{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:19:56Z","timestamp":1777475996314,"version":"3.51.4"},"reference-count":53,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1097\/ypg.0000000000000068","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T12:53:01Z","timestamp":1417006381000},"page":"9-20","source":"Crossref","is-referenced-by-count":30,"title":["GRIN2B mediates susceptibility to intelligence quotient and cognitive impairments in developmental dyslexia"],"prefix":"10.1097","volume":"25","author":[{"given":"Sara","family":"Mascheretti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Facoetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Giorda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Beri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Riva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vittoria","family":"Trezzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria R.","family":"Cellino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Marino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-2-20210213","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/sj.ejhg.5200494","article-title":"Pedigree tests of transmission disequilibrium.","volume":"8","author":"Abecasis","year":"2000","journal-title":"Eur J Hum Genet"},{"key":"R4-2-20210213","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.earlhumdev.2003.09.001","article-title":"Effect of antenatal exposure to maternal smoking on behavioural problems and academic achievement in childhood: prospective evidence from a Dutch birth cohort.","volume":"75","author":"Batstra","year":"2003","journal-title":"Early Hum Dev"},{"key":"R5-2-20210213","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1207\/S1532799XSSR0501_3","article-title":"Language phenotype for reading and writing disability: a family approach.","volume":"5","author":"Berninger","year":"2001","journal-title":"Sci Stud Reading"},{"key":"R6-2-20210213","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1046\/j.1440-1754.2002.00039.x","article-title":"Educational outcome at 8 years for children who were born extremely prematurely: a controlled study.","volume":"38","author":"Bowen","year":"2002","journal-title":"J Paediatr Child Health"},{"key":"R9-2-20210213","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0006-8993(98)01243-8","article-title":"Cellular and subcellular localization of the 2B-subunit of the NMDA receptor in the adult rat telencephalon.","volume":"816","author":"Charton","year":"1999","journal-title":"Brain Res"},{"key":"R12-2-20210213","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/00222194040370010501","article-title":"Arithmetic education and learning disabilities in Italy.","volume":"37","author":"Cornoldi","year":"2004","journal-title":"J Learn Disabil"},{"key":"R15-2-20210213","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0142716400000424","article-title":"Awareness of phonological segments and reading ability in Italian children.","volume":"9","author":"Cossu","year":"1988","journal-title":"Appl Psycholinguist"},{"key":"R16-2-20210213","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0959-4388(00)00215-4","article-title":"NMDA receptor subunits: diversity, development and disease.","volume":"11","author":"Cull-Candy","year":"2001","journal-title":"Curr Opin Neurobiol"},{"key":"R20-2-20210213","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1365-3016.1993.tb00604.x","article-title":"Maternal age and cognitive and behavioural outcomes in middle childhood.","volume":"7","author":"Fergusson","year":"1993","journal-title":"Paediatr Perinat Epidemiol"},{"key":"R21-2-20210213","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/1469-7610.00464","article-title":"Maternal age and educational and psychosocial outcomes in early adulthood.","volume":"40","author":"Fergusson","year":"1999","journal-title":"J Child Psychol Psychiatry"},{"key":"R22-2-20210213","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1037\/0012-1649.40.6.935","article-title":"An experimental analysis of dynamic hypotheses about cognitive abilities and achievement from childhood to early adulthood.","volume":"40","author":"Ferrer","year":"2004","journal-title":"Dev Psychol"},{"key":"R23-2-20210213","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1037\/0012-1649.43.6.1460","article-title":"Longitudinal models of developmental dynamics between reading and cognition from childhood to adolescence.","volume":"43","author":"Ferrer","year":"2007","journal-title":"Dev Psychol"},{"key":"R24-2-20210213","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1177\/0956797609354084","article-title":"Uncoupling of reading and IQ over time: empirical evidence for a definition of dyslexia.","volume":"21","author":"Ferrer","year":"2010","journal-title":"Psychol Sci"},{"key":"R25-2-20210213","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s12035-011-8190-4","article-title":"Regulation of long-term plasticity induction by the channel and C-terminal domains of GluN2 subunits.","volume":"44","author":"Fetterolf","year":"2011","journal-title":"Mol Neurobiol"},{"key":"R26-2-20210213","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nrn936","article-title":"Developmental dyslexia: genetic dissection of a complex cognitive trait.","volume":"3","author":"Fisher","year":"2002","journal-title":"Nat Rev