{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:46:49Z","timestamp":1792806409558,"version":"4.5.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,10,8]]},"DOI":"10.1097\/wnr.0b013e3282f03db4","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T18:14:22Z","timestamp":1236190462000},"page":"1543-1546","source":"Crossref","is-referenced-by-count":233,"title":["Localization of \u03b1-synuclein to mitochondria within midbrain of mice"],"prefix":"10.1097","volume":"18","author":[{"given":"Wen-Wei","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Chun","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Min","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-Liang","family":"Zha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie-Shi","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding-Fang","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20210201","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1097\/00005072-199603000-00001","article-title":"Neuropathology of Parkinson's disease","volume":"55","author":"Forno","year":"1996","journal-title":"J Neuropathol Exp Neurol"},{"key":"R2-7-20210201","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.pneurobio.2004.05.002","article-title":"Genes, proteins, and neurotoxins involved in Parkinson's disease","volume":"73","author":"Von Bohlen und Halbach","year":"2004","journal-title":"Progr Neurobiol"},{"key":"R3-7-20210201","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/311467a0","article-title":"Inhibition of monoamine oxidase produces protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine","volume":"311","author":"Heikkila","year":"1984","journal-title":"Nature"},{"key":"R4-7-20210201","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1073\/pnas.82.7.2173","article-title":"Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity","volume":"82","author":"Javitch","year":"1985","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R5-7-20210201","doi-asserted-by":"crossref","first-page":"14524","DOI":"10.1073\/pnas.172514599","article-title":"Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP","volume":"99","author":"Dauer","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R6-7-20210201","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0014-4886(03)00342-X","article-title":"Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP","volume":"186","author":"Song","year":"2004","journal-title":"Exp Neurol"},{"key":"R7-7-20210201","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0002-9440(10)64553-1","article-title":"Alpha-synuclein promotes mitochondrial deficit and oxidative stress","volume":"157","author":"Hsu","year":"2000","journal-title":"Am J Pathol"},{"key":"R8-7-20210201","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1471-4159.1977.tb03920.x","article-title":"Myeline basic protein phosphatase activity in rat brain","volume":"29","author":"McNamara","year":"1997","journal-title":"J Neurochem"},{"key":"R9-7-20210201","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1046\/j.1471-4159.2000.740721.x","article-title":"Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP","volume":"74","author":"Vila","year":"2000","journal-title":"J Neurochem"},{"key":"R10-7-20210201","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0168-0102(00)00095-X","article-title":"The relationship between neurokinin-1 receptor and substance P in the medullary dorsal horn A light and electron microscopic immunohistochemical study in the rat","volume":"36","author":"Li","year":"2000","journal-title":"Neurosci Res"},{"key":"R11-7-20210201","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1080\/07391102.2003.10506918","article-title":"A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders","volume":"21","author":"Uversky","year":"2003","journal-title":"J Biomol Struct Dyn"},{"key":"R12-7-20210201","doi-asserted-by":"crossref","first-page":"6469","DOI":"10.1073\/pnas.95.11.6469","article-title":"Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies","volume":"95","author":"Spillantini","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R13-7-20210201","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1126\/science.276.5321.2045","article-title":"Mutation in the alpha-synuclein gene identified in families with Parkinson's disease","volume":"276","author":"Polymeropoulos","year":"1997","journal-title":"Science"},{"key":"R14-7-20210201","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/ng0298-106","article-title":"Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease","volume":"18","author":"Kruger","year":"1998","journal-title":"Nat Genet"},{"key":"R15-7-20210201","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1126\/science.1067389","article-title":"Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease","volume":"295","author":"Auluck","year":"2002","journal-title":"Science"},{"key":"R16-7-20210201","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/35006074","article-title":"A Drosophila model of Parkinson's disease","volume":"404","author":"Feany","year":"2000","journal-title":"Nature"},{"key":"R17-7-20210201","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1126\/science.287.5456.1265","article-title":"Dopaminergic loss and inclusion body formation in \u03b1-synuclein mice: implications for neurodegenerative disorders","volume":"287","author":"Masliah","year":"2000","journal-title":"Science"},{"key":"R18-7-20210201","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0896-6273(02)00682-7","article-title":"Neuronal \u03b1-synucleinopathy with severe movement disorder in mice expressing A53T human \u03b1-synuclein","volume":"34","author":"Giasson","year":"2002","journal-title":"Neuron"},{"key":"R19-7-20210201","doi-asserted-by":"crossref","first-page":"8968","DOI":"10.1073\/pnas.132197599","article-title":"Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice","volume":"99","author":"Lee","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R20-7-20210201","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.neuint.2004.03.029","article-title":"G209A mutant alpha synuclein expression specifically enhances dopamine induced oxidative damage","volume":"45","author":"Orth","year":"2004","journal-title":"Neurochem Int"},{"key":"R21-7-20210201","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1073\/pnas.0409713102","article-title":"Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiqutin\u2013proteasome system and a-synuclein","volume":"102","author":"Fornai","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"R22-7-20210201","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.nbd.2005.08.018","article-title":"Mice lacking alpha-synuclein are resistant to mitochondrial toxins","volume":"21","author":"Klivenyi","year":"2006","journal-title":"Neurobiol Dis"},{"key":"R23-7-20210201","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.expneurol.2003.12.002","article-title":"Commentary on \u2018Alpha-synuclein and mitochondria: a tangled skein\u2019","volume":"186","author":"Beal","year":"2004","journal-title":"Exp Neurol"}],"container-title":["NeuroReport"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00001756-200710080-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:54:10Z","timestamp":1786038850000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001756-200710080-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10,8]]},"references-count":23,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/wnr.0b013e3282f03db4","relation":{},"ISSN":["0959-4965"],"issn-type":[{"value":"0959-4965","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10,8]]}}}