{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:23:40Z","timestamp":1791044620624,"version":"4.1.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1097\/wad.0b013e31821300bc","type":"journal-article","created":{"date-parts":[[2011,3,29]],"date-time":"2011-03-29T01:55:45Z","timestamp":1301363745000},"page":"8-16","source":"Crossref","is-referenced-by-count":124,"title":["Correlation of Amyloid PET Ligand Florbetapir F 18 Binding With A\u03b2 Aggregation and Neuritic Plaque Deposition in Postmortem Brain Tissue"],"prefix":"10.1097","volume":"26","author":[{"given":"Seok Rye","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Beach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry J.","family":"Bedell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone P.","family":"Zehntner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Krautkramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hank F.","family":"Kung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel M.","family":"Skovronsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Hefti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-2-20210128","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S1474-4422(07)70178-3","article-title":"Research criteria for the diagnosis of Alzheimers disease: revising the NINCDS-ADRDA criteria.","volume":"6","author":"Dubois","year":"2007","journal-title":"Lancet Neurol"},{"key":"R3-2-20210128","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1212\/WNL.41.4.479","article-title":"The consortium to establish a registry for Alzheimers disease (CERAD). Part II: standardization of the neuropathologic assessment of Alzheimers disease.","volume":"41","author":"Mirra","year":"1991","journal-title":"Neurology"},{"key":"R4-2-20210128","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1056\/NEJMra0909142","article-title":"Alzheimers disease.","volume":"362","author":"Querfurth","year":"2010","journal-title":"N Engl J Med"},{"key":"R5-2-20210128","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1126\/science.1132813","article-title":"100 years and counting: prospects for defeating Alzheimers disease.","volume":"314","author":"Roberson","year":"2006","journal-title":"Science"},{"key":"R7-2-20210128","doi-asserted-by":"crossref","first-page":"10598","DOI":"10.1523\/JNEUROSCI.2990-05.2005","article-title":"Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimers disease brain but not in transgenic mouse brain.","volume":"25","author":"Klunk","year":"2005","journal-title":"J Neurosci"},{"key":"R8-2-20210128","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/WCO.0b013e3283168e1a","article-title":"The future of amyloid-beta imaging: a tale of radionuclides and tracer proliferation.","volume":"21","author":"Klunk","year":"2008","journal-title":"Curr Opin Neurol"},{"key":"R9-2-20210128","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.2174\/1381612043384772","article-title":"Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain.","volume":"10","author":"Mathis","year":"2004","journal-title":"Curr Pharm Des"},{"key":"R10-2-20210128","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S1474-4422(08)70001-2","article-title":"Imaging of amyloid beta in Alzheimers disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism.","volume":"7","author":"Rowe","year":"2008","journal-title":"Lancet Neurol"},{"key":"R11-2-20210128","doi-asserted-by":"crossref","first-page":"818","DOI":"10.2967\/jnumed.108.060756","article-title":"Whole-body biodistribution and radiation dosimetry of 18F-GE067: a radioligand for in vivo brain amyloid imaging.","volume":"50","author":"Koole","year":"2009","journal-title":"J Nucl Med"},{"key":"R12-2-20210128","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.2967\/jnumed.109.065284","article-title":"Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain.","volume":"50","author":"Choi","year":"2009","journal-title":"J Nucl Med"},{"key":"R13-2-20210128","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.nucmedbio.2005.06.001","article-title":"F-18 Polyethyleneglycol stilbenes as PET imaging agents targeting Abeta aggregates in the brain.","volume":"32","author":"Zhang","year":"2005","journal-title":"Nucl Med Biol"},{"key":"R14-2-20210128","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.nucmedbio.2006.10.003","article-title":"18F-labeled styrylpyridines as PET agents for amyloid plaque imaging.","volume":"34","author":"Zhang","year":"2007","journal-title":"Nucl Med Biol"},{"key":"R15-2-20210128","doi-asserted-by":"crossref","first-page":"691","DOI":"10.3233\/JAD-2009-1227","article-title":"The neuropathology of older persons with and without dementia from community versus clinic cohorts.","volume":"18","author":"Schneidera","year":"2009","journal-title":"J Alzheimers Dis"},{"key":"R16-2-20210128","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s10561-008-9067-2","article-title":"The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007.","volume":"9","author":"Beach","year":"2008","journal-title":"Cell