{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:20:51Z","timestamp":1781659251428,"version":"3.54.5"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND<\/jats:title>\n            <jats:p>In this study, we aimed to report our experience with the use of intraoperative transcutaneous laryngeal ultrasonography (TLUSG) to evaluate the vocal cord twitch response during predissection vagus nerve stimulation in thyroid surgeries and examine the reliability of this technique when compared with that of laryngeal twitch palpation (LTP).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>STUDY DESIGN<\/jats:title>\n            <jats:p>The prospective data collection of consecutive patients who underwent open thyroidectomy with intraoperative neuromonitoring (IONM) was reviewed retrospectively. We recorded the electromyographic activity and assessed the vocal cord twitch response on LTP, TLUSG. We compared the accessibility, sensitivity, and specificity of the techniques.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS<\/jats:title>\n            <jats:p>A total of 110 patients (38 men and 72 women) with 134 nerves at risk were enrolled. The vocal cord was assessable by TLUSG in 103 (93.6%) patients and by LTP in 64 (59.1%) patients. Two patients showed negative predissection IONM signal but positive on TLUSG and the presence of laryngeal twitch response confirmed by laryngoscopy. Fourteen patients showed positive IONM signals and presence of the vocal cord twitch response on TLUSG but not on LTP. The sensitivity and specificity were 70.21% and 100%, respectively, for LTP, and those both were 100% for TLUSG. For patients who could be assessed using both techniques, TLUSG had better accuracy than LTP (100% vs 80.33%, p = 0.0005).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS<\/jats:title>\n            <jats:p>The innovative intraoperative application of TLUSG is better for evaluating the laryngeal twitch response than LTP. This technique provides practical troubleshooting guidance for patients with no IONM signals during predissection vagus nerve stimulation.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/xcs.0000000000000053","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T01:01:07Z","timestamp":1649120467000},"page":"359-366","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Transcutaneous Laryngeal Ultrasonography for Assessing Vocal Cord Twitch Response in Thyroid Operation during Predissection Vagus Nerve Stimulation"],"prefix":"10.1097","volume":"234","author":[{"given":"Ting-Chun","family":"Kuo","sequence":"first","affiliation":[{"name":"From the Department of Surgery (Kuo, Chen, Lin, Wu), National Taiwan University Hospital, Taipei, Taiwan"},{"name":"Department of Traumatology (Kuo), National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuen-Yuan","family":"Chen","sequence":"additional","affiliation":[{"name":"From the Department of Surgery (Kuo, Chen, Lin, Wu), National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh-Wen","family":"Lai","sequence":"additional","affiliation":[{"name":"the Department of Surgery, Buddhist Tzu Chi General Hospital, Taipei, Taiwan (Lai)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Chia","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology (Wang), National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Tsan","family":"Lin","sequence":"additional","affiliation":[{"name":"From the Department of Surgery (Kuo, Chen, Lin, Wu), National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Hao","family":"Chang","sequence":"additional","affiliation":[{"name":"the Department of Medical Research, National Taiwan University Hospital and National Taiwan University, Taipei, Taiwan (Chang)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hsun","family":"Wu","sequence":"additional","affiliation":[{"name":"From the Department of Surgery (Kuo, Chen, Lin, Wu), National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,2,15]]},"reference":[{"key":"R1-20250821","first-page":"1167","article-title":"Medicolegal analysis of errors in diagnosis and treatment of surgical endocrine disease.","volume":"114","author":"Kern","year":"1993","journal-title":"Surgery"},{"issue":"suppl 1","key":"R2-20250821","first-page":"S1","article-title":"Electrophysiologic recurrent laryngeal nerve monitoring 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