{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T01:33:27Z","timestamp":1772156007215,"version":"3.50.1"},"reference-count":60,"publisher":"The Royal Society","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"name":"UKRI Global Challenges Research Fund"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Biol. Lett."],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>\n                    Mosquitoes are the deadliest vectors of diseases. They impose a huge health burden on human populations spreading parasites as disparate as protozoans (malaria), viruses (yellow fever and more) and nematodes (filariasis) that cause life-threatening conditions. In recent years, mating has been proposed as a putative target for population control. Mosquitoes mate mid-air, in swarms initiated by males and triggered by a combination of internal and external stimuli. As the number of females in a swarm is limited, there is intense competition among males, and they \u2018retune\u2019 their physiology for this demanding behaviour. There is limited knowledge on the \u2018genetic reprogramming\u2019 required to enable swarming. Interestingly, recent evidence indicates that the upregulation of circadian clock genes may be involved in the swarming of malaria mosquitoes of the genus\n                    <jats:italic>Anopheles<\/jats:italic>\n                    . Here, we use whole-head RNA-seq to identify gene expression changes in\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    males that are engaged in swarming in a laboratory setting. Our results suggest that in preparation to swarming, males tend to lower some housekeeping functions while increasing remodelling of the cytoskeleton and neuronal connectivity; the transcription of circadian clock genes is unaffected.\n                  <\/jats:p>","DOI":"10.1098\/rsbl.2024.0245","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T20:06:04Z","timestamp":1730232364000},"update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Molecular correlates of swarming behaviour in\n                    <i>Aedes aegypti<\/i>\n                    males"],"prefix":"10.1098","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1470-2108","authenticated-orcid":true,"given":"Julien","family":"Devilliers","sequence":"first","affiliation":[{"name":"Neurogenetics Group,University of Leicester, Leicester, UK"},{"name":"Department of Genetics,Genomics &amp; Cancer Sciences, College of Life Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1860-780X","authenticated-orcid":true,"given":"Hollie","family":"Marshall","sequence":"additional","affiliation":[{"name":"Neurogenetics Group,University of Leicester, Leicester, UK"},{"name":"Department of Genetics,Genomics &amp; Cancer Sciences, College of Life Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7871-0091","authenticated-orcid":true,"given":"Ben","family":"Warren","sequence":"additional","affiliation":[{"name":"Neurogenetics Group,University of Leicester, Leicester, UK"},{"name":"Department of Genetics,Genomics &amp; Cancer Sciences, College of Life Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4889-7606","authenticated-orcid":true,"given":"Charalambos P.","family":"Kyriacou","sequence":"additional","affiliation":[{"name":"Neurogenetics Group,University of Leicester, Leicester, UK"},{"name":"Department of Genetics,Genomics &amp; Cancer Sciences, College of Life Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5878-1792","authenticated-orcid":true,"given":"Luciana O.","family":"Araripe","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Biologia Molecular de Insetos, Instituto Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7082-9768","authenticated-orcid":true,"given":"Rafaela V.","family":"Bruno","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Biologia Molecular de Insetos, Instituto Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7297-4697","authenticated-orcid":true,"given":"Ezio","family":"Rosato","sequence":"additional","affiliation":[{"name":"Neurogenetics Group,University of Leicester, Leicester, UK"},{"name":"Department of Genetics,Genomics &amp; Cancer Sciences, College of Life Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0857-1732","authenticated-orcid":true,"given":"Roberto","family":"Feuda","sequence":"additional","affiliation":[{"name":"Neurogenetics Group,University of Leicester, Leicester, UK"},{"name":"Department of Genetics,Genomics &amp; Cancer Sciences, College of Life Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"key":"e_1_3_7_2_2","unstructured":"WHO. 2020 Vector-borne diseases"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-015-0961-8"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-ento-011613-162002"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3439"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1410488111"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078884"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2013.12.011"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1948-7134.2012.00230.x"},{"key":"e_1_3_7_10_2","volume-title":"Sensory reception and behaviour","author":"Clements AN","year":"1999","unstructured":"Clements AN. 1999 The biology of mosquitoes. 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