{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:06:56Z","timestamp":1773292016680,"version":"3.50.1"},"reference-count":30,"publisher":"The Royal Society","issue":"1131","license":[{"start":{"date-parts":[[1977,8,22]],"date-time":"1977-08-22T00:00:00Z","timestamp":241056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1977,8,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A study of two isolates of Leishmania braziliensis braziliensis in the hindgut of experimentally infected Lutzomyia longipalpis was made with the light and electron microscopes. Infections were always heavier in the pylorus than the ileum, and no parasites were found in the rectum. The parasites became attached to the cuticular intima lining the hindgut by hemidesmosomes formed within the sheath of the flagellum. In parts of the ileum where the lining was in folds, attachment was additionally by the insertion of greatly enlarged flagella which became moulded to fit the folds; large folds were filled with masses of parasites. In both the pylorus and ileum, the parasites were promastigotes, sphaeromastigotes or paramastigotes with a juxtanuclear kinetoplast. Dividing stages were common. It is thought that the unique development of the braziliensis complex in the pylorus and ileum of the sandfly is simply the preliminary establishment of an infection where the parasites initially multiply before migrating forwards to the foregut and proboscis; it is comparable to the establishment of infection in the midgut by other mammalian leishmaniae.<\/jats:p>","DOI":"10.1098\/rspb.1977.0093","type":"journal-article","created":{"date-parts":[[2006,12,18]],"date-time":"2006-12-18T18:11:46Z","timestamp":1166465506000},"page":"191-199","source":"Crossref","is-referenced-by-count":29,"title":["<i>Leishmania<\/i>\n                    in phlebotomid sandflies V. The nature and significance of infections of the pylorus and ileum of the sandfly by leishmaniae of the\n                    <i>braziliensis<\/i>\n                    complex"],"prefix":"10.1098","volume":"198","author":[{"given":"R.","family":"Killick-Kendrick","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. H.","family":"Molyneux","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hommel","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. J.","family":"Leaney","sequence":"additional","affiliation":[{"name":"Department of Zoology and Applied Entomology, Imperial College, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. S.","family":"Robertson","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","reference":[{"key":"p_1","first-page":"553","article-title":"Reptiles and their importance in the epidemiology of leishmaniasis","volume":"44","author":"Belova E. M.","year":"1971","journal-title":"Bull. WldHlth Org."},{"key":"p_2","unstructured":"Brack C. 1968 Elektronenmikroskopische Untersuchungen zum Lebenszyklus von Trypanosoma cruzi. Unter besonderer Beriicksichtigung der Entwickhingsformen im Dbertrager Rhodnius prolixus. Acta trop. 25 289."},{"key":"p_3","doi-asserted-by":"crossref","unstructured":"Brooker B. E. 1970 Desmosomes and hemidesmosomes in the flagellate Crithidiafasciculata. Z. Zellforsch. mikrosk.Anat. 105 155-166.","DOI":"10.1007\/BF00335467"},{"key":"p_4","unstructured":"Bran R. 1974 Ultrastruktur und Zylus von Herpetosoma ` mirabilis ' und Crithidia luciliaein Chrysomyia chloropyga. Acta trop. 31 219-290."},{"key":"p_5","unstructured":"Chance M. L. Gardener P. J. & Peters W. 1977 The biochemical taxonomy of Leishmania as an ecological tool. Bull. C.N.R.S. (In the Press.)"},{"key":"p_6","first-page":"177","article-title":"Desenvolvimento de esp 6cies do genero Leishmania em esp^cies brazileiras de flebbtomos do genero Fran\u00a7a, 1924. I. Evolu\u00a7ao de L. braziliensis em flebbtomos","volume":"9","author":"Coelho M.","year":"1967","journal-title":"Sdo Paulo"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(63)90014-6"},{"key":"p_8","first-page":"9","article-title":"Leishmania braziliensis braziliensis in immunosuppressed hamsters and nude mice. Trans. R. Soc. trop","volume":"69","author":"Hommel M.","year":"1975","journal-title":"Med. Hyg."},{"key":"p_9","first-page":"53","article-title":"The differentiation of Herpetomonas megaseliae: ultrastructural observations","volume":"21","author":"Janovy J.","year":"1974","journal-title":"J ."},{"key":"p_10","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(70)90033-0"},{"key":"p_11","doi-asserted-by":"publisher","DOI":"10.2307\/3275439"},{"key":"p_12","first-page":"429","article-title":"The establishment, maintenance and productivity of a laboratory colony of Lutzomyia longipalpis (Diptera: Psychodidae). J . med","volume":"13","author":"Killick-Kendrick R.","year":"1976","journal-title":"Ent."},{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1977.0032"},{"key":"p_14","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1974.0085"},{"key":"p_15","unstructured":"Killick-Kendrick R. Molyneux D. H. Leaney A. J. & Rioux J.-A. 1977 Aspects of the life-cycle of Leishmania in the sandfly. Proc. 2nd europ. Multicoil. Parasit. Trogir 1975. (In the Press.)"},{"key":"p_16","doi-asserted-by":"crossref","unstructured":"Lainson R. & Shaw J. J. 1971 Epidemiological considerations of the leishmanias with particular reference to the New World. In Ecology and physiology of parasites (ed. A. M. Fallis) pp. 21-56. London: Hilger.","DOI":"10.3138\/9781487595128-004"},{"key":"p_17","first-page":"44","article-title":"Leishmaniasis of the New World; taxonomic problems. Br. med","volume":"28","author":"Lainson R.","year":"1972","journal-title":"Bull."},{"key":"p_18","first-page":"1","article-title":"Leishmanias and leishmaniasis of the New World, with particular reference to","volume":"7","author":"Lainson R.","year":"1973","journal-title":"Brazil. Bull. Pan Am. Hlth Org."},{"key":"p_19","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(73)90143-0"},{"key":"p_20","unstructured":"Lainson R. Ward R. 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