{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:15:51Z","timestamp":1792023351445,"version":"4.4.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1097\/ypg.0b013e3280114a5c","type":"journal-article","created":{"date-parts":[[2007,3,15]],"date-time":"2007-03-15T03:51:49Z","timestamp":1173930709000},"page":"113-116","source":"Crossref","is-referenced-by-count":14,"title":["MeCP2 gene mutation analysis in autistic boys with developmental regression"],"prefix":"10.1097","volume":"17","author":[{"given":"Chun-Yan","family":"Xi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Wei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-Yi","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaru","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao-Hua","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20210213","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/13810","article-title":"Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2","volume":"13","author":"Amir","year":"1999","journal-title":"Nat Genet"},{"key":"R2-9-20210213","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1017\/S0033291700028099","article-title":"Autism as a strongly genetic disorder: evidence from a British twin study","volume":"25","author":"Bailey","year":"1995","journal-title":"Psychol Med"},{"key":"R3-9-20210213","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s00439-002-0786-3","article-title":"Mutation analysis of the coding sequence of the MECP2 gene in infantile autism","volume":"111","author":"Beyer","year":"2002","journal-title":"Hum Genet"},{"key":"R4-9-20210213","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0140-6736(00)02661-1","article-title":"Somatic mutation in MECP2 as a non-fatal neurodevelopmental disorder in males","volume":"356","author":"Clayton-Smith","year":"2000","journal-title":"Lancet"},{"key":"R5-9-20210213","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1044-7431(03)00026-5","article-title":"Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis","volume":"22","author":"Cohen","year":"2003","journal-title":"Mol Cell Neurosci"},{"key":"R6-9-20210213","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1093\/hmg\/10.9.941","article-title":"MECP2 is highly mutated in X-linked mental retardation","volume":"10","author":"Couvert","year":"2001","journal-title":"Hum Mol Genet"},{"key":"R7-9-20210213","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1093\/hmg\/8.7.1253","article-title":"A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3\u2032-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression","volume":"8","author":"Coy","year":"1999","journal-title":"Hum Mol Genet"},{"key":"R8-9-20210213","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1023\/A:1025054610557","article-title":"Epidemiological surveys of autism and other pervasive developmental disorders: an update","volume":"33","author":"Fombonne","year":"2003","journal-title":"J Autism Dev Disord"},{"key":"R9-9-20210213","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0387-7604(87)80072-4","article-title":"Autistic symptoms in Rett syndrome: the first two years according to mother reports","volume":"9","author":"Gillberg","year":"1987","journal-title":"Brain Dev"},{"key":"R10-9-20210213","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/mrdd.20030","article-title":"Rett syndrome: of girls and mice: lessons for regression in autism","volume":"10","author":"Glaze","year":"2004","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"R11-9-20210213","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1023\/B:JADD.0000005998.47370.ef","article-title":"Language and other regression: assessment and timing","volume":"33","author":"Goldberg","year":"2003","journal-title":"J Autism Dev Disord"},{"key":"R12-9-20210213","doi-asserted-by":"crossref","first-page":"E41","DOI":"10.1136\/jmg.37.12.e41","article-title":"Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome","volume":"37","author":"Lam","year":"2000","journal-title":"J Med Genet"},{"key":"R13-9-20210213","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/ajmg.b.10016","article-title":"Absence of MeCP2 mutations in patients from the South Carolina autism project","volume":"117B","author":"Lobo-Menendez","year":"2003","journal-title":"Am J Med Genet"},{"key":"R14-9-20210213","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1469-7610.2004.t01-1-00287.x","article-title":"Regression and word loss in autistic spectrum disorders","volume":"45","author":"Lord","year":"2004","journal-title":"J Child Psychol Psychiatry"},{"key":"R15-9-20210213","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1023\/A:1025066913283","article-title":"Features of autism in Rett syndrome and severe mental retardation","volume":"33","author":"Mount","year":"2003","journal-title":"J Autism Dev Disord"},{"key":"R16-9-20210213","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0014-5793(00)01994-3","article-title":"MECP2 mutation in male patients with non-specific X-linked mental retardation","volume":"481","author":"Orrico","year":"2000","journal-title":"FEBS Lett"},{"key":"R17-9-20210213","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s003350010035","article-title":"Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions","volume":"11","author":"Reichwald","year":"2000","journal-title":"Mamm Genome"},{"key":"R18-9-20210213","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/mrdd.20027","article-title":"Developmental regression in autism spectrum disorders","volume":"10","author":"Rogers","year":"2004","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"R19-9-20210213","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1093\/hmg\/ddh063","article-title":"Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autistic-spectrum disorders","volume":"13","author":"Samaco","year":"2004","journal-title":"Hum Mol Genet"},{"key":"R20-9-20210213","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/ajmg.b.30016","article-title":"MECP2 structural and 3\u2032-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism","volume":"12","author":"Shibayama","year":"2004","journal-title":"Am J Med Genet B Neuropsychiatric Genet"},{"key":"R21-9-20210213","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1203\/00006450-200001000-00006","article-title":"Imprinting, the X-chromosome, and the male brain: explaining sex differences in the liability to autism","volume":"47","author":"Skuse","year":"2000","journal-title":"Pediatr Res"},{"key":"R22-9-20210213","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1023\/A:1026096203946","article-title":"Genetics of autism: overview and new directions","volume":"28","author":"Szatmari","year":"1998","journal-title":"J Autism Dev Disord"},{"key":"R23-9-20210213","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1542\/peds.99.4.560","article-title":"Regression in pervasive developmental disorder: seizures and epileptiform electroencephalogram correlation","volume":"99","author":"Tuchman","year":"1997","journal-title":"Pediatrics"},{"key":"R24-9-20210213","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1212\/WNL.55.8.1188","article-title":"Two affected boys in a Rett syndrome family: clinical and molecular findings","volume":"55","author":"Villard","year":"2000","journal-title":"Neurology"},{"key":"R25-9-20210213","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/sj.ejhg.5200660","article-title":"No mutations in the coding region of the Rett syndrome gene MECP2 in 59 autistic patients","volume":"9","author":"Vourc'h","year":"2001","journal-title":"Eur J Hum Genet"},{"key":"R26-9-20210213","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1136\/jmg.38.4.224","article-title":"Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein","volume":"38","author":"Watson","year":"2001","journal-title":"J Med Genet"},{"key":"R27-9-20210213","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1126\/science.1089071","article-title":"Postnatal neurodevelopmental disorders: meeting at the synapse?","volume":"302","author":"Zoghbi","year":"2003","journal-title":"Science"}],"container-title":["Psychiatric Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/YPG.0b013e3280114a5c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:36:02Z","timestamp":1786034162000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00041444-200704000-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/ypg.0b013e3280114a5c","relation":{},"ISSN":["0955-8829"],"issn-type":[{"value":"0955-8829","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}