{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T19:54:47Z","timestamp":1768679687623,"version":"3.49.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.09).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/ijg.0000000000000326","type":"journal-article","created":{"date-parts":[[2015,9,23]],"date-time":"2015-09-23T03:14:25Z","timestamp":1442978065000},"page":"e576-e580","source":"Crossref","is-referenced-by-count":7,"title":["Secondary Epiretinal Membrane After Trabeculectomy"],"prefix":"10.1097","volume":"25","author":[{"given":"Lu\u00edsa","family":"Vieira","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"}]},{"given":"Ana","family":"Cabugueira","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"}]},{"given":"B\u00e1rbara","family":"Borges","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"}]},{"given":"Vanessa","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"}]},{"given":"Manuel","family":"Noronha","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"}]},{"given":"Luis","family":"Abeg\u00e3o Pinto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"},{"name":"Institute of Pharmacology and Neurosciences, Faculty of Medicine, University of Lisbon"}]},{"given":"Maria","family":"Reina","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"}]},{"given":"Marco","family":"Dutra Medeiros","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Central Lisbon Hospital Center"},{"name":"NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal"}]}],"member":"276","reference":[{"key":"R1-20230912","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/BF02720906","article-title":"Beitrage zur normalen und pathologischen anatomy des auges [Contributions to the normal and pathological anatomy of the eye]","volume":"11","author":"Iwanoff","year":"1865","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R2-20230912","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1097\/IAE.0b013e31822a8fec","article-title":"Biomicroscopy versus optical coherence tomography screening of epiretinal membranes in patients undergoing cataract surgery","volume":"32","author":"Milani","year":"2012","journal-title":"Retina"},{"key":"R3-20230912","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ajo.2005.03.032","article-title":"Prevalence and associations of epiretinal membranes in the visual impairment project","volume":"140","author":"McCarty","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"R4-20230912","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/00006982-200402000-00009","article-title":"Comparison of epiretinal membranes of differing pathogenesis using optical coherence tomography","volume":"24","author":"Mori","year":"2004","journal-title":"Retina"},{"key":"R5-20230912","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0161-6420(02)01443-4","article-title":"Five-year cumulative incidence and progression of epiretinal membranes: the Blue Mountains Eye Study","volume":"110","author":"Fraser-Bell","year":"2003","journal-title":"Ophthalmology"},{"key":"R6-20230912","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1167\/iovs.03-1295","article-title":"Los Angeles Latino Eye Study. 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