Tissue Bank"},{"key":"R18-2-20210128","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00005072-199407000-00009","article-title":"Labeling of cerebral amyloid in vivo with a monoclonal antibody.","volume":"53","author":"Walker","year":"1994","journal-title":"J Neuropath Expl Neurol"},{"key":"R19-2-20210128","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1002\/(SICI)1098-1136(19990215)25:4<324::AID-GLIA2>3.0.CO;2-5","article-title":"Occurrence of the diffuse amyloid beta-protein (Abeta) deposits with numerous Abeta-containing glial cells in the cerebral cortex of patients with Alzheimers disease.","volume":"25","author":"Akiyama","year":"1999","journal-title":"Glia"},{"key":"R20-2-20210128","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0003-9861(03)00322-9","article-title":"Y10W beta(1-40) fluorescence reflects epitope exposure in conformers of Alzheimers beta-peptide.","volume":"417","author":"LeVine","year":"2003","journal-title":"Arch Biochem Biophys"},{"key":"R21-2-20210128","doi-asserted-by":"crossref","first-page":"2853","DOI":"10.1073\/pnas.86.8.2853","article-title":"Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.","volume":"86","author":"Grundke-Iqbal","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"R22-2-20210128","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/BF00687398","article-title":"Comparison of four staining methods on the detection of neuritic plaques.","volume":"78","author":"Wisniewski","year":"1989","journal-title":"Acta Neuropathol"},{"key":"R23-2-20210128","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1369\/jhc.2008.950345","article-title":"Synergistic tissue counterstaining and image segmentation techniques for accurate, quantitative immunohistochemistry.","volume":"56","author":"Zehntner","year":"2008","journal-title":"J Histochem Cytochem"},{"key":"R24-2-20210128","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1093\/brain\/awm191","article-title":"PIB is a non-specific imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis.","volume":"130","author":"Lockhart","year":"2007","journal-title":"Brain"},{"key":"R25-2-20210128","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1471-4159.2009.05996.x","article-title":"Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimers disease pathologies.","volume":"109","author":"Thompson","year":"2009","journal-title":"J Neurochem"},{"key":"R26-2-20210128","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/brain\/awn016","article-title":"Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimers disease.","volume":"131","author":"Ikonomovic","year":"2008","journal-title":"Brain"},{"key":"R27-2-20210128","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1001\/archneur.65.10.noc80013","article-title":"Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh compound B.","volume":"65","author":"Leinonen","year":"2008","journal-title":"Arch Neurol"},{"key":"R28-2-20210128","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1212\/WNL.0b013e3181c7da8e","article-title":"In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia.","volume":"74","author":"Burack","year":"2010","journal-title":"Neurology"},{"key":"R29-2-20210128","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1582-4934.2009.00609.x","article-title":"Abeta aggregation and possible implications in Alzheimers disease pathogenesis.","volume":"13","author":"Bharadwaj","year":"2009","journal-title":"J Cell Mol Med"},{"key":"R30-2-20210128","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1146\/annurev.biochem.75.101304.123901","article-title":"Protein misfolding, functional amyloid, and human disease.","volume":"75","author":"Chiti","year":"2006","journal-title":"Annu Rev Biochem"},{"key":"R31-2-20210128","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00401-009-0532-1","article-title":"Classification and basic pathology of Alzheimer disease.","volume":"118","author":"Duyckaerts","year":"2009","journal-title":"Acta Neuropathol"},{"key":"R32-2-20210128","doi-asserted-by":"crossref","first-page":"451","DOI":"10.2119\/2007-00100.Irvine","article-title":"Protein aggregation in the brain: the molecular basis for Alzheimers and Parkinsons diseases.","volume":"14","author":"Irvine","year":"2008","journal-title":"Mol Med"},{"key":"R33-2-20210128","doi-asserted-by":"crossref","first-page":"562","DOI":"10.2174\/156720507783018271","article-title":"Discovery of ADDLtargeting small molecule drugs for Alzheimers disease.","volume":"4","author":"Look","year":"2007","journal-title":"Curr Alzheimer Res"}],"container-title":["Alzheimer Disease &amp; Associated Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00002093-201201000-00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:01:15Z","timestamp":1786042875000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00002093-201201000-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/wad.0b013e31821300bc","relation":{},"ISSN":["0893-0341"],"issn-type":[{"value":"0893-0341","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}