{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:15:14Z","timestamp":1791386114503,"version":"4.3.3"},"reference-count":64,"publisher":"The Royal Society","issue":"10","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["R. Soc. open sci."],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>\n            Feeding pets raw meat-based diets (RMBDs) has become increasingly popular but may constitute a risk due to the contamination with pathogenic and antimicrobial-resistant (AMR) bacteria. The aim of this study was to evaluate commercially available RMBDs with regard to microbiological quality and occurrence of AMR Enterobacteriaceae. Of 51 RMBD samples, 72.5% did not meet the microbiological standards for Enterobacteriaceae set out by EU regulations for animal by-products intended for pet food. Furthermore,\n            <jats:italic>Salmonella<\/jats:italic>\n            was detected in 3.9% of the samples. AMR bacteria were found in 62.7% of the samples, the majority thereof were resistant to third-generation cephalosporins due to the production of extended-spectrum \u03b2-lactamases (ESBLs) including CTX-M-1, which is widespread in livestock, and CTX-M-15, which is the most common ESBL variant worldwide. Colistin- and aminoglycoside-resistant isolates, producing MCR-1 and RMTB, were identified in 3.9 and 2% of the samples, respectively. The majority of the AMR\n            <jats:italic>Escherichia coli<\/jats:italic>\n            belonged to commensal groups A or B1 and were associated with clonal complexes CC155 and CC10. Two belonged to the emerging extraintestinal pathogenic CC648, and one to the globally disseminated uropathogenic\n            <jats:italic>E. coli<\/jats:italic>\n            sequence type ST69, suggesting zoonotic potential. The microbiological quality and the high prevalence of AMR producing Enterobacteriaceae in RMBDs raise concerns for animal and public health.\n          <\/jats:p>","DOI":"10.1098\/rsos.191170","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T07:09:52Z","timestamp":1571209792000},"page":"191170","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":79,"title":["Raw meat-based diets for companion animals: a potential source of transmission of pathogenic and antimicrobial-resistant Enterobacteriaceae"],"prefix":"10.1098","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3242-9739","authenticated-orcid":true,"given":"Magdalena","family":"N\u00fcesch-Inderbinen","sequence":"first","affiliation":[{"name":"Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Treier","sequence":"additional","affiliation":[{"name":"Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Zurfluh","sequence":"additional","affiliation":[{"name":"Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1002-4762","authenticated-orcid":true,"given":"Roger","family":"Stephan","sequence":"additional","affiliation":[{"name":"Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.11.1549"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114511002765"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.105199"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.104535"},{"key":"e_1_3_6_6_2","first-page":"513","article-title":"Bacteriological evaluation of commercial canine and feline raw diets","volume":"46","author":"Weese JS","year":"2005","journal-title":"Can. 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