{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T05:17:05Z","timestamp":1769059025002,"version":"3.49.0"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1097\/cej.0b013e32833b48e1","type":"journal-article","created":{"date-parts":[[2010,5,25]],"date-time":"2010-05-25T16:03:23Z","timestamp":1274803403000},"page":"385-392","source":"Crossref","is-referenced-by-count":39,"title":["VEGF and prostatic cancer: a systematic review"],"prefix":"10.1097","volume":"19","author":[{"given":"Francisco","family":"Botelho","sequence":"first","affiliation":[]},{"given":"Francisco","family":"Pina","sequence":"additional","affiliation":[]},{"given":"Nuno","family":"Lunet","sequence":"additional","affiliation":[]}],"member":"276","reference":[{"key":"R1-11-20210128","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.3748\/wjg.14.3879","article-title":"Measurement of circulating levels of VEGF-A, -C, and -D and their receptors, VEGFR-1 and -2 in gastric adenocarcinoma","volume":"14","author":"Al-Moundhri","year":"2008","journal-title":"World J Gastroenterol"},{"key":"R2-11-20210128","doi-asserted-by":"crossref","first-page":"451","DOI":"10.7326\/0003-4819-147-7-200710020-00003","article-title":"Serum and biliary insulin-like growth factor I and vascular endothelial growth factor in determining the cause of obstructive cholestasis","volume":"147","author":"Alvaro","year":"2007","journal-title":"Ann Intern Med"},{"key":"R3-11-20210128","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1038\/sj.bjc.6600956","article-title":"Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients","volume":"88","author":"Bachelot","year":"2003","journal-title":"Br J Cancer"},{"key":"R4-11-20210128","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/bjc.1998.158","article-title":"Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology","volume":"77","author":"Banks","year":"1998","journal-title":"Br J Cancer"},{"key":"R6-11-20210128","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1160\/TH03-11-0679","article-title":"Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma","volume":"92","author":"Caine","year":"2004a","journal-title":"Thromb Haemost"},{"key":"R7-11-20210128","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1080\/07853890410026098","article-title":"Platelet-derived VEGF, Flt-1, angiopoietin-1 and P-selectin in breast and prostate cancer: further evidence for a role of platelets in tumour angiogenesis","volume":"36","author":"Caine","year":"2004b","journal-title":"Ann Med"},{"key":"R8-11-20210128","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/MPA.0b013e318164548a","article-title":"Serum vascular endothelial growth factor\/soluble vascular endothelial growth factor receptor 1 ratio is an independent prognostic marker in pancreatic cancer","volume":"37","author":"Chang","year":"2008","journal-title":"Pancreas"},{"key":"R9-11-20210128","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0090-4295(99)00167-3","article-title":"Plasma levels of vascular endothelial growth factor are increased in patients with metastatic prostate cancer","volume":"54","author":"Duque","year":"1999","journal-title":"Urology"},{"key":"R11-11-20210128","doi-asserted-by":"crossref","first-page":"4368","DOI":"10.1200\/JCO.2002.10.088","article-title":"Vascular permeability factor\/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy","volume":"20","author":"Dvorak","year":"2002","journal-title":"J Clin Oncol"},{"key":"R12-11-20210128","first-page":"57","article-title":"Clinical significance of vascular endothelial growth factor (VEGF) in sera of patients with pediatric malignancies","volume":"16","author":"El-Houseini","year":"2004","journal-title":"J Egypt Natl Canc Inst"},{"key":"R13-11-20210128","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1016\/S0022-5347(01)64775-X","article-title":"Vascular endothelial growth factor (VEGF) expression in human prostate cancer: in situ and in vitro expression of VEGF by human prostate cancer cells","volume":"157","author":"Ferrer","year":"1997","journal-title":"J Urol"},{"key":"R14-11-20210128","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/376066a0","article-title":"Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium","volume":"376","author":"Fong","year":"1995","journal-title":"Nature"},{"key":"R15-11-20210128","first-page":"4140","article-title":"Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis","volume":"55","author":"Freeman","year":"1995","journal-title":"Cancer Res"},{"key":"R17-11-20210128","first-page":"3147","article-title":"Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: clinical evidence of platelet scavenging?","volume":"6","author":"George","year":"2000","journal-title":"Clin Cancer Res"},{"key":"R18-11-20210128","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.urology.2003.09.059","article-title":"Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer","volume":"63","author":"George","year":"2004","journal-title":"Urology"},{"key":"R19-11-20210128","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1464-410X.2006.06177.x","article-title":"Using prostate-specific antigen screening and nomograms to assess risk and predict outcomes in the management of prostate cancer","volume":"98","author":"Hammerer","year":"2006","journal-title":"BJU Int"},{"key":"R20-11-20210128","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00008469-200206000-00008","article-title":"Prognostic importance of serum vascular endothelial growth factor in relation to platelet and leukocyte counts in human renal cell carcinoma","volume":"11","author":"Jacobsen","year":"2002","journal-title":"Eur J Cancer Prev"},{"key":"R22-11-20210128","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3322\/CA.2007.0010","article-title":"Cancer statistics, 2008","volume":"58","author":"Jemal","year":"2008","journal-title":"CA Cancer J Clin"},{"key":"R25-11-20210128","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1046\/j.1464-410x.2000.00432.x","article-title":"Elevated