{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:42:02Z","timestamp":1791420122028,"version":"4.3.3"},"reference-count":54,"publisher":"The Royal Society","issue":"141","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"funder":[{"name":"Strategic Programme (SPR) of the National Institute for Public Health and the Environment","award":["S\/113004\/01\/IP"],"award-info":[{"award-number":["S\/113004\/01\/IP"]}]}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["J. R. Soc. Interface."],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Risk perception plays an important role in testing behaviour for sexually transmitted infections, but is rarely included in mathematical models exploring the impact of testing. We explored the impact of incorporating sexual behaviour (SB), risk perception (RP) and differential testing uptake in SB\u2013RP groups on prevalence, using chlamydia as an example. We developed a pair model with a susceptible\u2013infected\u2013susceptible structure representing heterosexuals aged 16\u201326 years. The effect of testing on chlamydia prevalence was compared between a model with only SB (SB model) and a model with SB and RP (SB\u2013RP model). In the SB\u2013RP model, a scenario without differential testing uptake in SB\u2013RP groups was compared to scenarios with differential testing uptake in SB\u2013RP groups. Introducing testing into the SB\u2013RP model resulted in a slightly smaller reduction in chlamydia prevalence (\u221238.0%) as compared to the SB model (\u221240.4%). In the SB\u2013RP model, the scenario without differential testing uptake in SB\u2013RP groups overestimated the reduction in chlamydia prevalence (with 4.8%), especially in the group with high SB and low RP (19.8%). We conclude that mathematical models incorporating RP and differential testing uptake in SB\u2013RP groups improve the impact assessment of testing and treatment on chlamydia prevalence.<\/jats:p>","DOI":"10.1098\/rsif.2017.0847","type":"journal-article","created":{"date-parts":[[2018,4,4]],"date-time":"2018-04-04T07:25:10Z","timestamp":1522826710000},"page":"20170847","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Double trouble: modelling the impact of low risk perception and high-risk sexual behaviour on chlamydia transmission"],"prefix":"10.1098","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6562-7029","authenticated-orcid":false,"given":"Daphne A.","family":"van Wees","sequence":"first","affiliation":[{"name":"Centre for Infectious Diseases Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"den Daas","sequence":"additional","affiliation":[{"name":"Centre for Infectious Diseases Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands"},{"name":"Department of Interdisciplinary Social Science, Faculty of Social and Behavioural Sciences, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam E. 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