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A key question is how to generate more and healthier progenies by choosing optimal mates. In<jats:italic>Drosophila melanogaster<\/jats:italic>, males use multiple sensory cues, including vision, olfaction and gustation, to achieve reproductive success. These sensory inputs are important, yet not all these different modalities are simultaneously required for courtship behaviour to occur. Moreover, the roles of these sensory inputs for male courtship choice remain largely unknown. Here, we demonstrate that males court younger females with greater preference and that olfactory inputs are indispensable for this male courtship choice. Specifically, the olfactory receptor Or47b is required for males to discriminate younger female mates from older ones. In combination with our previous work indicating that gustatory perception is necessary for this preference behaviour, our current study demonstrates the requirement of both olfaction and gustation in<jats:italic>Drosophila<\/jats:italic>males' courtship preference, thus providing new insights into the role of sensory cues in reproductive behaviour and success.<\/jats:p>","DOI":"10.1098\/rsob.160086","type":"journal-article","created":{"date-parts":[[2016,6,8]],"date-time":"2016-06-08T09:32:17Z","timestamp":1465378337000},"page":"160086","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Or47b plays a role in<i>Drosophila<\/i>males' preference for younger mates"],"prefix":"10.1098","volume":"6","author":[{"given":"Luming","family":"Zhuang","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Disease Research, 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