{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:00:01Z","timestamp":1791180001254,"version":"4.1.0"},"reference-count":41,"publisher":"The Royal Society","issue":"1786","license":[{"start":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T00:00:00Z","timestamp":1404691200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Proc. R. Soc. B."],"published-print":{"date-parts":[[2014,7,7]]},"abstract":"<jats:p>\n            For organisms with complex life cycles, larval environments can modify adult phenotypes. For mosquitoes and other vectors, when physiological impacts of stressors acting on larvae carry over into the adult stage they may interact with infectious dose of a vector-borne pathogen, producing a range of phenotypes for vector potential. Investigation of impacts of a common source of stress, larval crowding and intraspecific competition, on adult vector interactions with pathogens may increase our understanding of the dynamics of pathogen transmission by mosquito vectors. Using\n            <jats:italic>Aedes aegypti<\/jats:italic>\n            and the nematode parasite\n            <jats:italic>Brugia pahangi<\/jats:italic>\n            , we demonstrate dose dependency of fitness effects of\n            <jats:italic>B. pahangi<\/jats:italic>\n            infection on the mosquito, as well as interactions between competitive stress among larvae and infectious dose for resulting adults that affect the physiological and functional ability of mosquitoes to act as vectors. Contrary to results from studies on mosquito\u2013arbovirus interactions, our results suggest that adults from crowded larvae may limit infection better than do adults from uncrowded controls, and that mosquitoes from high-quality larval environments are more physiologically and functionally capable vectors of\n            <jats:italic>B. pahangi<\/jats:italic>\n            . Our results provide another example of how the larval environment can have profound effects on vector potential of resulting adults.\n          <\/jats:p>","DOI":"10.1098\/rspb.2014.0459","type":"journal-article","created":{"date-parts":[[2014,5,14]],"date-time":"2014-05-14T09:33:28Z","timestamp":1400060008000},"page":"20140459","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["What does not kill them makes them stronger: larval environment and infectious dose alter mosquito potential to transmit filarial worms"],"prefix":"10.1098","volume":"281","author":[{"given":"Jennifer A.","family":"Breaux","sequence":"first","affiliation":[{"name":"School of Biological Sciences, Illinois State University, Normal, IL 61790-4120, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly K.","family":"Schumacher","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Illinois State University, Normal, IL 61790-4120, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Juliano","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Illinois State University, Normal, IL 61790-4120, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2014,7,7]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1994.0012"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-228"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.2307\/3283951"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.48.091801.112722"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2008.02.008"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2006.3483"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.54.110807.090611"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2005.00755.x"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10530-007-9188-8"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2007.1497"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1890\/05-0209"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/35.5.825"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585-39.1.162"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2012.01.001"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2915.2011.00993.x"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/35.2.157"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ecolsys.32.081501.114006"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1603\/022.038.0206"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.1.338"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/eva.12048"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.54.110807.090626"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000529"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000666"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1974.11686973"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4922(01)01927-4"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1993.49.756"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2012.1394"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(75)90031-4"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.3920\/978-90-8686-744-8_4"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2013.0711"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762003000200009"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004420050833"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2006.0630"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-261"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2011.09.001"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00008099"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.1973.11.1.33"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(82)90170-5"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761999000500005"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2000.0984"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1910(85)90036-8"}],"container-title":["Proceedings of the Royal Society B: Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rspb.2014.0459","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/full-xml\/10.1098\/rspb.2014.0459","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rspb.2014.0459","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T12:37:10Z","timestamp":1613565430000},"score":1,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rspb.2014.0459"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,7]]},"references-count":41,"journal-issue":{"issue":"1786","published-print":{"date-parts":[[2014,7,7]]}},"alternative-id":["10.1098\/rspb.2014.0459"],"URL":"https:\/\/doi.org\/10.1098\/rspb.2014.0459","relation":{},"ISSN":["0962-8452","1471-2954"],"issn-type":[{"value":"0962-8452","type":"print"},{"value":"1471-2954","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,7]]},"assertion":[{"value":"2014-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-04-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-07-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}