Neurosci"},{"key":"R28-2-20210213","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0892-0362(97)00015-9","article-title":"Reading and language in 9- to 12-year olds prenatally exposed to cigarettes and marijuana.","volume":"19","author":"Fried","year":"1997","journal-title":"Neurotoxicol Teratol"},{"key":"R29-2-20210213","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1086\/302193","article-title":"Combined linkage and association sib-pair analysis for quantitative traits.","volume":"64","author":"Fulker","year":"1999","journal-title":"Am J Hum Genet"},{"key":"R30-2-20210213","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1126\/science.1171999","article-title":"Dyslexia: a new synergy between education and cognitive neuroscience.","volume":"325","year":"2009","journal-title":"Science"},{"key":"R31-2-20210213","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1207\/S15326942DN2002_3","article-title":"Genetic and environmental influences on orthographic and phonological skills in children with reading disabilities.","volume":"20","author":"Gayan","year":"2001","journal-title":"Dev Neuropsychol"},{"key":"R32-2-20210213","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0022-0965(02)00181-9","article-title":"Genetic and environmental influences on individual differences in printed word recognition.","volume":"84","author":"Gayan","year":"2003","journal-title":"J Exp Child Psychol"},{"key":"R33-2-20210213","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0028-3932(92)90001-3","article-title":"Reading disability, immune disorders and non-right-handedness: twin and family studies of their relations.","volume":"30","author":"Gilger","year":"1992","journal-title":"Neuropsychologia"},{"key":"R34-2-20210213","first-page":"1","article-title":"Specific dyslexia (congenital word-blindness); a clinical and genetic study.","volume":"65","year":"1950","journal-title":"Acta Psychiatr Neurol Suppl"},{"key":"R35-2-20210213","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1371\/journal.pgen.0010050","article-title":"The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia.","volume":"1","author":"Hannula-Jouppi","year":"2005","journal-title":"PLoS Genet"},{"key":"R36-2-20210213","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1111\/j.1469-7610.2007.01798.x","article-title":"Reading exposure: a (largely) environmental risk factor with environmentally-mediated effects on reading performance in the primary school years.","volume":"48","author":"Harlaar","year":"2007","journal-title":"J Child Psychol Psychiatry"},{"key":"R37-2-20210213","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jcomdis.2005.02.003","article-title":"Socioeconomic status and cultural influences on language.","volume":"38","author":"Hoff","year":"2005","journal-title":"J Commun Disord"},{"key":"R39-2-20210213","first-page":"316","article-title":"Breastfeeding and cognitive development of children: assessment at one year of age.","volume":"21","author":"Hoque","year":"2012","journal-title":"Mymensingh Med J"},{"key":"R40-2-20210213","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3109\/17518429709167360","article-title":"Intellectual status of children with cerebral palsy after elementary education.","volume":"1","author":"Ito","year":"1997","journal-title":"Pediatr Rehabil"},{"key":"R42-2-20210213","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/S1474-4422(08)70165-0","article-title":"NMDA receptors in clinical neurology: excitatory times ahead.","volume":"7","author":"Kalia","year":"2008","journal-title":"Lancet Neurol"},{"key":"R43-2-20210213","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.neuron.2005.04.031","article-title":"Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking.","volume":"46","author":"Kim","year":"2005","journal-title":"Neuron"},{"key":"R45-2-20210213","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nrn2153","article-title":"NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders.","volume":"8","author":"Lau","year":"2007","journal-title":"Nat Rev Neurosci"},{"key":"R46-2-20210213","first-page":"215","article-title":"Multivariate behavioral genetic analysis of achievement and cognitive measures in reading-disabled and control twin pairs.","volume":"70","author":"Light","year":"1998","journal-title":"Hum Biol"},{"key":"R48-2-20210213","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1023\/A:1023438323100","article-title":"Phenotypic and behavioral genetic covariation between elemental cognitive components and scholastic measures.","volume":"33","author":"Luo","year":"2003","journal-title":"Behav Genet"},{"key":"R54-2-20210213","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/jhg.2013.141","article-title":"KIAA0319 and ROBO1: evidence on association with reading and pleiotropic effects on language and mathematics abilities in developmental dyslexia.","volume":"59","author":"Mascheretti","year":"2014","journal-title":"J Hum Genet"},{"key":"R55-2-20210213","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1177\/002221949002300610","article-title":"Family characteristics of children with dyslexia.","volume":"23","year":"1990","journal-title":"J Learn Disabil"},{"key":"R57-2-20210213","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/978-1-4020-8749-3_15","article-title":"Effects of breast-feeding on cognitive function.","volume":"639","author":"Michaelsen","year":"2009","journal-title":"Adv Exp Med