serum vascular endothelial growth factor in patients with hormone-escaped prostate cancer","volume":"85","author":"Jones","year":"2000","journal-title":"BJU Int"},{"key":"R26-11-20210128","first-page":"1279","article-title":"Preoperative serum vascular endothelial growth factor can predict stage in colorectal cancer","volume":"4","author":"Kumar","year":"1998","journal-title":"Clin Cancer Res"},{"key":"R27-11-20210128","first-page":"2295","article-title":"Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor\/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers","volume":"6","author":"Kuniyasu","year":"2000","journal-title":"Clin Cancer Res"},{"key":"R28-11-20210128","first-page":"1060","article-title":"Clinical significance of quantitative analysis of serum VEGF, CD44\u2009s, and MMP-3 protein in nasopharyngeal carcinoma","volume":"23","author":"Li","year":"2004","journal-title":"Ai Zheng"},{"key":"R29-11-20210128","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jama.282.11.1061","article-title":"Empirical evidence of design-related bias in studies of diagnostic tests","volume":"282","author":"Lijmer","year":"1999","journal-title":"JAMA"},{"key":"R30-11-20210128","first-page":"51","article-title":"Biomarkers for early prostate cancer detection","volume":"60","author":"Margreiter","year":"2008","journal-title":"Minerva Urol Nefrol"},{"key":"R32-11-20210128","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/jcb.10772","article-title":"Angiogenesis and prostate cancer tumor growth","volume":"91","author":"Nicholson","year":"2004","journal-title":"J Cell Biochem"},{"key":"R33-11-20210128","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000092583","article-title":"Should men with serum prostate-specific antigen \u22644\u2009ng\/ml and normal digital rectal examination undergo a prostate biopsy? A literature review","volume":"70","author":"Pepe","year":"2006","journal-title":"Oncology"},{"key":"R34-11-20210128","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.urology.2005.03.082","article-title":"Serum levels of vascular endothelial growth factor in patients undergoing prostate biopsy for suspicion of prostate cancer","volume":"66","author":"Peyromaure","year":"2005","journal-title":"Urology"},{"key":"R35-11-20210128","first-page":"27","article-title":"Circulating endothelial cells, endothelial precursors, VEGF and bFGF concentrations in patients with acute leukemias, lymphomas and myelomas","volume":"113","author":"Poreba","year":"2005","journal-title":"Pol Arch Med Wewn"},{"key":"R37-11-20210128","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1503\/cmaj.050090","article-title":"Evidence of bias and variation in diagnostic accuracy studies","volume":"174","author":"Rutjes","year":"2006","journal-title":"Can Med Assoc J"},{"key":"R39-11-20210128","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1023\/A:1016611230747","article-title":"Platelets and vascular endothelial growth factor (VEGF): a morphological and functional study","volume":"4","author":"Salgado","year":"2001","journal-title":"Angiogenesis"},{"key":"R40-11-20210128","first-page":"1286","article-title":"The search for better markers for prostate cancer than prostate-specific antigen","volume":"150","author":"Schenk-Braat","year":"2006","journal-title":"Ned Tijdschr Geneeskd"},{"key":"R42-11-20210128","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/978-3-540-69297-3_16","article-title":"Review of diagnostic markers for prostate cancer","volume":"181","author":"Schroder","year":"2009","journal-title":"Recent Results Cancer Res"},{"key":"R43-11-20210128","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1200\/JCO.2004.09.142","article-title":"Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy","volume":"22","author":"Shariat","year":"2004","journal-title":"J Clin Oncol"},{"key":"R44-11-20210128","first-page":"68","article-title":"Clinical significance of serum vascular endothelial growth factor and interleukin-6 in multiple myeloma","volume":"30","author":"Shen","year":"2005","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"key":"R46-11-20210128","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1503\/cmaj.060955","article-title":"Prostate-specific antigen in the early detection of prostate cancer","volume":"176","author":"Thompson","year":"2007","journal-title":"Can Med Assoc J"},{"key":"R47-11-20210128","first-page":"17","article-title":"Vascular endothelial growth factor and insulin-like-growth factors in prostate cancer","volume":"1","author":"Trapeznikova","year":"2004","journal-title":"Urologiia"},{"key":"R48-11-20210128","first-page":"14","article-title":"Vascular endothelial growth factor in patients with prostate cancer and benign prostatic hyperplasia","volume":"5","author":"Trapeznikova","year":"2005","journal-title":"Vestn Ross Akad Med Nauk"},{"key":"R49-11-20210128","first-page":"1454","article-title":"Clinical significance of plasma D-dimer levels and serum VEGF levels in patients with hepatocellular carcinoma","volume":"51","author":"Tseng","year":"2004","journal-title":"Hepatogastroenterology"},{"key":"R50-11-20210128","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1046\/j.1464-410x.1999.00363.x","article-title":"Angiogenic peptides in prostatic disease","volume":"84","author":"Walsh","year":"1999","journal-title":"BJU Int"},{"key":"R51-11-20210128","first-page":"821","article-title":"Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients","volume":"2","author":"Yamamoto","year":"1996","journal-title":"Clin Cancer Res"}],"container-title":["European Journal of Cancer Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/CEJ.0b013e32833b48e1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T19:48:51Z","timestamp":1621885731000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00008469-201009000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/cej.0b013e32833b48e1","relation":{},"ISSN":["0959-8278"],"issn-type":[{"value":"0959-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}