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Lett."],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>\n                    Environmental unpredictability challenges the transmission success of vector-borne parasites like\n                    <jats:italic toggle=\"yes\">Plasmodium<\/jats:italic>\n                    , whose fitness depends on synchronizing the production of transmission forms, called gametocytes, with vector availability. Although mosquito bites are known to trigger\n                    <jats:italic toggle=\"yes\">Plasmodium<\/jats:italic>\n                    responses, it remains unclear whether parasites respond specifically to competent vectors or adopt a generalist strategy. We experimentally infected birds with the avian malaria parasite\n                    <jats:italic toggle=\"yes\">Plasmodium relictum<\/jats:italic>\n                    and exposed them to bites from either a competent (\n                    <jats:italic toggle=\"yes\">Culex quinquefasciatus<\/jats:italic>\n                    ) or a non-competent (\n                    <jats:italic toggle=\"yes\">Anopheles gambiae<\/jats:italic>\n                    ) vector species. Both exposures induced a rise in parasitaemia, but the response was significantly stronger to the non-competent species. Host inflammatory, humoral and stress markers remained similar across mosquito treatments, implying that unidentified physiological cues may underlie the parasite\u2019s response. No species-specific modulation of gametocyte conversion rate or sex ratio was observed. These findings suggest that\n                    <jats:italic toggle=\"yes\">P. relictum<\/jats:italic>\n                    does not discriminate between mosquito species, instead employing a generalist, possibly bet-hedging strategy in response to any mosquito bite. Our results highlight the importance of mosquito community composition in shaping parasite transmission dynamics. If non-vector mosquitoes enhance\n                    <jats:italic toggle=\"yes\">Plasmodium<\/jats:italic>\n                    transmission investment, shifts in vector assemblages due to climate change or control measures may have unanticipated effects on disease ecology.\n                  <\/jats:p>","DOI":"10.1098\/rsbl.2025.0464","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:05:34Z","timestamp":1762301134000},"update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Plastic responses of\n                    <i>Plasmodium relictum<\/i>\n                    to competent and non-competent mosquito bites"],"prefix":"10.1098","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2735-5150","authenticated-orcid":true,"given":"Valentin","family":"Chauvin","sequence":"first","affiliation":[{"name":"MiVEGEC (University of Montpellier, CNRS, IRD)","place":["Montpellier, France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Berthomieu","sequence":"additional","affiliation":[{"name":"MiVEGEC (University of Montpellier, CNRS, IRD)","place":["Montpellier, France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Loiseau","sequence":"additional","affiliation":[{"name":"MiVEGEC (University of Montpellier, CNRS, IRD)","place":["Montpellier, France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7084-1261","authenticated-orcid":true,"given":"Christian","family":"N. Tchana","sequence":"additional","affiliation":[{"name":"MiVEGEC (University of Montpellier, CNRS, IRD)","place":["Montpellier, France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2619-167X","authenticated-orcid":true,"given":"Fr\u00e9d\u00e9ric","family":"Angelier","sequence":"additional","affiliation":[{"name":"Centre d\u2019Etudes Biologiques de Chiz\u00e9, CNRS, La Rochelle Universit\u00e9, UMR7372","place":["Villiers-en-Bois, France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7056-5846","authenticated-orcid":true,"given":"Ana","family":"Rivero","sequence":"additional","affiliation":[{"name":"MiVEGEC (University of Montpellier, CNRS, IRD)","place":["Montpellier, France"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2005.00879.x"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fevo.2021.715381"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-4571.2008.00060.x"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2021.111375"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/284198"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/282461"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1515\/9781400832019"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.156.3774.477"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)92722-X"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2008.08.001"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004308"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2020.2615"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.2006.00805.x"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.48.060402.102812"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006439"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-017-3579-8"},{"key":"e_1_3_8_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-13-614"},{"key":"e_1_3_8_19_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.73080"},{"key":"e_1_3_8_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-34534-9"},{"key":"e_1_3_8_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0276437"},{"key":"e_1_3_8_22_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007806"},{"key":"e_1_3_8_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06954"},{"key":"e_1_3_8_24_2","doi-asserted-by":"publisher","DOI":"10.1645\/0022-3395(2002)088[0258:FIATSR]2.0.CO;2"},{"key":"e_1_3_8_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2018.06.002"},{"key":"e_1_3_8_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-0998.2009.02692.x"},{"key":"e_1_3_8_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(65)90036-6"},{"key":"e_1_3_8_28_2","article-title":"Single cell transcriptomics and development of gametocyte-specific molecular markers for avian malaria parasites","author":"Berthomieu A","year":"2025","unstructured":"Berthomieu A, Gandon S, Talman A, Rivero A. 2025 Single cell transcriptomics and development of gametocyte-specific molecular markers for avian malaria parasites. 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