Biol"},{"key":"R59-2-20210213","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1146\/annurev.genom.8.080706.092312","article-title":"The genetic lexicon of dyslexia.","volume":"8","author":"Paracchini","year":"2007","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"R60-2-20210213","first-page":"S69","article-title":"Genetics of learning disabilities.","volume":"1","year":"1995","journal-title":"J Child Neurol"},{"key":"R61-2-20210213","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1177\/00222194060390010501","article-title":"Reading skills in early readers: genetic and shared environmental influences.","volume":"39","author":"Petrill","year":"2006","journal-title":"J Learn Disabil"},{"key":"R62-2-20210213","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1037\/0033-2909.131.4.592","article-title":"Generalist genes and learning disabilities.","volume":"131","author":"Plomin","year":"2005","journal-title":"Psychol Bull"},{"key":"R64-2-20210213","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1177\/002221949102400709","article-title":"The irrelevance of IQ to the definition of learning disabilities: some empirical evidence.","volume":"24","author":"Rispens","year":"1991","journal-title":"J Learn Disabil"},{"key":"R66-2-20210213","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1469-7610.2005.01557.x","article-title":"Gene-environment interplay and psychopathology: multiple varieties but real effects.","volume":"47","author":"Rutter","year":"2006","journal-title":"J Child Psychol Psychiatry"},{"key":"R69-2-20210213","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00787-009-0081-0","article-title":"Genetics of developmental dyslexia.","volume":"19","author":"Scerri","year":"2010","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"R73-2-20210213","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/mp.2012.112","article-title":"Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene-environment interactions with childhoodadolescent physical assault.","volume":"18","author":"Sokolowski","year":"2013","journal-title":"Mol Psychiatry"},{"key":"R75-2-20210213","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/1467-9868.00346","article-title":"A direct approach to false discovery rates.","volume":"64","year":"2002","journal-title":"J R Stat Soc"},{"key":"R76-2-20210213","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3102\/00028312039002469","article-title":"Validity of IQ-discrepancy classifications of reading disabilities: a meta-analysis.","volume":"39","author":"Stuebing","year":"2002","journal-title":"Am Educ Res J"},{"key":"R79-2-20210213","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S0022-3565(24)35164-X","article-title":"High-affinity interaction of (des-Tyrosyl)dynorphin A(2-17) with NMDA receptors.","volume":"291","author":"Tang","year":"1999","journal-title":"J Pharmacol Exp Ther"},{"key":"R80-2-20210213","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1542\/peds.2008-2315","article-title":"Functioning at school age of moderately preterm children born at 32 to 36 weeks gestational age.","volume":"124","author":"Van Baar","year":"2009","journal-title":"Pediatrics"},{"key":"R81-2-20210213","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/s10519-008-9201-8","article-title":"A general test for gene-environment interaction in sib pair-based association analysis of quantitative traits.","volume":"38","author":"Van der Sluis","year":"2008","journal-title":"Behav Genet"},{"key":"R82-2-20210213","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s10519-009-9264-1","article-title":"Genetic covariance structure of reading, intelligence and memory in children.","volume":"39","author":"van Leeuwen","year":"2009","journal-title":"Behav Genet"},{"key":"R83-2-20210213","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02197237","article-title":"Cognitive ability and academic achievement in the Colorado Adoption Project: a multivariate genetic analysis of parent-offspring and sibling data.","volume":"25","author":"Wadsworth","year":"1995","journal-title":"Behav Genet"},{"key":"R84-2-20210213","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1023\/B:BEGE.0000023642.34853.cb","article-title":"Genetic and environmental sources of covariance between reading tests used in neuropsychological assessment and IQ subtests.","volume":"34","author":"Wainwright","year":"2004","journal-title":"Behav Genet"},{"key":"R85-2-20210213","doi-asserted-by":"crossref","first-page":"e7486","DOI":"10.1371\/journal.pone.0007486","article-title":"Genetic enhancement of memory and long-term potentiation but not CA1 long-term depression in NR2B transgenic rats.","volume":"4","author":"Wang","year":"2009","journal-title":"PLoS One"},{"key":"R88-2-20210213","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1093\/bioinformatics\/bti529","article-title":"PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data.","volume":"21","author":"Wigginton","year":"2005","journal-title":"Bioinformatics"}],"container-title":["Psychiatric Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/YPG.0000000000000068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:11:00Z","timestamp":1747170660000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00041444-201502000-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1097\/ypg.0000000000000068","relation":{},"ISSN":["0955-8829"],"issn-type":[{"value":"0955-8829","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]}}}