{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T02:14:04Z","timestamp":1774491244587,"version":"3.50.1"},"reference-count":77,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","license":[{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Pain","PAIN"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Chronic pelvic pain (CPP), despite its high prevalence, is still relatively poorly understood mechanistically. This study, as part of the Translational Research in Pelvic Pain (TRiPP) project, has used a full quantitative sensory testing (QST) paradigm to profile n = 85 women with and without CPP (endometriosis or bladder pain specifically). We used the foot as a control site and abdomen as the test site. Across 5 diagnostically determined subgroups, we found features which are common across different aetiologies, eg, gain of function in pressure pain threshold (PPT) when assessing responses from the lower abdomen or pelvis (referred pain site). However, disease-specific phenotypes were also identified, eg, greater mechanical allodynia in endometriosis, despite there being large heterogeneities within diagnostic groups. The most common QST sensory phenotype was mechanical hyperalgesia (&gt;50% across all the groups). A \u201chealthy\u2019 sensory phenotype was seen in &lt;7% of CPP participants. Specific QST measures correlated with sensory symptoms assessed by the painDETECT questionnaire (pressure-evoked pain [painDETECT] and PPT [QST] [\n                    <jats:italic toggle=\"yes\">r<\/jats:italic>\n                    = 0.47,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001]; mechanical hyperalgesia (painDETECT) and mechanical pain sensitivity [MPS from QST] [\n                    <jats:italic toggle=\"yes\">r<\/jats:italic>\n                    = 0.38,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.009]). The data suggest that participants with CPP are sensitive to both deep tissue and cutaneous inputs, suggesting that central mechanisms may be important in this cohort. We also see phenotypes such as thermal hyperalgesia, which may be the result of peripheral mechanisms, such as irritable nociceptors. This highlights the importance of stratifying patients into clinically meaningful phenotypes, which may have implications for the development of better therapeutic strategies for CPP.\n                  <\/jats:p>","DOI":"10.1097\/j.pain.0000000000002955","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T13:10:15Z","timestamp":1686229815000},"page":"2528-2539","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":18,"title":["Comprehensive quantitative sensory testing shows altered sensory function in women with chronic pelvic pain: results from the Translational Research in Pelvic Pain (TRiPP) Study"],"prefix":"10.1097","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0818-1240","authenticated-orcid":false,"given":"Lydia","family":"Coxon","sequence":"first","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Jan","family":"Vollert","sequence":"additional","affiliation":[{"name":"University Hospital Muenster, Muenster, Germany"},{"name":"Heidelberg University, Mannheim, Germany"},{"name":"Pain Research, Department of Surgery and Cancer, Imperial College London, London, United Kingdom"},{"name":"Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany"}]},{"given":"Danielle","family":"Perro","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Claire E.","family":"Lunde","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"},{"name":"Biobehavioral Pain Innovations Lab, Department of Psychiatry & Behavioral Sciences, Boston Children's Hospital, Boston, MA, United States"},{"name":"Pain and Affective Neuroscience Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA, United States"}]},{"given":"Joana","family":"Ferreira-Gomes","sequence":"additional","affiliation":[{"name":"IBMC\/I3S, Faculty of Medicine of Porto & Hospital S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Ana","family":"Charrua","sequence":"additional","affiliation":[{"name":"IBMC\/I3S, Faculty of Medicine of Porto & Hospital S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Pedro","family":"Abreu-Mendes","sequence":"additional","affiliation":[{"name":"IBMC\/I3S, Faculty of Medicine of Porto & Hospital S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Michal","family":"Krassowski","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Judy","family":"Birch","sequence":"additional","affiliation":[{"name":"Pelvic Pain Support Network, Poole, United Kingdom"}]},{"given":"Jane","family":"Meijlink","sequence":"additional","affiliation":[{"name":"International Painful Bladder Foundation, Naarden, the Netherlands"}]},{"given":"Lone","family":"Hummelshoj","sequence":"additional","affiliation":[{"name":"Endometriosis.org, London, United Kingdom"}]},{"given":"Anja","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Bayer AG, Research & Development, Pharmaceuticals, Berlin, Germany"}]},{"given":"Qasim","family":"Aziz","sequence":"additional","affiliation":[{"name":"Queen