{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:33:47Z","timestamp":1772998427831,"version":"3.50.1"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n            <jats:title>Objectives<\/jats:title>\n            <jats:p>The coronavirus disease 2019 (COVID-19) pandemic has affected the availability of healthcare resources, and adjustments to cancer care have been necessary considering the risk of morbidity by COVID-19 and of cancer progression. This study aims to quantify the impact of the COVID-19 pandemic on the care of patients with cancer by comparing a period of 4 months after the outbreak began (2 March 2020) with an equal period from 2019.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Cancer cases of the esophagus, stomach, colon and rectum, pancreas, lung, skin-melanoma, breast, cervix, prostate, non-Hodgkin lymphoma, and leukemia from the Portuguese Oncology Institute of Porto, and diagnosed between 2 March and 1 July 2019 (before COVID-19) and 2020 (after COVID-19) were identified. Those with the first treatment outside the Portuguese Oncology Institute of Porto were excluded. Sociodemographic, clinical and treatment characteristics were obtained from the cancer registry database and clinical files.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The absolute number of new cancer cases decreased nearly 40% after the COVID-19 pandemic (from 1430 to 866). The largest decreases were observed for cervical (\u221274.3%) and prostate (\u221271.7%) cancers. Cases were more often diagnosed at more advanced stages in 2020 (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.001), and the proportion of patients not starting any treatment until 1 July was just under 20% in 2019 and nearly 40% in 2020. The median times from symptoms onset, first medical exam and first appointment to diagnosis, and from diagnosis to first appointment, multidisciplinary tumor board meeting and first treatment were shorter after COVID-19.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>There was a notable overall decrease in cancer diagnoses after COVID-19, with changes in the characteristics of incident cases.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/cej.0000000000000686","type":"journal-article","created":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T01:04:37Z","timestamp":1626397477000},"page":"204-214","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":18,"title":["The impact of the coronavirus disease 2019 pandemic on the diagnosis and treatment of cancer in Northern Portugal"],"prefix":"10.1097","volume":"31","author":[{"given":"Samantha","family":"Morais","sequence":"first","affiliation":[{"name":"EPIUnit, Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas n\u00b0135"},{"name":"Departamento de Ci\u00eancias da Sa\u00fade P\u00fablica e Forenses e Educa\u00e7\u00e3o M\u00e9dica, Faculdade de Medicina da Universidade do Porto, Alameda Professor Hern\u00e2ni Monteiro"}]},{"given":"Lu\u00eds","family":"Antunes","sequence":"additional","affiliation":[{"name":"Grupo de Epidemiologia do Cancro, Centro de Investiga\u00e7\u00e3o do Instituto Portugu\u00eas de Oncologia do Porto, Instituto Portugu\u00eas de Oncologia do Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida"}]},{"given":"J\u00e9ssica","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Grupo de Epidemiologia do Cancro, Centro de Investiga\u00e7\u00e3o do Instituto Portugu\u00eas de Oncologia do Porto, Instituto Portugu\u00eas de Oncologia do Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida"}]},{"given":"Filipa","family":"Fontes","sequence":"additional","affiliation":[{"name":"EPIUnit, Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas n\u00b0135"},{"name":"Departamento de Ci\u00eancias da Sa\u00fade P\u00fablica e Forenses e Educa\u00e7\u00e3o M\u00e9dica, Faculdade de Medicina da Universidade do Porto, Alameda Professor Hern\u00e2ni Monteiro"},{"name":"Servi\u00e7o de Imagem, Instituto Portugu\u00eas de Oncologia do Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida"}]},{"given":"Maria Jos\u00e9","family":"Bento","sequence":"additional","affiliation":[{"name":"Grupo de Epidemiologia do Cancro, Centro de Investiga\u00e7\u00e3o do Instituto Portugu\u00eas de Oncologia do Porto, Instituto Portugu\u00eas de Oncologia do Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida"},{"name":"Departamento de Estudos de Popula\u00e7\u00f5es, Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar da Universidade do Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal"}]},{"given":"Nuno","family":"Lunet","sequence":"additional","affiliation":[{"name":"EPIUnit, Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas n\u00b0135"},{"name":"Departamento de Ci\u00eancias da Sa\u00fade P\u00fablica e Forenses e Educa\u00e7\u00e3o M\u00e9dica, Faculdade de Medicina da Universidade do Porto, Alameda Professor Hern\u00e2ni Monteiro"}]}],"member":"276","published-online":{"date-parts":[[2021,7,8]]},"reference":[{"key":"R1-20250527","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/COC.0000000000000712","article-title":"The impact of the COVID-19 pandemic on cancer patients.","volume":"43","author":"Al-Quteimat","year":"2020","journal-title":"Am J Clin Oncol"},{"key":"R2-20250527","doi-asserted-by":"crossref","first-page":"e936","DOI":"10.1634\/theoncologist.2020-0213","article-title":"A practical approach to the management of cancer patients during the novel coronavirus disease 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