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Soc. open sci."],"published-print":{"date-parts":[[2019,9,27]]},"abstract":"<jats:p>Sensitive and selective assays are demanded for quantitation of new psychoactive substances such as 4-chloroethcathinone that is a \u03c0-conjugated keto compound. Carbon dots (C-dots) prepared from L-arginine through a hydrothermal route have been used for quantitation of 4-chloroethcathinone in aqueous solution and on C-dot-functionalized papers (CDFPs). To prepare CDFPs, chromatography papers, each with a pattern of 8 \u00d7 12 circles (wells), are first fabricated through a solid-ink printing method and then the C-dots are coated into the wells. \u03c0-Conjugated keto or ester compounds induce photoluminescence quenching of C-dots through an electron transfer process. At pH 7.0, the CDFPs allow screening of abused drugs such as cocaine, heroin and cathinones. Because of poor solubility of heroin and cocaine at pH 11.0, the C-dot probe is selective for cathinones. 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