{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:33:04Z","timestamp":1773268384547,"version":"3.50.1"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>Peristomal pyoderma gangrenosum (PPG) is a rare complication mainly associated with inflammatory bowel disease. Although it has also been found in patients with an ileostomy with rectal cancer, the best treatment options in this context have not been precisely elucidated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CASE:<\/jats:title>\n            <jats:p>This case report describes the importance of a multidisciplinary treatment approach for a rare case of PPG around a protective ileostomy resulting from rectal cancer.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>Early diagnosis of PPG is imperative to avoid further extension of the lesion. Aggressive management with a multidrug treatment, both topical and systemic, is recommended in severe cases. Close monitoring of the response is necessary, given the variability in the effectiveness of the treatments.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/won.0000000000000657","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T23:22:48Z","timestamp":1593732168000},"page":"403-406","source":"Crossref","is-referenced-by-count":7,"title":["Peristomal Pyoderma Gangrenosum in a Rectal Cancer Patient With an Ileostomy"],"prefix":"10.1097","volume":"47","author":[{"given":"Carlos","family":"Cerd\u00e1n Santacruz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita","family":"Lancharro Berm\u00fadez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Rosario","family":"Caparr\u00f3s Sanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Cerd\u00e1n Miguel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20230928","doi-asserted-by":"crossref","first-page":"e171","DOI":"10.1016\/j.crohns.2012.08.001","article-title":"Risk factors for peristomal pyoderma gangrenosum complicating inflammatory bowel disease","volume":"7","author":"Wu","year":"2013","journal-title":"J Crohns Colitis"},{"key":"R2-20230928","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1001\/archsurg.135.5.564","article-title":"Peristomal pyoderma gangrenosum","volume":"135","author":"Sheldon","year":"2000","journal-title":"Arch Surg"},{"key":"R3-20230928","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1001\/jama.284.12.1546","article-title":"Clinical features and treatment of peristomal pyoderma gangrenosum","volume":"284","author":"Hughes","year":"2000","journal-title":"JAMA"},{"key":"R4-20230928","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.jaad.2017.12.049","article-title":"Diagnosis and management of peristomal pyoderma gangrenosum: a systematic review","volume":"78","author":"Afifi","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"R5-20230928","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1001\/archsurg.1984.01390220064014","article-title":"Pyoderma gangrenosum at the parastomal site in patients with Crohn's disease","volume":"119","author":"McGarity","year":"1984","journal-title":"Arch Surg"},{"key":"R6-20230928","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/S0016-5085(19)35076-0","article-title":"Stomal ulceration associated with pyoderma gangrenosum and chronic ulcerative colitis","volume":"41","author":"Margoles","year":"1961","journal-title":"Gastroenterology"},{"key":"R7-20230928","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1067\/mjd.2000.104515","article-title":"Parastomal pyoderma gangrenosum: clinical features and management","volume":"42","author":"Lyon","year":"2000","journal-title":"J Am Acad Dermatol"},{"key":"R8-20230928","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1007\/s10350-004-0944-x","article-title":"Management of peristomal pyoderma gangrenosum","volume":"48","author":"Kiran","year":"2005","journal-title":"Dis Colon Rectum"},{"key":"R9-20230928","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.jamcollsurg.2007.07.023","article-title":"Management of peristomal pyoderma gangrenosum","volume":"206","author":"Poritz","year":"2008","journal-title":"J Am Coll Surg"},{"key":"R10-20230928","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1007\/BF02052602","article-title":"Parastomal pyoderma gangrenosum in inflammatory bowel disease","volume":"37","author":"Tjandra","year":"1994","journal-title":"Dis Colon Rectum"},{"issue":"10","key":"R11-20230928","doi-asserted-by":"crossref","first-page":"E693","DOI":"10.1111\/ans.14707","article-title":"Peristomal pyoderma gangrenosum: 12-year experience in a single tertiary referral centre","volume":"88","author":"Toh","year":"2018","journal-title":"ANZ J Surg"},{"key":"R12-20230928","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.jaad.2016.05.044","article-title":"Clinical features, causes, treatments and outcomes of peristomal pyoderma gangrenosum (PPG) in 44 patients: The Mayo Clinic experience, 1996 through 2013","volume":"75","author":"Barbosa","year":"2016","journal-title":"J Am Acad Dermatol"},{"key":"R13-20230928","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/DCR.0b013e31819accc6","article-title":"Early diagnosis and early corticosteroid administration improves healing of peristomal pyoderma gangrenosum in inflammatory bowel