplant study report.","volume":"4","author":"Opelz","year":"2004","journal-title":"Am J Transplant"},{"key":"R9-4-20210129","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1600-065X.2011.01019.x","article-title":"Mechanisms of tolerance.","volume":"241","author":"Bluestone","year":"2011","journal-title":"Immunol Rev"},{"key":"R10-4-20210129","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/172603a0","article-title":"Actively acquired tolerance of foreign cells.","volume":"172","author":"Billingham","year":"1953","journal-title":"Nature"},{"key":"R11-4-20210129","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nri3227","article-title":"Regulatory immune cells in transplantation.","volume":"12","author":"Wood","year":"2012","journal-title":"Nat Rev Immunol"},{"key":"R12-4-20210129","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1056\/NEJMoa071074","article-title":"HLA-mismatched renal transplantation without maintenance immunosuppression.","volume":"358","author":"Kawai","year":"2008","journal-title":"N Engl J Med"},{"key":"R13-4-20210129","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1111\/j.1600-6143.2012.03992.x","article-title":"Tolerance and withdrawal of immunosuppressive drugs in patients given kidney and hematopoietic cell transplants.","volume":"12","author":"Scandling","year":"2012","journal-title":"Am J Transplant"},{"key":"R14-4-20210129","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.smim.2003.12.007","article-title":"Regulatory T cells and organ transplantation.","volume":"16","author":"Waldmann","year":"2004","journal-title":"Semin Immunol"},{"key":"R15-4-20210129","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.clim.2009.06.001","article-title":"First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4CD25CD127- T regulatory cells.","volume":"133","author":"Trzonkowski","year":"2009","journal-title":"Clin Immunol"},{"key":"R16-4-20210129","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.coi.2011.06.006","article-title":"Regulatory T cells in stem cell transplantation: strategies and first clinical experiences.","volume":"23","author":"Edinger","year":"2011","journal-title":"Curr Opin Immunol"},{"key":"R17-4-20210129","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1126\/science.332.6033.1020","article-title":"Immunology. Regulatory T cells get their chance to shine.","volume":"332","author":"Leslie","year":"2011","journal-title":"Science"},{"key":"R18-4-20210129","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.smim.2011.04.001","article-title":"Moving to tolerance: clinical application of T regulatory cells.","volume":"23","author":"McMurchy","year":"2011","journal-title":"Semin Immunol"},{"key":"R19-4-20210129","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.4049\/jimmunol.174.6.3290","article-title":"The generation of CD25CD4 regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen.","volume":"174","author":"Bushell","year":"2005","journal-title":"J Immunol"},{"key":"R20-4-20210129","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/gut.53.1.7","article-title":"Helminths and harmony.","volume":"53","author":"Weinstock","year":"2004","journal-title":"Gut"},{"key":"R21-4-20210129","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/nri1183","article-title":"Immune regulation by helminth parasites: cellular and molecular mechanisms.","volume":"3","author":"Maizels","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"R22-4-20210129","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1128\/CMR.05040-11","article-title":"Helminth infections and host immune regulation.","volume":"25","author":"Mcsorley","year":"2012","journal-title":"Clin Microbiol Rev"},{"key":"R23-4-20210129","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jneuroim.2011.01.002","article-title":"The impact of parasite infections on the course of multiple sclerosis.","volume":"233","author":"Correale","year":"2011","journal-title":"J Neuroimmunol"},{"key":"R24-4-20210129","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1136\/gut.2004.041749","article-title":"Trichuris suis therapy in Crohns disease.","volume":"54","author":"Summers","year":"2005","journal-title":"Gut"},{"key":"R25-4-20210129","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ijpara.2012.10.016","article-title":"Translatability of helminth therapy in inflammatory bowel diseases.","volume":"43","author":"Weinstock","year":"2012","journal-title":"Int J Parasitol"},{"key":"R26-4-20210129","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1016\/j.transproceed.2005.03.111","article-title":"Orthotopic liver transplantation for incurable alveolar echinococcosis: report of five cases from West China.","volume":"37","author":"Xia","year":"2005","journal-title":"Transplant Proc"},{"key":"R27-4-20210129","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1002\/lt.22299","article-title":"Should possible recurrence of disease contraindicate liver transplantation in patients with end-stage alveolar echinococcosis A 20-year follow-up study.","volume":"17","author":"Bresson-Hadni","year":"2011","journal-title":"Liver Transpl"},{"key":"R28-4-20210129","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/hep.510300426","article-title":"Primary disease recurrence after liver transplantation for alveolar echinococcosis: long-term evaluation in 15 patients.","volume":"30","author":"Bresson-Hadni","year":"1999","journal-title":"Hepatology"},{"key":"R29-4-20210129","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0022-3476(97)70364-0","article-title":"Alveolar echinococcosis of the liver in a six-year-old girl with acquired immunodeficiency syndrome.","volume":"130","author":"Sailer","year":"1997","journal-title":"J Pediatr"},{"key":"R30-4-20210129","first-page":"231","article-title":"Guidelines for treatment of cystic and alveolar echinococcosis in humans.","volume":"74","year":"1996","journal-title":"Bull World Health Organ"},{"key":"R31-4-20210129","first-page":"2818","article-title":"Suppression of acute rejective response following orthotopic liver transplantation in experimental rats infected with Echinococcus multilocularis.","volume":"124","author":"Li","year":"2011","journal-title":"Chin Med J"},{"key":"R32-4-20210129","first-page":"4412","article-title":"Immune responses on allograft heart transplantation in inbred rats infected with Echinococcosis multilocularis.","volume":"125","author":"Hepiretihan","year":"2012","journal-title":"Chin Med