Mary University of London, London, United Kingdom"}]},{"given":"Lars","family":"Arendt-Nielsen","sequence":"additional","affiliation":[{"name":"Center for Neuroplasticity and Pain (CNAP), SMI, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark"},{"name":"Department of Medical Gastroenterology, Mech-Sense, Aalborg University Hospital, Aalborg, Denmark"}]},{"given":"Esther","family":"Pogatzki-Zahn","sequence":"additional","affiliation":[{"name":"University Hospital Muenster, Muenster, Germany"}]},{"given":"Emma","family":"Evans","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Lysia","family":"Demetriou","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Stephen B.","family":"McMahon","sequence":"additional","affiliation":[{"name":"Formerly of Neurorestoration Group, Wolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom"}]},{"given":"Stacey A.","family":"Missmer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, MI, United States"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States"},{"name":"Division of Adolescent and Young Adult Medicine, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States"}]},{"given":"Christian M.","family":"Becker","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Krina T.","family":"Zondervan","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]},{"given":"Andrew W.","family":"Horne","sequence":"additional","affiliation":[{"name":"University of Edinburgh, Edinburgh, United Kingdom"}]},{"given":"Francisco","family":"Cruz","sequence":"additional","affiliation":[{"name":"IBMC\/I3S, Faculty of Medicine of Porto & Hospital S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Christine B.","family":"Sieberg","sequence":"additional","affiliation":[{"name":"Biobehavioral Pain Innovations Lab, Department of Psychiatry & Behavioral Sciences, Boston Children's Hospital, Boston, MA, United States"},{"name":"Pain and Affective Neuroscience Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA, United States"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, MA, United States"}]},{"given":"Rolf-Detlef","family":"Treede","sequence":"additional","affiliation":[{"name":"Heidelberg University, Mannheim, Germany"}]},{"given":"Jens","family":"Nagel","sequence":"additional","affiliation":[{"name":"Bayer AG, Research & Development, Pharmaceuticals, Wuppertal, Germany"}]},{"given":"Katy","family":"Vincent","sequence":"additional","affiliation":[{"name":"Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom"}]}],"member":"276","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"R1-20251216","doi-asserted-by":"crossref","first-page":"E141","DOI":"10.36076\/ppj.2014\/17\/E141","article-title":"Prevalence of chronic pelvic pain among women: an updated review","volume":"17","author":"Ahangari","year":"2014","journal-title":"Pain Phys"},{"key":"R2-20251216","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1001\/jama.2010.1913","article-title":"Management of chronic prostatitis\/chronic pelvic pain syndrome: a systematic review and network meta-analysis","volume":"305","author":"Anothaisintawee","year":"2011","journal-title":"JAMA"},{"key":"R3-20251216","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1097\/AOG.0b013e3182a7e1f5","article-title":"Increased pressure pain sensitivity in women with chronic pelvic pain","volume":"122","author":"As-Sanie","year":"2013","journal-title":"Obstet Gynecol"},{"key":"R4-20251216","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1097\/j.pain.0000000000001184","article-title":"Recently introduced IASP definition of \u2018nociplastic pain\u2019 needs better formulation","volume":"159","author":"Aydede","year":"2018","journal-title":"PAIN"},{"key":"R5-20251216","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/j.pain.0000000000001362","article-title":"The IASP classification of chronic pain for ICD-11: chronic secondary visceral pain","volume":"160","author":"Aziz","year":"2019","journal-title":"PAIN"},{"key":"R6-20251216","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S1474-4422(10)70143-5","article-title":"Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment","volume":"9","author":"Baron","year":"2010","journal-title":"Lancet Neurol"},{"key":"R7-20251216","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41582-022-00741-7","article-title":"Maximizing treatment efficacy through patient stratification in neuropathic pain trials","volume":"19","author":"Baron","year":"2022","journal-title":"Nat Rev Neurol"},{"key":"R8-20251216","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/j.pain.0000000000000753","article-title":"Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles","volume":"158","author":"Baron","year":"2017","journal-title":"PAIN"},{"key":"R9-20251216","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pain.2009.06.001","article-title":"A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: differences in demographic data and sensory