disease","volume":"52","author":"Funayama","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R14-20230928","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1002\/ibd.20748","article-title":"Adalimumab treatment for peristomal pyoderma gangrenosum associated with Crohn's disease","volume":"15","author":"Alkhouri","year":"2009","journal-title":"Inflamm Bowel Dis"},{"key":"R15-20230928","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1001\/archderm.140.12.1427","article-title":"Mycophenolate mofetil is an effective treatment for peristomal pyoderma gangrenosum","volume":"140","author":"Daniels","year":"2004","journal-title":"Arch Dermatol"},{"key":"R16-20230928","first-page":"407","article-title":"Pyoderma gangrenosum at the colostomy site in a patient with Crohn's disease","volume":"16","author":"Cerd\u00e1n","year":"1994","journal-title":"Coloproctology"},{"key":"R17-20230928","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1159\/000336719","article-title":"Clinical features and management of parastomal pyoderma gangrenosum in inflammatory bowel disease","volume":"85","author":"Uchino","year":"2012","journal-title":"Digestion"},{"key":"R18-20230928","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1463-1318.2004.00607.x","article-title":"Topical tacrolimus (FK506) in the treatment of recalcitrant parastomal pyoderma gangrenosum associated with Crohn's disease: report of two cases","volume":"6","author":"Khurrum Baig","year":"2004","journal-title":"Colorectal Dis"},{"key":"R19-20230928","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1346-8138.2006.00014.x","article-title":"Peristomal pyoderma gangrenosum associated with rectal adenocarcinoma","volume":"1","author":"Sakai","year":"2006","journal-title":"J Dermatol"},{"key":"R20-20230928","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/WON.0000000000000098","article-title":"Surgical management of extensive peristomal pyoderma gangrenosum associated with colon cancer","volume":"42","author":"Ishikawa","year":"2015","journal-title":"J Wound Ostomy Continence Nurs"},{"key":"R21-20230928","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1016\/j.ad.2015.04.022","article-title":"Pioderma gangrenoso periostomal: presentaci\u00f3n de 4 casos y revisi\u00f3n de los factores de riesgo y la respuesta terap\u00e9utica","volume":"107","author":"Turri\u00f3n","year":"2016","journal-title":"Actas Dermatosifiliogr"},{"key":"R22-20230928","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.medcli.2014.11.022","article-title":"Pioderma gangrenoso periostomal asociado a c\u00e1ncer de colon","volume":"144","author":"Miguel","year":"2015","journal-title":"Med Clin"},{"key":"R23-20230928","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.12968\/bjon.2005.14.Sup4.19735","article-title":"Clinical treatment options for peristomal pyoderma gangrenosum","volume":"14","author":"Vujnovich","year":"2005","journal-title":"Br J Nurs"},{"key":"R24-20230928","first-page":"285","article-title":"Pioderma gangrenoso peri-ileostom\u00eda","volume":"106","author":"Cerd\u00e1n","year":"2014","journal-title":"Rev Esp Enferm Dig"},{"key":"R25-20230928","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.gastrohep.2015.05.001","article-title":"Pioderma gangrenoso periestomal en el contexto de enfermedad de Crohn de localizaci\u00f3n col\u00f3nica y perianal compleja","volume":"39","author":"Olmedo","year":"2016","journal-title":"Gastroenterol Hepatol"},{"key":"R26-20230928","doi-asserted-by":"crossref","first-page":"e107","DOI":"10.1016\/j.jaad.2015.05.010","article-title":"Peristomal pyoderma gangrenosum (PG): a simple hydrocolloid dressing technique to promote wound healing","volume":"73","author":"Rodenbeck","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"R27-20230928","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/095466301750163518","article-title":"Topical tacrolimus in the management of peristomal pyoderma gangrenosum","volume":"12","author":"Lyon","year":"2001","journal-title":"J Dermatol Treat"},{"key":"R28-20230928","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-2230.2011.04234.x","article-title":"The use of etanercept in the treatment of peristomal pyoderma gangrenosum","volume":"37","author":"Kim","year":"2012","journal-title":"Clin Exp Dermatol"},{"key":"R29-20230928","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/ajg.2012.42","article-title":"Ustekinumab for peristomal pyoderma gangrenosum","volume":"107","author":"Fahmy","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"R30-20230928","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1038\/ajg.2015.344","article-title":"Refractory peristomal pyoderma gangrenosum successfully treated with intravenous immunoglobulin: a case report","volume":"110","author":"McAllister","year":"2015","journal-title":"Am J Gastroenterol"}],"container-title":["Journal of Wound, Ostomy &amp; Continence Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/WON.0000000000000657","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T01:09:19Z","timestamp":1695863359000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/WON.0000000000000657"}},"subtitle":["A Case Study"],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1097\/won.0000000000000657","relation":{},"ISSN":["1071-5754"],"issn-type":[{"value":"1071-5754","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}