{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:53:08Z","timestamp":1790783588167,"version":"4.1.0"},"reference-count":40,"publisher":"The Royal Society","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"funder":[{"name":"Mexico's National Council of Science and Technology"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Biol. Lett."],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>\n            The amoebae (and many other protists) have traditionally been considered as asexual organisms, but suspicion has been growing that these organisms are cryptically sexual or are at least related to sexual lineages. This contention is mainly based on genome studies in which the presence of \u2018meiotic genes\u2019 has been discovered. Using RNA-seq (next-generation shotgun sequencing, identifying and quantifying the RNA species in a sample), we have found that the entire repertoire of meiotic genes is expressed in exponentially growing\n            <jats:italic>Acanthamoeba<\/jats:italic>\n            and we argue that these so-called meiotic genes are involved in the related process of homologous recombination in this amoeba. We contend that they are only involved in meiosis in other organisms that indulge in sexual reproduction and that homologous recombination is important in asexual protists as a guard against the accumulation of mutations. We also suggest that asexual reproduction is the ancestral state.\n          <\/jats:p>","DOI":"10.1098\/rsbl.2018.0871","type":"journal-article","created":{"date-parts":[[2019,3,6]],"date-time":"2019-03-06T08:07:01Z","timestamp":1551859621000},"page":"20180871","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":29,"title":["\u2018Meiotic genes\u2019 are constitutively expressed in an asexual amoeba and are not necessarily involved in sexual reproduction"],"prefix":"10.1098","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8234-6061","authenticated-orcid":true,"given":"Sutherland K.","family":"Maciver","sequence":"first","affiliation":[{"name":"Centre for Discovery Brain Sciences, Edinburgh Medical School, Biomedical Sciences, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zisis","family":"Koutsogiannis","sequence":"additional","affiliation":[{"name":"Centre for Discovery Brain Sciences, Edinburgh Medical School, Biomedical Sciences, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"de Obeso Fern\u00e1ndez del Valle","sequence":"additional","affiliation":[{"name":"Centre for Discovery Brain Sciences, Edinburgh Medical School, Biomedical Sciences, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2019,3,6]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2011.0289"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1501725112"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a016154"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.protis.2014.07.008"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/bies.20764"},{"key":"e_1_3_6_7_2","first-page":"185","article-title":"A phylogenomic inventory of meiotic genes; evidence for sex in Giardia and an early eukaryotic origin of meiosis","volume":"15","author":"Ramesh MA","year":"2005","journal-title":"Curr. 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Ethel Waddell Githii Honors Program Theses. BSc Thesis Spelman College Atlanta University. See http:\/\/digitalcommons.auctr.edu\/ewghonors\/3."},{"key":"e_1_3_6_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1992.tb01316.x"},{"key":"e_1_3_6_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2009.11.007"},{"key":"e_1_3_6_41_2","unstructured":"Maciver SK Koutsogiannis Z de Obeso Fern\u00e1ndez del Valle A. 2019 Data from: \u2018Meiotic genes\u2019 are constitutively expressed in an asexual amoeba and are not necessarily involved in sexual reproduction. Dryad Digital Repository . 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