symptoms","volume":"146","author":"Baron","year":"2009","journal-title":"PAIN"},{"key":"R10-20251216","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0304-3959(01)00438-9","article-title":"Neurogenic hyperalgesia versus painful hypoalgesia: two distinct mechanisms of neuropathic pain","volume":"96","author":"Baumg\u00e4rtner","year":"2022","journal-title":"PAIN"},{"key":"R11-20251216","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/s41585-018-0135-5","article-title":"Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network","volume":"16","author":"Clemens","year":"2019","journal-title":"Nat Rev Urol"},{"key":"R12-20251216","doi-asserted-by":"crossref","first-page":"743812","DOI":"10.3389\/fpain.2021.743812","article-title":"Is there a neuropathic-like component to endometriosis-associated pain? Results from a large cohort questionnaire study","volume":"2","author":"Coxon","year":"2021","journal-title":"Front Pain Res"},{"key":"R13-20251216","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/pme.12230","article-title":"Can quantitative sensory testing move us closer to mechanism-based pain management?","volume":"15","author":"Cruz-Almeida","year":"2014","journal-title":"Pain Med"},{"key":"R14-20251216","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1016\/j.pain.2014.08.014","article-title":"The effect of oxcarbazepine in peripheral neuropathic pain depends on pain phenotype: A randomised, double-blind, placebo-controlled phenotype-stratified study","volume":"155","author":"Demant","year":"2014","journal-title":"PAIN"},{"key":"R15-20251216","article-title":"Deep phenotyping of women with endometriosis-associated pain and bladder pain syndrome: the TRiPP (Translational Research in Pelvic Pain) study protocol","author":"Demetriou","year":"2022","journal-title":"medRxiv"},{"key":"R16-20251216","doi-asserted-by":"crossref","DOI":"10.3389\/frph.2023.1140857","article-title":"Clinical profiling of subgroups of women with chronic pelvic pain","volume":"5","author":"Demetriou","year":"2023","journal-title":"Frontiers in Reproductive Health"},{"key":"R17-20251216","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1093\/humrep\/det457","article-title":"ESHRE guideline: management of women with endometriosis","volume":"29","author":"Dunselman","year":"2014","journal-title":"Hum Reprod"},{"key":"R18-20251216","doi-asserted-by":"crossref","first-page":"e389","DOI":"10.1212\/WNL.0000000000012229","article-title":"Contralateral sensory and pain perception changes in patients with unilateral neuropathy","volume":"97","author":"Enax-Krumova","year":"2021","journal-title":"Neurology"},{"key":"R19-20251216","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0889-8545(05)70302-8","article-title":"Epidemiology of endometriosis","volume":"24","author":"Eskenazi","year":"1997","journal-title":"Obstet Gynecol Clin North Am"},{"key":"R20-20251216","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1006\/nbdi.1998.0204","article-title":"Postherpetic neuralgia: irritable nociceptors and deafferentation","volume":"5","author":"Fields","year":"1998","journal-title":"Neurobiol Dis"},{"key":"R21-20251216","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1016\/S0140-6736(21)00392-5","article-title":"Nociplastic pain: towards an understanding of prevalent pain conditions","volume":"397","author":"Fitzcharles","year":"2021","journal-title":"Lancet"},{"key":"R22-20251216","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1097\/EJA.0000000000000319","article-title":"Chronic postsurgical pain in Europe: an observational study","volume":"32","author":"Fletcher","year":"2015","journal-title":"Eur J Anaesthesiol"},{"key":"R23-20251216","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1185\/030079906X132488","article-title":"painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain","volume":"22","author":"Freynhagen","year":"2006","journal-title":"Curr Med Res Opin"},{"key":"R24-20251216","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1185\/03007995.2016.1157460","article-title":"The painDETECT project\u2014far more than a screening tool on neuropathic pain","volume":"32","author":"Freynhagen","year":"2016","journal-title":"Curr Med Res Opin"},{"key":"R25-20251216","first-page":"35","article-title":"An update on treatment options for interstitial cystitis","volume":"19","author":"Garzon","year":"2020","journal-title":"Przeglad Menopauzalny"},{"key":"R26-20251216","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/AJP.0000000000000582","article-title":"Do we measure what patients feel?: an analysis of correspondence between somatosensory modalities upon quantitative sensory testing and self-reported pain experience","volume":"34","author":"Gierthm\u00fchlen","year":"2018","journal-title":"Clin J Pain"},{"key":"R27-20251216","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1097\/j.pain.0000000000002501","article-title":"Association of sensory phenotype with quality of life, functionality, and emotional well-being in patients suffering from