{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T05:34:59Z","timestamp":1737005699802,"version":"3.33.0"},"reference-count":64,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Endocrine therapy\u2019s effects may hinder the functional performance and quality of life of women with breast cancer. Physical activity can counteract these effects, but this population does not regularly adopt it. This study aimed to test the impact of a 12-week home-based exercise intervention with a supervised component on the functional performance, quality of life, and physical activity of women with breast cancer undergoing endocrine therapy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Twenty-one women were initially randomized. Three participants were missing at random before the intervention started, leaving 18 with breast cancer stage I to III diagnosis, aged 18 to 75\u00a0years, receiving endocrine therapy, and reporting low to moderate activity levels. The study comprised a weekly online exercise session and, an exercise booklet intervention, and control group. Functional performance, quality of life, and physical activity were assessed. ANOVAs with repeated measures and Bonferroni-adjusted pairwise comparisons were conducted.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>High adherence to program was observed (80%). Significant group-by-time interactions, favoring the intervention group, were found for functional performance\u2014sit-to-stand (F\u00a0=\u00a019.64; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt;\u00a0.001; Eta<jats:sup>2<\/jats:sup>\u00a0=\u00a0.55), arm curl (F\u00a0=\u00a013.01; <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.002; Eta<jats:sup>2<\/jats:sup>\u00a0=\u00a0.45), and timed-up-go (F\u00a0=\u00a012.22; <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.003; Eta<jats:sup>2<\/jats:sup>\u00a0=\u00a0.43); quality of life\u2014insomnia (F\u00a0=\u00a06.05; <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a00.026; Eta<jats:sup>2<\/jats:sup>\u00a0=\u00a0.27) and global health status (F\u00a0=\u00a06.81; <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.020; Eta<jats:sup>2<\/jats:sup>\u00a0=\u00a0.31); and total physical activity (F\u00a0=\u00a05.95; <jats:italic toggle=\"yes\">P<\/jats:italic> =\u00a0.027; Eta<jats:sup>2<\/jats:sup>\u00a0=\u00a0.27).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>The findings suggest that home-based exercise programs might be feasible and improve strength and overall mobility. These programs may contribute to increasing physical activity and quality of life of women with breast cancer. Further studies with larger samples are needed to confirm these findings.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/01.reo.0000000000000382","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T21:02:54Z","timestamp":1736370174000},"page":"26-37","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Supervised Home-Based Exercise Program to Improve Functional Performance in Women With Breast Cancer (Home-Pac): A Randomized Controlled Trial"],"prefix":"10.1097","volume":"43","author":[{"given":"Pedro G.F.","family":"Ramos","sequence":"first","affiliation":[{"name":"Faculdade de Educa\u00e7\u00e3o F\u00edsica e Desporto, Universidade Lus\u00f3fona, Lisboa, Portugal"}]},{"given":"Pedro B.","family":"J\u00fadice","sequence":"additional","affiliation":[{"name":"CIDEFES, Universidade Lus\u00f3fona and CIFID2D, Universidade do Porto"}]},{"given":"Gabriela","family":"Valadas","sequence":"additional","affiliation":[{"name":"Breast Center, University Hospital Center from Algarve, Portim\u00e3o, Portugal"}]},{"given":"Alexandra","family":"Bento","sequence":"additional","affiliation":[{"name":"Breast Center, University Hospital Center from Algarve, Portim\u00e3o, Portugal"}]},{"given":"In\u00eas","family":"Nobre","sequence":"additional","affiliation":[{"name":"Interdisciplinar Center for Human Performance Study, Faculdade de Motricidade Humana, Cruz Quebrada-Dafundo, Portugal"}]},{"given":"Bruno","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Escola Superior de Rio Maior, Instituto Polit\u00e9cnico de Santar\u00e9m, Portugal"}]},{"given":"Eliana V.","family":"Carra\u00e7a","sequence":"additional","affiliation":[{"name":"CIDEFES, Universidade Lus\u00f3fona and CIFID2D, Universidade do 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