J"},{"key":"R33-4-20210129","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/00007890-199601270-00003","article-title":"Prolongation of rat kidney allograft survival by nematodes.","volume":"61","author":"Ledingham","year":"1996","journal-title":"Transplantation"},{"key":"R34-4-20210129","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1097\/00007890-200005150-00029","article-title":"Prolongation of allograft survival by Nippostrongylus brasiliensis is associated with decreased allospecific cytotoxic T lymphocyte activity and development of T cytotoxic cell type 2 cells.","volume":"69","author":"Liwski","year":"2000","journal-title":"Transplantation"},{"key":"R35-4-20210129","doi-asserted-by":"crossref","first-page":"6959","DOI":"10.4049\/jimmunol.169.12.6959","article-title":"Nippostrongylus brasiliensis can induce B7-independent antigen-specific development of IL-4-producing T cells from naive CD4 T cells in vivo.","volume":"169","author":"Liu","year":"2002","journal-title":"J Immunol"},{"key":"R36-4-20210129","first-page":"17","article-title":"Tolerance in heart transplantation: the Holy Grail, or an attainable goal Heart Fail C","volume":"3","author":"Pierson","year":"2007","journal-title":"lin"},{"key":"R37-4-20210129","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1002\/lt.22316","article-title":"Schistosoma mansoni infection in the liver graft: the impact on donor and recipient outcomes after transplantation.","volume":"17","author":"Vincenzi","year":"2011","journal-title":"Liver Transpl"},{"key":"R38-4-20210129","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1016\/j.transproceed.2003.10.065","article-title":"Orthotopic liver transplantation from a donor with a history of schistosomiasis.","volume":"35","author":"Kayler","year":"2003","journal-title":"Transplant Proc"},{"key":"R39-4-20210129","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1002\/lt.23436","article-title":"Intentional use of Schistosoma mansoni-infected grafts in living donor liver transplantation.","volume":"18","author":"Andraus","year":"2012","journal-title":"Liver Transpl"},{"key":"R40-4-20210129","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1093\/ndt\/16.11.2214","article-title":"Impact of schistosomiasis on patient and graft outcome after renal transplantation: 10 years follow-up.","volume":"16","author":"Mahmoud","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"R41-4-20210129","first-page":"425","article-title":"Prolonged skin allograft survival in chronic schistosomiasis.","volume":"91","author":"Aboul-Enein","year":"1982","journal-title":"Surgery"},{"key":"R42-4-20210129","first-page":"289","article-title":"Schistosoma mansoni: impairment of the cell-mediated immune response in mice.","volume":"28","author":"Araujo","year":"1977","journal-title":"Clin Exp Immunol"},{"key":"R43-4-20210129","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0140-6736(69)90078-6","article-title":"Mouse transplantation immunity depressed by Trichinella spiralis.","volume":"2","author":"Svet-Moldavsky","year":"1969","journal-title":"Lancet"},{"key":"R44-4-20210129","first-page":"1041","article-title":"Leucoagglutination and cytotoxicity of the serum of infected mice and of extracts of Trichinella spiralis larvae and the capacity of infected mouse sera to prolong skin allografts.","volume":"28","author":"Faubert","year":"1975","journal-title":"Immunology"},{"key":"R45-4-20210129","first-page":"176","article-title":"The effect of Trichinella spiralis on graft-versus-host reaction, transplantation immunity and antibody formation.","volume":"25","author":"Chimyshkyan","year":"1976","journal-title":"Biomedicine"},{"key":"R46-4-20210129","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0147-9571(95)00005-S","article-title":"Suppression of transplant immunity in experimental trichinellosis.","volume":"18","author":"Alkarmi","year":"1995","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"R47-4-20210129","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.0105-2896.2004.00191.x","article-title":"Helminth parasitesmasters of regulation.","volume":"201","author":"Maizels","year":"2004","journal-title":"Immunol Rev"},{"key":"R48-4-20210129","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.exppara.2011.08.011","article-title":"Immune modulation and modulators in Heligmosomoides polygyrus infection.","volume":"132","author":"Maizels","year":"2012","journal-title":"Exp Parasitol"},{"key":"R49-4-20210129","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1002\/eji.200838871","article-title":"Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice.","volume":"39","author":"Zaccone","year":"2009","journal-title":"Eur J Immunol"},{"key":"R50-4-20210129","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1084\/jem.20082824","article-title":"In vivo expansion of Treg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression.","volume":"206","author":"Webster","year":"2009","journal-title":"J Exp Med"},{"key":"R51-4-20210129","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1016\/j.transproceed.2012.09.032","article-title":"Impact of interleukin-2-expanded regulatory T cells in various allogeneic combinations on mouse skin graft survival.","volume":"44","author":"Vokaer","year":"2012","journal-title":"Transplant Proc"},{"key":"R52-4-20210129","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1111\/j.1600-6143.2006.01489.x","article-title":"TLR engagement prevents transplantation tolerance.","volume":"6","author":"Chen","year":"2006","journal-title":"Am J Transplant"},{"key":"R53-4-20210129","doi-asserted-by":"crossref","first-page":"e22346","DOI":"10.1371\/journal.pone.0022346","article-title":"Symptoms after ingestion of pig whipworm Trichuris suis eggs in a randomized placebo-controlled double-blind clinical trial.","volume":"6","author":"Bager","year":"2011","journal-title":"PLoS One"},{"key":"R54-4-20210129","first-page":"109","article-title":"The therapeutic helminth Trends P","volume":"25","author":"McKay","year":"2009","journal-title":"arasitol"}],"container-title":["Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/TP.0b013e3182a53f59","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T07:36:24Z","timestamp":1620977784000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00007890-201401270-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,27]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1097\/tp.0b013e3182a53f59","relation":{},"ISSN":["0041-1337"],"issn-type":[{"value":"0041-1337","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1,27]]}}}