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Soc. open sci."],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>\n                    Enterobacterales of clinical importance for humans and domestic animals are now commonly detected among wildlife worldwide. However, few studies have investigated their prevalence among bats, particularly in bat species living near humans. In this study, we assessed the occurrence of Extended-spectrum beta-lactamase-producing (ESBL) and carbapenemase-resistant (CR) Enterobacterales in rectal swabs of bats submitted to the Chilean national rabies surveillance program from 2021 to 2022. From the 307 swabs screened, 47 (15%) harboured cefotaxime-resistant Enterobacterales. Bats carrying these bacteria originated from 9 out of the 14 Chilean regions. Most positive samples were obtained from\n                    <jats:italic>Tadarida brasiliensis<\/jats:italic>\n                    (\n                    <jats:italic>n<\/jats:italic>\n                    = 42), but also\n                    <jats:italic>Lasiurus varius<\/jats:italic>\n                    ,\n                    <jats:italic>L. cinereus<\/jats:italic>\n                    and\n                    <jats:italic>Histiotus macrotus<\/jats:italic>\n                    . No Enterobacterales were resistant to imipenem. All ESBL-Enterobacterales were confirmed as\n                    <jats:italic>Rahnella aquatilis<\/jats:italic>\n                    by MALDI-TOF. No other ESBL or CR Enterobacterales were detected. To our knowledge, this is the first screening of antibiotic-resistant bacteria in wild bats of Chile, showing the bat faecal carriage of\n                    <jats:italic>R. aquatilis<\/jats:italic>\n                    naturally resistant to cephalosporins, but also including acquired resistance to important antibiotics for public health such as amoxicillin with clavulanic acid. Our results suggest unknown selective pressures on\n                    <jats:italic>R. aquatilis<\/jats:italic>\n                    , but low or no carriage of ESBL or CR\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Klebsiella<\/jats:italic>\n                    spp. Future studies should assess the zoonotic and environmental implications of\n                    <jats:italic>R. aquatilis<\/jats:italic>\n                    , which are likely present in the guano left by bats roosting in human infrastructures.\n                  <\/jats:p>","DOI":"10.1098\/rsos.231177","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T19:06:28Z","timestamp":1699383988000},"update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Detection of antimicrobial-resistant Enterobacterales in insectivorous bats from Chile"],"prefix":"10.1098","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1030-3876","authenticated-orcid":true,"given":"Zulma Esperanza","family":"Rojas-Sereno","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n para la Sustentabilidad y Doctorado en Medicina de la Conservaci\u00f3n \/Facultad Ciencias de la Vida, Universidad Andr\u00e9s Bello, Rep\u00fablica 440, Santiago 8320000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7475-2705","authenticated-orcid":true,"given":"Daniel G.","family":"Streicker","sequence":"additional","affiliation":[{"name":"School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G12 8QQ, UK"},{"name":"MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Suarez-Yana","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n para la Sustentabilidad y Doctorado en Medicina de la Conservaci\u00f3n \/Facultad Ciencias de la Vida, Universidad Andr\u00e9s Bello, Rep\u00fablica 440, Santiago 8320000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Lineros","sequence":"additional","affiliation":[{"name":"Secci\u00f3n Rabia, Departamento Laboratorio Biom\u00e9dico, Instituto de Salud P\u00fablica de Chile, Santiago 8320000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"Yung","sequence":"additional","affiliation":[{"name":"Secci\u00f3n Rabia, Departamento Laboratorio Biom\u00e9dico, Instituto de Salud P\u00fablica de Chile, Santiago 8320000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Godreuil","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, Centre Hospitalier Universitaire de Montpellier, Montpellier 34295, France"},{"name":"Laboratoire Mixte International, DRISA, IRD, Montpellier 34394, France"},{"name":"MIVEGEC, IRD, CNRS, Universit\u00e9 de Montpellier, Montpellier 34394, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3920-9165","authenticated-orcid":false,"given":"Julio A.","family":"Benavides","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n para la Sustentabilidad y Doctorado en Medicina de la Conservaci\u00f3n \/Facultad Ciencias de la Vida, Universidad Andr\u00e9s Bello, Rep\u00fablica 440, Santiago 8320000, Chile"},{"name":"MIVEGEC, IRD, CNRS, Universit\u00e9 de Montpellier, Montpellier 34394, 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