{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T21:31:40Z","timestamp":1790976700135,"version":"4.1.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,10,24]]},"DOI":"10.1097\/wnr.0b013e328358720b","type":"journal-article","created":{"date-parts":[[2012,8,23]],"date-time":"2012-08-23T10:51:47Z","timestamp":1345719107000},"page":"867-872","source":"Crossref","is-referenced-by-count":23,"title":["Cyclin-dependent kinase 5 immunoreactivity for granulovacuolar degeneration"],"prefix":"10.1097","volume":"23","author":[{"given":"Masahiro","family":"Nakamori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuu","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kurashige","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takemori","family":"Yamawaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayasu","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-1-20210201","doi-asserted-by":"crossref","first-page":"44525","DOI":"10.1074\/jbc.M207426200","article-title":"Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202Thr205 of human tau.","volume":"277","author":"Hashiguchi","year":"2002","journal-title":"J Biol Chem"},{"key":"R2-1-20210201","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S0002-9440(10)65219-4","article-title":"A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimers disease.","volume":"155","author":"Ghoshal","year":"1999","journal-title":"Am J Pathol"},{"key":"R3-1-20210201","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00401-006-0159-4","article-title":"Relation of hippocampal phospho-SAPKJNK granules in Alzheimers disease and tauopathies to granulovacuolar degeneration bodies.","volume":"113","author":"Lagalwar","year":"2007","journal-title":"Acta Neuropathol"},{"key":"R4-1-20210201","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s004010100435","article-title":"The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimers disease.","volume":"103","author":"Leroy","year":"2002","journal-title":"Acta Neuropathol"},{"key":"R5-1-20210201","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/BF00686619","article-title":"A monoclonal antibody that recognizes a phosphorylated epitope in Alzheimer neurofibrillary tangles, neurofilaments and tau proteins immunostains granulovacuolar degeneration.","volume":"73","author":"Dickson","year":"1987","journal-title":"Acta Neuropathol"},{"key":"R6-1-20210201","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00005072-196201000-00007","article-title":"Clinicopathologic significance of granulovacuolar degeneration in Alzheimers disease.","volume":"21","author":"Woodard","year":"1962","journal-title":"J Neuropathol Exp Neurol"},{"key":"R7-1-20210201","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1365-2990.2010.01135.x","article-title":"Granulovacuolar degeneration (GVD) bodies of Alzheimers disease (AD) resemble late-stage autophagic organelles.","volume":"37","author":"Funk","year":"2011","journal-title":"Neuropathol Appl Neurobiol"},{"key":"R8-1-20210201","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.neulet.2010.04.038","article-title":"Immunopositivity for ESCRT-III subunit CHMP2B in granulovacuolar degeneration of neurons in the Alzheimers disease hippocampus.","volume":"477","author":"Yamazaki","year":"2010","journal-title":"Neurosci Lett"},{"key":"R9-1-20210201","doi-asserted-by":"crossref","first-page":"e26996","DOI":"10.1371\/journal.pone.0026996","article-title":"Granulovacuolar degenerations appear in relation to hippocampal phosphorylated tau accumulation in various neurodegenerative disorders.","volume":"6","author":"Yamazaki","year":"2011","journal-title":"PLoS One"},{"key":"R10-1-20210201","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.neulet.2004.07.007","article-title":"Both N-methyl-D-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons.","volume":"368","author":"Kerokoski","year":"2004","journal-title":"Neurosci Lett"},{"key":"R11-1-20210201","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1146\/annurev-cellbio-092910-154023","article-title":"Cyclin-dependent kinases in brain development and disease.","volume":"27","author":"Su","year":"2011","journal-title":"Annu Rev Cell Dev Biol"},{"key":"R12-1-20210201","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0006-8993(96)00523-9","article-title":"Intracellular localization of cyclin-dependent kinase 5 (CDK5) in mouse neuron: CDK5 is located in both nucleus and cytoplasm.","volume":"732","author":"Ino","year":"1996","journal-title":"Brain Res"},{"key":"R13-1-20210201","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1046\/j.1432-1327.2001.02024.x","article-title":"The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimers pathology.","volume":"268","author":"Maccioni","year":"2001","journal-title":"Eur J Biochem"},{"key":"R14-1-20210201","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/jnen\/61.6.557","article-title":"Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles.","volume":"61","author":"Augustinack","year":"2002","journal-title":"J Neuropathol Exp Neurol"},{"key":"R15-1-20210201","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0006-8993(98)00296-0","article-title":"Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimers disease neurofibrillary degeneration.","volume":"797","author":"Pei","year":"1998","journal-title":"Brain Res"},{"key":"R16-1-20210201","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","article-title":"The diagnosis of dementia due to Alzheimers disease: recommendations from the National Institute on Aging-Alzheimers Association workgroups on diagnostic guidelines for Alzheimers disease.","volume":"7","author":"McKhann","year":"2011","journal-title":"Alzheimers Dement"},{"key":"R17-1-20210201","first-page":"132","article-title":"Making the diagnosis of Alzheimers disease. A primer for practicing pathologists.","volume":"117","author":"Mirra","year":"1993","journal-title":"Arch Pathol Lab Med"},{"key":"R18-1-20210201","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes.","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol"},{"key":"R19-1-20210201","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/BF00296544","article-title":"Reexamination of granulovacuolar degeneration.","volume":"82","author":"Okamoto","year":"1991","journal-title":"Acta Neuropathol"},{"key":"R20-1-20210201","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00005072-198807000-00001","article-title":"Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies.","volume":"47","author":"Love","year":"1988","journal-title":"J Neuropathol Exp Neurol"},{"key":"R21-1-20210201","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1440-1789.2009.01017.x","article-title":"Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: their relation to AD common pathology.","volume":"29","author":"Kadokura","year":"2009","journal-title":"Neuropathology"},{"key":"R22-1-20210201","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00401-011-0871-6","article-title":"Stages of granulovacuolar degeneration: their relation to Alzheimers disease and chronic stress response.","volume":"122","author":"Thal","year":"2011","journal-title":"Acta Neuropathol"},{"key":"R23-1-20210201","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF00690970","article-title":"Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of aging and demented patients. A quantitative study.","volume":"42","author":"Ball","year":"1978","journal-title":"Acta Neuropathol"},{"key":"R24-1-20210201","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.neuroscience.2009.06.045","article-title":"Tau hyperphosphorylation affects Smad 23 translocation.","volume":"163","author":"Baig","year":"2009","journal-title":"Neuroscience"},{"key":"R25-1-20210201","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.2353\/ajpath.2009.080814","article-title":"The unfolded protein response is activated in pretangle neurons in Alzheimers disease hippocampus.","volume":"174","author":"Hoozemans","year":"2009","journal-title":"Am J Pathol"}],"container-title":["NeuroReport"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/WNR.0b013e328358720b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T07:21:25Z","timestamp":1620976885000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00001756-201210240-00001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,24]]},"references-count":25,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/wnr.0b013e328358720b","relation":{},"ISSN":["0959-4965"],"issn-type":[{"value":"0959-4965","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10,24]]}}}