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The spiral radius and frequency dependence on force was predicted to follow a universal law, validated by actin\u2013myosin experiments. However, the theory was primarily compared to acto-myosin spirals, assuming no effect of filament length and that motor velocity is additive with density. Here, we reconstitute microtubule spirals driven by dynein transport and end-pinning and find that spiral size scales with force with an exponent \u03b1 approximately \u22121\/3, consistent with theoretical predictions. However, spiral radius scaling with length deviates from the theory and can be explained by a \u2018variable persistence length\u2019 model. The previously predicted exponent of frequency scaling with force \u03b2 approximately 4\/3 is not observed in experiments. A model that assumes constant collective transport velocity of motors regardless of density predicts the scaling exponent \u03b2 approximately 1\/3, comparable to that observed experimentally. Our work demonstrates that microtubule motor systems deviate from the general scaling laws of cytoskeletal spirals predicted previously, based on both detailed mechanics of microtubules and collective force generation of motors.<\/jats:p>","DOI":"10.1098\/rsif.2026.0085","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:07:48Z","timestamp":1789517268000},"source":"Crossref","is-referenced-by-count":0,"title":["Scaling of microtubule spirals driven by dyneins: collective effect of microtubule and motor mechanics"],"prefix":"10.1098","volume":"23","author":[{"given":"Aman","family":"Soni","sequence":"first","affiliation":[{"name":"Biology, Indian Institute of Science Education and Research Pune , Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani A.","family":"Yadav","sequence":"additional","affiliation":[{"name":"Biology, Indian Institute of Science Education and Research Pune , Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9506-2153","authenticated-orcid":false,"given":"Chaitanya A.","family":"Athale","sequence":"additional","affiliation":[{"name":"Biology, Indian Institute of Science Education and Research Pune , Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"2026091520073729200_RSIF20260085C1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1146\/annurev.cellbio.13.1.83","article-title":"Microtubule polymerization dynamics","volume":"13","author":"Desai","year":"1997","journal-title":"Annu. 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