{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:46:44Z","timestamp":1758631604587},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9]]},"abstract":"\n Background<\/jats:title>\n Endoscopic stenting proved to be a safe alternative to surgery for malignant intra-abdominal gastrointestinal obstruction. Although high technical success rates have been reported, some patients do not experience relief in symptoms.<\/jats:p>\n <\/jats:sec>\n \n Aim<\/jats:title>\n This study aimed to analyse the factors predicting the effectiveness of stent placement in patients with gastrointestinal obstruction.<\/jats:p>\n <\/jats:sec>\n \n Patients and methods<\/jats:title>\n A retrospective study was carried out including 160 patients who underwent palliative stenting for intra-abdominal obstruction in a tertiary centre from December 2012 to July 2017. Technical and clinical success, stent dysfunction and adverse events were analysed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The rate of technical success was 98%. The rate of early clinical success was 69 and 81% in upper and lower gastrointestinal obstructions, respectively (P<\/jats:italic>=0.107). In the upper tract, obstruction caused by carcinomatosis was the only independent factor predicting early and late clinical failure [odds ratio (OR): 9.7, 95% confidence interval (CI): 2.5\u201338.4, P<\/jats:italic>=0.001 and OR: 7.6, 95% CI: 1.8\u201331.9, P<\/jats:italic>=0.006, respectively]. In the colon, Eastern Cooperative Oncology Group score of at least 3 was an independent factor for early clinical failure (OR: 29.8, 95% CI: 1.9\u2013464.9, P<\/jats:italic>=0.002) and obstruction caused by carcinomatosis was an independent factor for late clinical failure (OR: 14.4, 95% CI: 1.7\u2013119.6, P<\/jats:italic>=0.013). Perforation occurred in 4 patients (2.5%) and stent dysfunction occurred in 15% of patients (4% stent migration; 9% restenosis). Carcinomatosis was a risk factor for perforation (P<\/jats:italic>=0.039) and migration was higher with shorter 6\u2009cm stents (P<\/jats:italic>=0.044).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Stents are effective and safe for palliation of intra-abdominal obstruction. Carcinomatosis predicts an unfavourable clinical outcome. Palliative stenting as an option should be weighed carefully in these patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1097\/meg.0000000000001178","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:43:59Z","timestamp":1527723839000},"page":"1033-1040","source":"Crossref","is-referenced-by-count":16,"title":["Endoscopic stenting for palliation of intra-abdominal gastrointestinal malignant obstruction: predictive factors for clinical success"],"prefix":"10.1097","volume":"30","author":[{"given":"In\u00eas","family":"Pais-Cunha","sequence":"first","affiliation":[{"name":"Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal"}]},{"given":"Rui","family":"Castro","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"}]},{"given":"Diogo","family":"Lib\u00e2nio","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"},{"name":"Center for Research in Health Technologies and Information Systems"}]},{"given":"In\u00eas","family":"Pita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"}]},{"given":"Rui P.","family":"Bastos","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"}]},{"given":"Rui","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"}]},{"given":"Mario","family":"Dinis-Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"},{"name":"Center for Research in Health Technologies and Information Systems"}]},{"given":"Pedro","family":"Pimentel-Nunes","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Portuguese Oncology Institute of Porto"},{"name":"Center for Research in Health Technologies and Information Systems"},{"name":"Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal"}]}],"member":"276","reference":[{"key":"R1-20230916","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3322\/caac.21262","article-title":"Global cancer statistics, 2012","volume":"65","author":"Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"R2-20230916","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.gassur.2003.11.020","article-title":"Palliative therapy of rectal cancer. 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