{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T05:41:54Z","timestamp":1770961314016,"version":"3.50.1"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To evaluate the combined effects of inherent ocular aberrations and induced aberrations with a multifocal soft contact lens (MFCL) after 15 days of lens wear in presbyopic participants and their influence on visual performance at distance and near under high and low contrast conditions.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Forty presbyopic participants (mean age, 48.7\u00b13.4) presenting a mean addition of 1.53\u00b10.58 D were fitted with Biofinity Multifocal (CooperVision) and included in the study. Measurements comprised distance and near monocular high (100%) and low contrast (10%) logMAR visual acuity (VA). Ocular aberrations were obtained with Hartmann\u2013Shack aberrometer (IRX3, Imagine Eyes) and analyzed for 2 mm and maximum round natural pupil.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Distance VA was significantly higher in dominant eye, whereas near VA was significantly better in the non-dominant eye (<jats:italic toggle=\"yes\">P<\/jats:italic>&lt;0.05 in all conditions). For a 2-mm pupil in the dominant eye fitted with MFCL, spherical-like aberration significantly increased (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.027) so as higher-order aberrations (HOA) (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.002). A significant increase was also observed in spherical-like aberrations (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.001), coma-like aberrations (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.006) and HOA (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.004) in non-dominant eye. For the maximum round natural pupil size, a significant decrease in vertical coma was observed (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.018) in dominant eye, whereas a significant increase in spherical-like (<jats:italic toggle=\"yes\">P<\/jats:italic>&lt;0.001) and coma-like aberrations (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.007) was observed in non-dominant eye. A negative significant correlation was found between vertical coma and high contrast VA (Rho=\u22120.405, <jats:italic toggle=\"yes\">P<\/jats:italic>=0.011) in dominant eye; whereas in non-dominant eye, a significant correlation was found between induced secondary astigmatism and distance VA under high (Rho=0.556, <jats:italic toggle=\"yes\">P<\/jats:italic>&lt;0.001) and low contrast (Rho=0.448, <jats:italic toggle=\"yes\">P<\/jats:italic>=0.005).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>On-eye visual performance of MFSCL is dependent on the high-order aberrations induced by dominant and non-dominant design coupled with the wearer's inherent aberrations.<\/jats:p>\n          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