neuropathic pain","volume":"163","author":"Gierthm\u00fchlen","year":"2022","journal-title":"PAIN"},{"key":"R28-20251216","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/aogs.13508","article-title":"Reduced pain thresholds and signs of sensitization in women with persistent pelvic pain and suspected endometriosis","volume":"98","author":"Grundstr\u00f6m","year":"2019","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R29-20251216","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.pain.2010.07.031","article-title":"NeuPSIG guidelines on neuropathic pain assessment","volume":"152","author":"Haanp\u00e4\u00e4","year":"2011","journal-title":"PAIN"},{"key":"R30-20251216","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1097\/j.pain.0000000000001505","article-title":"Quantitative assessment of nonpelvic pressure pain sensitivity in urologic chronic pelvic pain syndrome: a MAPP Research Network study","volume":"160","author":"Harte","year":"2019","journal-title":"PAIN"},{"key":"R31-20251216","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1097\/j.pain.0000000000001826","article-title":"Dysmenorrhea subtypes exhibit differential quantitative sensory assessment profiles","volume":"161","author":"Hellman","year":"2020","journal-title":"PAIN"},{"key":"R32-20251216","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.joca.2013.06.023","article-title":"Neuropathic pain symptoms on the modified painDETECT correlate with signs of central sensitization in knee osteoarthritis","volume":"21","author":"Hochman","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"R33-20251216","doi-asserted-by":"crossref","first-page":"291","DOI":"10.36076\/ppj.2013\/16\/291","article-title":"Central sensitization in urogynecological chronic pelvic pain: a systematic literature review","volume":"16","author":"Kaya","year":"2013","journal-title":"Pain Physician"},{"key":"R34-20251216","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1093\/humrep\/dei135","article-title":"ESHRE guideline for the diagnosis and treatment of endometriosis","volume":"20","author":"Kennedy","year":"2005","journal-title":"Hum Reprod"},{"key":"R35-20251216","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1186\/s12967-020-02566-8","article-title":"Quantitative sensory phenotyping in chronic neuropathic pain patients treated with unilateral L4-dorsal root ganglion stimulation","volume":"18","author":"Kinfe","year":"2020","journal-title":"J Transl Med"},{"key":"R36-20251216","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1097\/j.pain.0000000000002324","article-title":"Chronic nociplastic pain affecting the musculoskeletal system: clinical criteria and grading system","volume":"162","author":"Kosek","year":"2021","journal-title":"PAIN"},{"key":"R37-20251216","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1097\/j.pain.0000000000000507","article-title":"Do we need a third mechanistic descriptor for chronic pain states?","volume":"157","author":"Kosek","year":"2016","journal-title":"PAIN"},{"key":"R38-20251216","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1093\/pm\/pnaa192","article-title":"Reliability and validity of the Boston bedside quantitative sensory testing battery for neuropathic pain","volume":"21","author":"Koulouris","year":"2020","journal-title":"Pain Med"},{"key":"R39-20251216","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1097\/j.pain.0000000000001467","article-title":"Somatosensory profiles in acute herpes zoster and predictors of postherpetic neuralgia","volume":"160","author":"Kramer","year":"2019","journal-title":"PAIN"},{"key":"R40-20251216","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.pain.2010.07.026","article-title":"Reference data for quantitative sensory testing (QST): refined stratification for age and a novel method for statistical comparison of group data","volume":"151","author":"Magerl","year":"2010","journal-title":"PAIN"},{"key":"R41-20251216","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.pain.2010.05.002","article-title":"Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes","volume":"150","author":"Maier","year":"2010","journal-title":"PAIN"},{"key":"R42-20251216","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.pain.2013.12.014","article-title":"Comparison of muscle and joint pressure-pain thresholds in patients with complex regional pain syndrome and upper limb pain of other origin","volume":"155","author":"Mainka","year":"2014","journal-title":"PAIN"},{"key":"R43-20251216","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1090-3801(03)00082-X","article-title":"Pressure pain thresholds of tender point sites in patients with fibromyalgia and in healthy controls","volume":"8","author":"Maquet","year":"2004","journal-title":"Eur J Pain"},{"key":"R44-20251216","first-page":"E703","article-title":"The result of acute induced psychosocial stress on pain sensitivity and modulation in healthy people","volume":"23","author":"Mertens","year":"2020","journal-title":"Pain