{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T23:42:53Z","timestamp":1788392573885,"version":"build-2803163510"},"reference-count":69,"publisher":"The Royal Society","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"The National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21472106 and 91645120"],"award-info":[{"award-number":["21472106 and 91645120"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["R. Soc. open sci."],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>The development of metal-free organic reactions is one of the hotspots in the synthesis of cyclic compounds. ROTf (alkyl trifluoromethanesulfonates), due to their good electrophilicity, are powerful alkylating reagents at heteroatoms such as nitrogen, oxygen, sulfur and phosphorus to induce an electrophilic centre for carbon\u2013carbon or carbon\u2013heteroatom bond formation. Inspired by this chemistry, a variety of research concentrating on heterocycles synthesis has been carried out. In this review, we mainly summarize the ROTf-induced annulation of heteroatom reagents such as nitriles, carbodiimides, azobenzenes, isothiocyanates, aldehydes, isocyanates and phosphaalkene with themselves or alkynes to afford cyclic compounds.<\/jats:p>","DOI":"10.1098\/rsos.181389","type":"journal-article","created":{"date-parts":[[2018,11,7]],"date-time":"2018-11-07T08:25:59Z","timestamp":1541579159000},"page":"181389","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["ROTf-induced annulation of heteroatom reagents and unsaturated substrates leading to cyclic compounds"],"prefix":"10.1098","volume":"5","author":[{"given":"Song","family":"Zou","sequence":"first","affiliation":[{"name":"MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Wang","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9602-7309","authenticated-orcid":true,"given":"Chanjuan","family":"Xi","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, People's Republic of China"},{"name":"State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2018,11,7]]},"reference":[{"key":"e_1_3_6_2_2","volume-title":"Palladium in heterocyclic chemistry","author":"Lie JJ","year":"2000"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr020085h"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr020095i"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr0683966"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr078361l"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr050041j"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804348105"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201102984"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja207296y"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja2087085"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol201439t"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol301912a"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr400274j"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol501207w"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b02994"},{"key":"e_1_3_6_17_2","volume-title":"Methyltrifluoromethanesulfonate. 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