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About 90% of instances of pancreatic cancer are pancreatic adenocarcinomas. About 10\u201320% of pancreatic carcinomas are resectable and potentially curable, and the 5-year survival rate is only 4%; as a result, the majority of pancreatic cancer treatments are palliative in nature. Surgical resection is the only curative treatment; however, because of late diagnosis, the majority of patients appear at an advanced stage, and only a small percentage (10\u201320%) of them are candidates for surgery. Due to pancreatic cancer\u2019s strong resistance to practically all chemotherapeutic drugs and conventional radiotherapies, conventional radiation and chemotherapies have little effectiveness in extending patients\u2019 overall life. A lot of scientific studies, however, frequently use the metaphorical term \u2018double-edged sword\u2019 to indicate how autophagy plays a different function in cancer. 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