Physician"},{"key":"R45-20251216","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.eururo.2007.09.019","article-title":"Diagnostic criteria, classification, and nomenclature for painful bladder syndrome\/interstitial cystitis: an ESSIC proposal","volume":"53","author":"van de Merwe","year":"2008","journal-title":"Eur Urol"},{"key":"R46-20251216","first-page":"814","article-title":"Muscle and bone pressure pain threshold and pain tolerance in fibromyalgia patients and controls","volume":"73","author":"Mikkelsson","year":"1992","journal-title":"Arch Phys Med Rehabil"},{"key":"R47-20251216","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1097\/AJP.0000000000000798","article-title":"The relationship between clinical and quantitative measures of pain sensitization in knee osteoarthritis","volume":"36","author":"Moore","year":"2020","journal-title":"Clin J Pain"},{"key":"R48-20251216","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejogrb.2016.07.497","article-title":"Mechanisms of pain in endometriosis","volume":"209","author":"Morotti","year":"2017","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R50-20251216","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.clinph.2013.09.038","article-title":"Sensory correlates of pain in peripheral neuropathies","volume":"125","author":"Ng Wing Tin","year":"2014","journal-title":"Clin Neurophysiol"},{"key":"R51-20251216","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.pain.2014.02.004","article-title":"Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Reference data for the trunk and application in patients with chronic postherpetic neuralgia","volume":"155","author":"Pfau","year":"2014","journal-title":"PAIN"},{"key":"R52-20251216","doi-asserted-by":"crossref","first-page":"e588","DOI":"10.1097\/PR9.0000000000000588","article-title":"Postoperative pain\u2014from mechanisms to treatment","volume":"2","author":"Pogatzki-Zahn","year":"2017","journal-title":"Pain Rep"},{"key":"R53-20251216","doi-asserted-by":"crossref","first-page":"e820","DOI":"10.1097\/PR9.0000000000000820","article-title":"Sensory bedside testing: a simple stratification approach for sensory phenotyping","volume":"5","author":"Reimer","year":"2020","journal-title":"Pain Rep"},{"key":"R54-20251216","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.pain.2006.01.041","article-title":"Quantitative sensory testing in the German research network on neuropathic pain (DFNS): standardized protocol and reference values","volume":"123","author":"Rolke","year":"2006","journal-title":"PAIN"},{"key":"R55-20251216","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1744-8069-7-20","article-title":"Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy","volume":"7","author":"Ruscheweyh","year":"2011","journal-title":"Mol Pain"},{"key":"R56-20251216","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.ejogrb.2021.07.029","article-title":"Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain","volume":"264","author":"Shafrir","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R57-20251216","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1111\/pme.12434","article-title":"Incidence of chronic postsurgical pain (CPSP) after general surgery","volume":"15","author":"Simanski","year":"2014","journal-title":"Pain Med"},{"key":"R58-20251216","article-title":"State-trait anxiety inventory","author":"Spielberger","year":"1971","journal-title":"Prof Psychol"},{"key":"R59-20251216","doi-asserted-by":"crossref","first-page":"e0225849","DOI":"10.1371\/journal.pone.0225849","article-title":"Total sleep deprivation increases pain sensitivity, impairs conditioned pain modulation and facilitates temporal summation of pain in healthy participants","volume":"14","author":"Staffe","year":"2019","journal-title":"PLoS One"},{"key":"R60-20251216","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/AOG.0000000000000663","article-title":"Association of chronic pelvic pain and endometriosis with signs of sensitization and myofascial pain","volume":"125","author":"Stratton","year":"2015","journal-title":"Obstet Gynecol"},{"key":"R61-20251216","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1037\/1040-3590.7.4.524","article-title":"The pain catastrophizing scale: development and validation","volume":"7","author":"Sullivan","year":"1995","journal-title":"Psychol Assess"},{"key":"R62-20251216","first-page":"40","article-title":"Mechanisms of postoperative pain-neuropathic. In: Postoperative Pain Management: An Evidence-Based Guide to Practice","author":"Talbot","year":"2006","journal-title":"Elsevier"},{"key":"R63-20251216","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/j.1532-2149.2012.00227.x","article-title":"Self-reported sensory descriptors are associated with quantitative sensory testing parameters in patients with cervical radiculopathy, but not in patients with fibromyalgia","volume":"17","author":"Tampin","year":"2013","journal-title":"Eur J Pain"},{"key":"R64-20251216","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1080\/03007995.2018.1451313","article-title":"Sensory