{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:47:28Z","timestamp":1787010448490,"version":"build-2736575974"},"reference-count":57,"publisher":"The Royal Society","issue":"200","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","award":["BB\/L004836\/1"],"award-info":[{"award-number":["BB\/L004836\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["J. R. Soc. Interface."],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>\n                    Brucellosis imposes substantial impacts on livestock production and public health worldwide. A stochastic, age-structured model incorporating herd demographics was developed describing within- and between-herd transmission of\n                    <jats:italic>Brucella abortus<\/jats:italic>\n                    in dairy cattle herds. The model was fitted to data from a cross-sectional study conducted in Punjab State of India and used to evaluate the effectiveness of control strategies under consideration. Based on model results, stakeholder acceptance and constraints regarding vaccine supply, vaccination of replacement calves in large farms should be prioritized. Test and removal applied at early stages of the control programme where seroprevalence is high would not constitute an effective or acceptable use of resources because significant numbers of animals would be \u2018removed\u2019 (culled or not used for breeding) based on false positive results. To achieve sustained reductions in brucellosis, policymakers must commit to maintaining vaccination in the long term, which may eventually reduce frequency of infection in the livestock reservoir to a low enough level for elimination to be a realistic objective. This work provides key strategic insights into the control of brucellosis in India, which has the largest cattle population globally, and a general modelling framework for evaluating control strategies in endemic settings.\n                  <\/jats:p>","DOI":"10.1098\/rsif.2022.0756","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T19:05:21Z","timestamp":1678215921000},"update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Modelling the control of bovine brucellosis in India"],"prefix":"10.1098","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0892-0034","authenticated-orcid":true,"given":"H. R.","family":"Holt","sequence":"first","affiliation":[{"name":"Veterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre in Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield AL9 7TA, UK"},{"name":"Communicable Diseases Policy Research Group, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Walker","sequence":"additional","affiliation":[{"name":"Veterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre in Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield AL9 7TA, UK"},{"name":"London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Beauvais","sequence":"additional","affiliation":[{"name":"Comparative Pathobiology Department, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Veterinary Microbiology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. S.","family":"Bedi","sequence":"additional","affiliation":[{"name":"School of Public Health and Zoonosis, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Mangtani","sequence":"additional","affiliation":[{"name":"Faculty of Epidemiology and Population Health, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. S.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Veterinary Microbiology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. P. S.","family":"Gill","sequence":"additional","affiliation":[{"name":"School of Public Health and Zoonosis, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Godfroid","sequence":"additional","affiliation":[{"name":"Faculty of Biosciences, Fisheries and Economics, Department of Arctic and Marine Biology, UiT \u2013 The Arctic University of Norway, Hansine Hansens veg 18, 9019 Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"McGiven","sequence":"additional","affiliation":[{"name":"WOAH Brucellosis Reference Laboratory, FAO Collaborating Centre for Brucellosis, Department of Bacteriology, Animal &amp; Plant Health Agency, Surrey, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Guitian","sequence":"additional","affiliation":[{"name":"Veterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre in Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield AL9 7TA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2023,3,8]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001929"},{"key":"e_1_3_7_3_2","unstructured":"World Bank. 2011 World livestock disease atlas: a quantitative analysis of global animal health data (2006\u20132009) . 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