{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T07:29:27Z","timestamp":1791098967968,"version":"4.1.0"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1097\/wad.0000000000000005","type":"journal-article","created":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T12:40:04Z","timestamp":1381754404000},"page":"36-43","source":"Crossref","is-referenced-by-count":135,"title":["Body Mass Index, Weight Change, and Clinical Progression in Mild Cognitive Impairment and Alzheimer Disease"],"prefix":"10.1097","volume":"28","author":[{"given":"Lilah M.","family":"Besser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn P.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Monsell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willa","family":"Brenowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana H.","family":"Meranus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Kukull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah R.","family":"Gustafson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20210128","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1001\/archneur.59.11.1764","article-title":".Survival following a diagnosis of Alzheimer disease.","volume":"59","author":"Brookmeyer","year":"2002","journal-title":"Arch Neurol"},{"key":"R2-6-20210128","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3233\/JAD-2011-110443","article-title":".Dementia-associated mortality at thirteen years in the NEDICES Cohort Study.","volume":"26","author":"Villarejo","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"R3-6-20210128","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1001\/archneur.66.3.343","article-title":".Contribution of vascular risk factors to the progression in Alzheimer disease.","volume":"66","author":"Helzner","year":"2009","journal-title":"Arch Neurol"},{"key":"R4-6-20210128","doi-asserted-by":"crossref","first-page":"637S","DOI":"10.1093\/ajcn\/71.2.637s","article-title":".Weight loss in Alzheimer disease.","volume":"71","author":"Gillette-Guyonnet","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"R5-6-20210128","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1532-5415.1996.tb00912.x","article-title":"Weight Change in Alzheimers Disease.","volume":"44","author":"White","year":"1996","journal-title":"J Am Geriatr Soc"},{"key":"R6-6-20210128","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1001\/archneur.62.1.55","article-title":".A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study.","volume":"62","author":"Stewart","year":"2005","journal-title":"Arch Neurol"},{"key":"R7-6-20210128","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1001\/archneur.63.9.1312","article-title":"Accelerated weight loss may precede diagnosis in Alzheimer disease.","volume":"63","author":"Johnson","year":"2006","journal-title":"Arch Neurol"},{"key":"R8-6-20210128","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1212\/01.wnl.0000176061.33817.90","article-title":".Change in body mass index and risk of incident Alzheimer disease.","volume":"65","author":"Buchman","year":"2005","journal-title":"Neurology"},{"key":"R9-6-20210128","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1001\/archneurol.2008.582","article-title":".Midlife and late-life obesity and the risk of dementia: cardiovascular health study.","volume":"66","author":"Fitzpatrick","year":"2009","journal-title":"Arch Neurol"},{"key":"R10-6-20210128","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1212\/WNL.46.6.1585","article-title":".Low body weight in Alzheimers disease is associated with mesial temporal cortex atrophy.","volume":"46","author":"Grundman","year":"1996","journal-title":"Neurology"},{"key":"R11-6-20210128","first-page":"38","article-title":".IANA (International Academy on Nutrition and Aging) Expert Group: weight loss and Alzheimers disease.","volume":"11","author":"Gillette Guyonnet","year":"2007","journal-title":"J Nutr Health Aging"},{"key":"R12-6-20210128","doi-asserted-by":"crossref","first-page":"647","DOI":"10.3233\/JAD-2011-110713","article-title":".Weight loss and rapid cognitive decline in community-dwelling patients with Alzheimers disease.","volume":"28","author":"Soto","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"R13-6-20210128","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/WAD.0b013e3181a6bf3f","article-title":"Body mass index and cognitive decline in mild cognitive impairment.","volume":"24","author":"Cronk","year":"2010","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"R14-6-20210128","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.jalz.2011.01.005","article-title":".Suitability of the Clinical Dementia Rating-Sum of Boxes as a single primary endpoint for Alzheimers disease trials.","volume":"7","author":"Coley","year":"2011","journal-title":"Alzheimers Dement"},{"key":"R15-6-20210128","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/WAD.0b013e318142774e","article-title":".The National Alzheimers Coordinating Center (NACC) database: the Uniform Data Set.","volume":"21","author":"Beekly","year":"2007","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"R16-6-20210128","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/01.wad.0000213865.09806.92","article-title":".The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers.","volume":"20","author":"Morris","year":"2006","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"R18-6-20210128","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1212\/01.WNL.0000130531.90205.EF","article-title":".Memory impairment, but not cerebrovascular disease, predicts progression of MCI to dementia.","volume":"63","author":"DeCarli","year":"2004","journal-title":"Neurology"},{"key":"R19-6-20210128","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1212\/WNL.0b013e3181cb3e25","article-title":".Alzheimers Disease Neuroimaging Initiative (ADNI): clinical characterization.","volume":"74","author":"Petersen","year":"2010","journal-title":"Neurology"},{"key":"R20-6-20210128","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":".Clinical diagnosis of Alzheimers disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimers Disease.","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"R21-6-20210128","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1212\/WNL.43.11.2412-a","article-title":"The Clinical Dementia Rating (CDR): current version and scoring rules.","volume":"43","author":"Morris","year":"1993","journal-title":"Neurology"},{"key":"R22-6-20210128","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1001\/archneur.65.8.1091","article-title":".Staging dementia using Clinical Dementia Rating Scale Sum of Boxes scores: a Texas Alzheimers research consortium study.","volume":"65","author":"OBryant","year":"2008","journal-title":"Arch Neurol"},{"key":"R23-6-20210128","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/sj.ejcn.1601311","article-title":".Nutritional status of healthy elderly persons living in Dordogne, France, and relation with mortality and cognitive or functional decline.","volume":"56","author":"Deschamps","year":"2002","journal-title":"Eur J Clin Nutr"},{"key":"R24-6-20210128","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1520-037X.2003.01046.x","article-title":"Impact of age on definition of standards for ideal weight.","volume":"6","author":"Heiat","year":"2003","journal-title":"Prev Cardiol"},{"key":"R25-6-20210128","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/ajcn\/82.2.435","article-title":".Different modes of weight loss in Alzheimer disease: a prospective study of 395 patients.","volume":"82","author":"Guerin","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"R26-6-20210128","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1001\/archneur.64.3.392","article-title":".Measures of adiposity and dementia risk in elderly persons.","volume":"64","author":"Luchsinger","year":"2007","journal-title":"Arch Neurol"},{"key":"R28-6-20210128","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1212\/WNL.0b013e3181c0d4b6","article-title":".Adiposity indicators and dementia over 32 years in Sweden.","volume":"73","author":"Gustafson","year":"2009","journal-title":"Neurology"},{"key":"R29-6-20210128","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3233\/JAD-2011-110917","article-title":".37 years of body mass index and dementia: observations from the prospective population study of women in Gothenburg, Sweden.","volume":"28","author":"Gustafson","year":"2012","journal-title":"J Alzheimers Dis"},{"key":"R30-6-20210128","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1212\/WNL.56.5.655","article-title":".APOE-epsilon4 is associated with weight loss in women with AD: a population-based study.","volume":"56","author":"Vanhanen","year":"2001","journal-title":"Neurology"},{"key":"R31-6-20210128","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jns.2010.08.036","article-title":"Adiposity hormones and dementia.","volume":"299","author":"Gustafson","year":"2010","journal-title":"J Neurol Sci"},{"key":"R32-6-20210128","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/sj.mp.4001638","article-title":"Body weight is regulated by the brain: a link between feeding and emotion.","volume":"10","author":"Kishi","year":"2005","journal-title":"Mol Psychiatry"},{"key":"R33-6-20210128","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nm1029","article-title":".Adiponectin acts in the brain to decrease body weight.","volume":"10","author":"Qi","year":"2004","journal-title":"Nat Med"},{"key":"R34-6-20210128","first-page":"1029","article-title":"OMalley D, et al..","volume":"33","author":"Harvey","year":"2005","journal-title":"Leptin: a potential cognitive enhancerBiochem Soc Trans"},{"key":"R35-6-20210128","doi-asserted-by":"crossref","first-page":"200","DOI":"10.2174\/157488909789104848","article-title":"Therapeutic approaches of leptin in Alzheimers disease.","volume":"4","author":"Carro","year":"2009","journal-title":"Recent Pat CNS Drug Discov"},{"key":"R36-6-20210128","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1001\/jama.2009.1836","article-title":".Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging.","volume":"302","author":"Lieb","year":"2009","journal-title":"JAMA"},{"key":"R37-6-20210128","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3233\/JAD-122308","article-title":".Sex and ApoE genotype differences in treatment response to two doses of intranasal insulin in adults with mild cognitive impairment or Alzheimers disease.","volume":"35","author":"Claxton","year":"2013","journal-title":"J Alzheimers Dis"},{"key":"R38-6-20210128","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3233\/JAD-121228","article-title":".Sex differences in the associations between lipid levels and incident dementia.","volume":"34","author":"Ancelin","year":"2013","journal-title":"J Alzheimers Dis"},{"key":"R39-6-20210128","first-page":"579","article-title":".Sexual dimorphism in plasma leptin concentration.","volume":"82","author":"Saad","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"R40-6-20210128","first-page":"1293","article-title":".The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure.","volume":"82","author":"Kennedy","year":"1997","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Alzheimer Disease & Associated Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/WAD.0000000000000005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T07:46:47Z","timestamp":1620978407000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00002093-201401000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1097\/wad.0000000000000005","relation":{},"ISSN":["0893-0341"],"issn-type":[{"value":"0893-0341","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}