profiles are comparable in patients with distal and proximal entrapment neuropathies, while the pain experience differs","volume":"34","author":"Tampin","year":"2018","journal-title":"Curr Med Res Opin"},{"key":"R65-20251216","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.pain.2009.05.023","article-title":"Differential involvement of A-delta and A-beta fibres in neuropathic pain related to carpal tunnel syndrome","volume":"145","author":"Truini","year":"2009","journal-title":"PAIN"},{"key":"R66-20251216","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00002060-199809000-00004","article-title":"Experimental pressure pain in patients with complex regional pain syndrome, type I (Reflex sympathetic dystrophy)","volume":"77","author":"Vatine","year":"1998","journal-title":"Am J Phys Med Rehabil"},{"key":"R67-20251216","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1365-2842.2008.01932.x","article-title":"The impact of stress and anxiety on the pressure pain threshold of myofascial pain patients","volume":"36","author":"Vedolin","year":"2009","journal-title":"J Oral Rehabil"},{"key":"R68-20251216","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1097\/j.pain.0000000000000433","article-title":"Quantitative sensory testing using DFNS protocol in Europe: an evaluation of heterogeneity across multiple centers in patients with peripheral neuropathic pain and healthy subjects","volume":"157","author":"Vollert","year":"2016","journal-title":"PAIN"},{"key":"R69-20251216","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1097\/j.pain.0000000000001190","article-title":"Pathophysiological mechanisms of neuropathic pain: Comparison of sensory phenotypes in patients and human surrogate pain models","volume":"159","author":"Vollert","year":"2018","journal-title":"PAIN"},{"key":"R70-20251216","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1097\/j.pain.0000000000000935","article-title":"Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations","volume":"158","author":"Vollert","year":"2017","journal-title":"PAIN"},{"key":"R71-20251216","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1097\/j.pain.0000000000002323","article-title":"Nociplastic pain: helping to explain disconnect between pain and pathology","volume":"162","author":"Walsh","year":"2021","journal-title":"PAIN"},{"key":"R72-20251216","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.jpain.2019.11.013","article-title":"Test-retest and inter-examiner reliability of a novel bedside quantitative sensory testing battery in postherpetic neuralgia patients","volume":"21","author":"Wasan","year":"2020","journal-title":"J Pain"},{"key":"R73-20251216","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s12903-018-0601-8","article-title":"Somatosensory profiles of patients with chronic myogenic temporomandibular disorders in relation to their painDETECT score","volume":"18","author":"Welte-Jzyk","year":"2018","journal-title":"BMC Oral Health"},{"key":"R74-20251216","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s11916-001-0005-2","article-title":"Pelvic pain: a chronic visceral pain syndrome","volume":"5","author":"Wesselmann","year":"2001","journal-title":"Curr Pain Headache Rep"},{"key":"R75-20251216","doi-asserted-by":"crossref","first-page":"e0151950","DOI":"10.1371\/journal.pone.0151950","article-title":"An exploratory study into objective and reported characteristics of neuropathic pain in women with chronic pelvic pain","volume":"11","author":"Whitaker","year":"2016","journal-title":"PLoS One"},{"key":"R76-20251216","doi-asserted-by":"crossref","first-page":"634804","DOI":"10.3389\/fpain.2021.634804","article-title":"Abdominal and pelvic pain: current challenges and future opportunities","volume":"2","author":"Yuan","year":"2021","journal-title":"Front Pain Res (Lausanne)"},{"key":"R77-20251216","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41572-018-0008-5","article-title":"Endometriosis","volume":"4","author":"Zondervan","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"R78-20251216","first-page":"541","article-title":"The community prevalence of chronic pelvic pain in women and associated illness behaviour","volume":"51","author":"Zondervan","year":"2001","journal-title":"Br J Gen Pract"}],"container-title":["Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/j.pain.0000000000002955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T09:00:29Z","timestamp":1765875629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/j.pain.0000000000002955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,7]]},"references-count":77,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.1097\/j.pain.0000000000002955","relation":{},"ISSN":["0304-3959","1872-6623"],"issn-type":[{"value":"0304-3959","type":"print"},{"value":"1872-6623","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,7]]},"assertion":[{"value":"2022-10-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}