{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:29:30Z","timestamp":1791325770996,"version":"4.3.1"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n            <jats:title>PURPOSE<\/jats:title>\n            <jats:p>The purpose of this study was to examine characteristics of diaper dermatitis (DD) in critically ill patients aged 0 to 24\u00a0months following surgery for congenital heart disease (CHD), the effects of a diaper dermatitis care bundle (DDCB), and factors associated with the development of DD in this population.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>DESIGN<\/jats:title>\n            <jats:p>Nonrandomized comparison cohort study with a historical comparison group.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>SUBJECTS AND SETTING<\/jats:title>\n            <jats:p>Convenience sampling was used to identify children aged 0 to 24\u00a0months undergoing CHD and cared for in a pediatric intensive care unit in central Taiwan (Taichung). The sample comprised 54 participants; 24 were in the historical comparison group and 30 received the DDCB.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS<\/jats:title>\n            <jats:p>The rate of DD from the historical comparison group was compared to that in an intervention group managed with a bundle of interventions used to prevent and manage DD, which includes the routine use of a topical skin protectant. The participants in the historical comparison group received usual care to prevent and manage DD including routine cleansing with a moistened, disposable cloth every 3\u00a0hours and following defecation or urination. The DDCB comprised diaper changes at least every 3\u00a0hours and as needed after soiling, along with the routine application of a dimethicone and sodium hyaluronate-based skin protectant before diaper changes. Both groups were evaluated for use of an antifungal cream when candidiasis was present.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS<\/jats:title>\n            <jats:p>Participants managed with the DDCB have a significantly lower rate of DD than the historical comparison group who received routine care (41.65% vs 6.67%, <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.002). Univariate logistic regression showed an odds ratio of 0.10 (95% confidence interval of 0.019-0.520, <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.006), suggesting that the DDCB acted as a protective factor against the development of DD. Multivariate analysis of the historical comparison group indicated that non-cyanotic heart disease was associated with a lower likelihood of postoperative DD compared to those with cyanotic heart disease (odds ratio\u00a0=\u00a00.01, 95% confidence interval of 0.000-0.946, <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.047).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS<\/jats:title>\n            <jats:p>Managing critically ill patients with a DDCB recovering from cardiac surgery significantly decreased the incidence of DD. We recommend routine use of this type of care bundle for preventing DD in this vulnerable population in all children with CHD, with particular attention being paid to this with cyanotic CHD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/won.0000000000001132","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T07:00:31Z","timestamp":1732604431000},"page":"491-498","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Characteristics of Diaper Dermatitis in Patients Aged 0-24 Months After Congenital Heart Disease and the Effects of a Diaper Dermatitis Care 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