{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:47:45Z","timestamp":1768315665266,"version":"3.49.0"},"reference-count":27,"publisher":"The Royal Society","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"funder":[{"name":"Belgian Programme on Interuniversity Poles of Attraction","award":["IAP 07\/09"],"award-info":[{"award-number":["IAP 07\/09"]}]},{"name":"University of Leuven","award":["GOA 13\/04"],"award-info":[{"award-number":["GOA 13\/04"]}]},{"name":"KU Leuven BOF Centre of Excellence Financing"},{"DOI":"10.13039\/501100001655","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["G. 0637.15"],"award-info":[{"award-number":["G. 0637.15"]}],"id":[{"id":"10.13039\/501100001655","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001655","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["G.0562.11"],"award-info":[{"award-number":["G.0562.11"]}],"id":[{"id":"10.13039\/501100001655","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["R. Soc. open sci."],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p>More than two decades of archaeological research at the site of Sagalassos, in southwest Turkey, resulted in the study of the former urban settlement in all its features. Originally settled in late Classical\/early Hellenistic times, possibly from the later fifth century BCE onwards, the city of Sagalassos and its surrounding territory saw empires come and go. The Plague of Justinian in the sixth century CE, which is considered to have caused the death of up to a third of the population in Anatolia, and an earthquake in the seventh century CE, which is attested to have devastated many monuments in the city, may have severely affected the contemporary Sagalassos community. Human occupation continued, however, and Byzantine Sagalassos was eventually abandoned around 1200 CE. In order to investigate whether these historical events resulted in demographic changes across time, we compared the mitochondrial DNA variation of two population samples from Sagalassos (Roman and Middle Byzantine) and a modern sample from the nearby town of A\u011flasun. Our analyses revealed no genetic discontinuity across two millennia in the region and Bayesian coalescence-based simulations indicated that a major population decline in the area coincided with the final abandonment of Sagalassos, rather than with the Plague of Justinian or the mentioned earthquake.<\/jats:p>","DOI":"10.1098\/rsos.150250","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T10:13:53Z","timestamp":1455704033000},"page":"150250","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Comparing maternal genetic variation across two millennia reveals the demographic history of an ancient human population in southwest Turkey"],"prefix":"10.1098","volume":"3","author":[{"given":"Claudio","family":"Ottoni","sequence":"first","affiliation":[{"name":"Center for Archaeological Sciences, University of Leuven, Leuven, Belgium"},{"name":"Department of Imaging &amp; Pathology, University of Leuven, Leuven, Belgium"},{"name":"Laboratory of Forensic Genetics and Molecular Archaeology, UZ Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4217-3060","authenticated-orcid":false,"given":"Rita","family":"Rasteiro","sequence":"additional","affiliation":[{"name":"Department of Genetics, School of History, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rinse","family":"Willet","sequence":"additional","affiliation":[{"name":"Depatment of Humanities, Institute of History, Leiden University, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Claeys","sequence":"additional","affiliation":[{"name":"Sagalassos Archaeological Research Project, University of Leuven, Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Talloen","sequence":"additional","affiliation":[{"name":"Sagalassos Archaeological Research Project, University of Leuven, Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrien","family":"Van de Vijver","sequence":"additional","affiliation":[{"name":"Center for Archaeological Sciences, University of Leuven, Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loun\u00e8s","family":"Chikhi","sequence":"additional","affiliation":[{"name":"CNRS, Universit\u00e9 Paul Sabatier, ENFA; UMR5174 EDB (Laboratoire \u00c9volution &amp; Diversit\u00e9 Biologique), Toulouse, France"},{"name":"Universit\u00e9 Toulouse 3 Paul Sabatier, CNRS; UMR5174 EDB, Toulouse, France"},{"name":"Instituto Gulbenkian de Ci\u00eancia, Oeiras, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen","family":"Poblome","sequence":"additional","affiliation":[{"name":"Sagalassos Archaeological Research Project, University of Leuven, Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronny","family":"Decorte","sequence":"additional","affiliation":[{"name":"Department of Imaging &amp; Pathology, University of Leuven, Leuven, Belgium"},{"name":"Laboratory of Forensic Genetics and Molecular Archaeology, UZ Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","published-online":{"date-parts":[[2016,2]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1241844"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060944"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055519"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116801"},{"key":"e_1_3_6_6_2","volume-title":"Exempli gratia: Sagalassos, Marc Waelkens and interdisciplinary archaeology","author":"Poblome J","year":"2014"},{"key":"e_1_3_6_7_2","volume-title":"From 8000 BC to 2000 BC: six thousand years of the Burdur\u2013Antalya region","author":"Duru R","year":"2008"},{"key":"e_1_3_6_8_2","first-page":"311","article-title":"Romanization in the East: a case study. Sagalassos and Pisidia (SW Turkey)","volume":"52","author":"Waelkens M.","year":"2002","journal-title":"IstMitt"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0305-4403(02)00204-2"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70323-2"},{"key":"e_1_3_6_11_2","first-page":"5","article-title":"The Justinian Plague","volume":"49","author":"Allen P.","year":"1979","journal-title":"Byzantion"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1144\/GSL.SP.2000.171.01.27"},{"key":"e_1_3_6_13_2","volume-title":"LRCW 4 - archaeology and archaeometry. The Mediterranean","author":"Poblome J","year":"2014"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.2143\/TURC.37.0.2011709"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2010.230"},{"key":"e_1_3_6_16_2","volume-title":"Optimization of methods and procedures for the analysis of mtDNA sequences and their applications in molecular archaeological and historical finds","author":"Jehaes E","year":"1998"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-0998.2010.02847.x"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a026036"},{"key":"e_1_3_6_19_2","first-page":"135","volume-title":"Simulation, genetics and human prehistory","author":"Beaumont M","year":"2008"},{"key":"e_1_3_6_20_2","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1093\/genetics\/162.4.2025","article-title":"Approximate Bayesian computation in population genetics","volume":"162","author":"Beaumont MA","year":"2002","journal-title":"Genetics"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti154"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/jhered\/91.6.506"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2041-210X.2011.00179.x"},{"key":"e_1_3_6_24_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1320811111"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2871"},{"key":"e_1_3_6_26_2","first-page":"507","volume-title":"Sagalassos IV","author":"Poblome J","year":"1997"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1086\/383236"},{"key":"e_1_3_6_28_2","volume-title":"Holocene vegetation history in the territory of Sagalassos, southwest Turkey a palynological approach","author":"Vermoere M","year":"2004"}],"container-title":["Royal Society Open Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsos.150250","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/full-xml\/10.1098\/rsos.150250","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsos.150250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T10:14:01Z","timestamp":1654337641000},"score":1,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsos.150250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1098\/rsos.150250"],"URL":"https:\/\/doi.org\/10.1098\/rsos.150250","relation":{},"ISSN":["2054-5703"],"issn-type":[{"value":"2054-5703","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"2015-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-01-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}