{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T04:08:17Z","timestamp":1767499697663,"version":"3.48.0"},"reference-count":19,"publisher":"The Royal Society","issue":"1165","license":[{"start":{"date-parts":[[1980,1,17]],"date-time":"1980-01-17T00:00:00Z","timestamp":316915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980,1,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Reproduction in the Japanese quail (Coturnix coturnix japonica) as in many other species, is controlled by the length of the daily photoperiod. The present experiments have investigated the neuroendocrine regulation of both the photoperiodically induced \u2018tonic\u2019 gonadotrophin secretion, which causes the development and maintenance of the ovary, and the \u2018cyclic\u2019 surge release of luteinizing hormone (LH), which stimulates ovulation. Areas within the anterior and tuberal hypothalamus were destroyed by means of electrolytic lesions while a small knife was used to isolate, to various degrees, the tuberal hypothalamus. Information was obtained on the regulation of \u2018tonic\u2019 and \u2018cyclic\u2019 secretion of gonado\u00adtrophin by using immature and mature laying females, respectively. The results indicate that the neuroendocrine regulation of photo\u00adperiodically induced gonadotrophin secretion in immature quail appears to be controlled by two discrete hypothalamic centres, the infundibular nuclear complex (i. n. c.) and the preoptic region (po. r.). The supraoptic region (so. r.) appears to have no influence on photoperiodically induced ovarian development. Deafferentation reveals that afferents from the anterior hypothalamus enter the tuberal region in a diffuse manner from both anterior and lateral directions. As in the developing animals, destruction of either the i. n. c. or the po. r. in mature birds results in a complete block to \u2018tonic\u2019 gonadotrophin release and to regression of the ovaries. When the supraoptic region is destroyed, the \u2018cyclic\u2019 ovulatory surge of LH is blocked and a polyfollicular syndrome ensues in which the ovaries, still under the influence of \u2018tonic\u2019 gonadotrophin release, grow to a very large size, but no ovulation takes place. An intramuscular injection of progesterone stimulates a release of LH in both untreated mature females and in sham-operated females, but not in so. r. -lesioned birds. Priming these lesioned females with oestrogen and progesterone restores, in some birds, the ability to respond positively to progesterone stimulation.<\/jats:p>","DOI":"10.1098\/rspb.1980.0006","type":"journal-article","created":{"date-parts":[[2006,12,15]],"date-time":"2006-12-15T17:06:33Z","timestamp":1166202393000},"page":"421-437","source":"Crossref","is-referenced-by-count":11,"title":["The neuroendocrine control of gonadotrophin release in the Japanese quail. III. The role of the tuberal and anterior hypothalamus in the control of ovarian development and ovulation"],"prefix":"10.1098","volume":"206","author":[{"given":"D. T.","family":"Davies","sequence":"first","affiliation":[{"name":"Department of Zoology, University College of North Wales, Bangor LL59 2UW, Gwynedd, U. K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James Munro","family":"Dodd","sequence":"additional","affiliation":[{"name":"Department of Zoology, University College of North Wales, Bangor LL59 2UW, Gwynedd, U. K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","reference":[{"key":"p_1","unstructured":"Bayle J.-D. Bouille C. & Oliver J. 1975 Repercussions de rhemispherectomie sur les reflexes neuroendocriniens chez les Oiseaux. 1501-1504."},{"key":"p_2","unstructured":"hebd. Sdanc. Acad. Sci. Paris D 281"},{"key":"p_3","doi-asserted-by":"crossref","unstructured":"Bons N. 1976 Retinohypothalamic pathway in the duck (Anas Res. 168 343-360. . Cell Tissue","DOI":"10.1007\/BF00215312"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1007\/BF00220517"},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.1159\/000122120"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1977.0098"},{"key":"p_7","unstructured":"Critchlow V. 1963 The role of light in the neuroendocrine system. In Advances in Neuroendocrinology (ed. A. V. Nalbandov) pp. 377-402. Urbana: University of Illinois Press."},{"key":"p_8","first-page":"68","article-title":"Neuroendocrine regulation ol ovarian development and ovulation in the Japanese quail. Gen. comp","volume":"34","author":"Davies D. T.","year":"1978","journal-title":"Endocrinol."},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1975.0129"},{"key":"p_10","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1975.0130"},{"key":"p_11","first-page":"346","article-title":"Endocrine effects of diencephalic lesions in the white leghorn hen. Gen. comp","volume":"3","author":"Egge A. S.","year":"1963","journal-title":"Endocrinol."},{"key":"p_12","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0710051"},{"key":"p_13","first-page":"357","article-title":"The plasma concentrations of testosterone and LH during the ovulation cycle of the hen. Acta endocr","volume":"84","author":"Etches R. J.","year":"1977","journal-title":"Copenh."},{"key":"p_14","first-page":"3","article-title":"The timing of ovulation. J","volume":"75","author":"Everett J. W.","year":"1977","journal-title":"Endocr."},{"key":"p_15","first-page":"117","article-title":"Photoperiodic control in the secretion of gonadotrophins in birds","author":"Famer D. S.","year":"1975","journal-title":"Am. Zool. 15 (suppl.)"},{"key":"p_16","doi-asserted-by":"crossref","unstructured":"Follett B. K. 1978 Photoperiodism and seasonal breeding in birds and mammals. In Control of ovulation (ed. D. B. Crighton N. B. Haynes G. R. Foxcroft & G. E. Lamming) pp. 267-293. London: Butterworths.","DOI":"10.1016\/B978-0-408-70924-8.50021-9"},{"key":"p_17","unstructured":"Follett B. K. & Davies D. T. 1979 The endocrine control of ovulation in birds. In Proc. BeltsvilleAgricultural Center Symp. I I I . Animal Reproduction (ed. H. W. Hawk)."},{"key":"p_18","unstructured":"Montclair New Jersey: Allenheld Osmun & Co. (in press)."},{"key":"p_19","doi-asserted-by":"crossref","unstructured":"Follett B. K. Davies D. T. & Magee V. 1975 The rate of testicular development in Japanese quail following stimulation of the extra-retinal photoreceptor. 31 48-50.","DOI":"10.1007\/BF01924673"}],"container-title":["Proceedings of the Royal Society of London. Series B. Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rspb.1980.0006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/rspb\/article-pdf\/206\/1165\/421\/172047\/rspb.1980.0006.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/royalsocietypublishing.org\/rspb\/article-pdf\/206\/1165\/421\/172047\/rspb.1980.0006.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T04:05:03Z","timestamp":1767499503000},"score":1,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/rspb\/article\/206\/1165\/421\/33169\/The-neuroendocrine-control-of-gonadotrophin"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1,17]]},"references-count":19,"journal-issue":{"issue":"1165","published-print":{"date-parts":[[1980,1,17]]}},"URL":"https:\/\/doi.org\/10.1098\/rspb.1980.0006","relation":{},"ISSN":["0080-4649","2053-9193"],"issn-type":[{"type":"print","value":"0080-4649"},{"type":"electronic","value":"2053-9193"}],"subject":[],"published":{"date-parts":[[1980,1,17]]}}}