{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:58:46Z","timestamp":1790233126093,"version":"4.1.0"},"reference-count":45,"publisher":"The Royal Society","issue":"1870","license":[{"start":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T00:00:00Z","timestamp":1515542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Proc. R. Soc. B."],"published-print":{"date-parts":[[2018,1,10]]},"abstract":"<jats:p>Where disease threatens endangered wildlife populations, substantial resources are required for management actions such as vaccination. While network models provide a promising tool for identifying key spreaders and prioritizing efforts to maximize efficiency, population-scale vaccination remains rare, providing few opportunities to evaluate performance of model-informed strategies under realistic scenarios. Because the endangered Hawaiian monk seal could be heavily impacted by disease threats such as morbillivirus, we implemented a prophylactic vaccination programme. We used contact networks to prioritize vaccinating animals with high contact rates. We used dynamic network models to simulate morbillivirus outbreaks under real and idealized vaccination scenarios. We then evaluated the efficacy of model recommendations in this real-world vaccination project. We found that deviating from the model recommendations decreased the efficiency; requiring 44% more vaccinations to achieve a given decrease in outbreak size. However, we gained protection more quickly by vaccinating available animals rather than waiting to encounter priority seals. This work demonstrates the value of network models, but also makes trade-offs clear. If vaccines were limited but time was ample, vaccinating only priority animals would maximize herd protection. However, where time is the limiting factor, vaccinating additional lower-priority animals could more quickly protect the population.<\/jats:p>","DOI":"10.1098\/rspb.2017.1899","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T10:13:23Z","timestamp":1515579203000},"page":"20171899","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals"],"prefix":"10.1098","volume":"285","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0539-0306","authenticated-orcid":false,"given":"Stacie J.","family":"Robinson","sequence":"first","affiliation":[{"name":"NOAA National Marine Fisheries Service, Pacific Islands Fisheries Science Center, 1845 Wasp Boulevard, Honolulu, HI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle M.","family":"Barbieri","sequence":"additional","affiliation":[{"name":"NOAA National Marine Fisheries Service, Pacific Islands Fisheries Science Center, 1845 Wasp Boulevard, Honolulu, HI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Murphy","sequence":"additional","affiliation":[{"name":"University of Washington, Seattle, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D.","family":"Baker","sequence":"additional","affiliation":[{"name":"NOAA National Marine Fisheries Service, Pacific Islands Fisheries Science Center, 1845 Wasp Boulevard, Honolulu, HI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert L.","family":"Harting","sequence":"additional","affiliation":[{"name":"Harting Biological Consulting, Bozeman, MT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meggan E.","family":"Craft","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, University of Minnesota, St Paul, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles L.","family":"Littnan","sequence":"additional","affiliation":[{"name":"NOAA National Marine Fisheries Service, Pacific Islands Fisheries Science Center, 1845 Wasp Boulevard, Honolulu, HI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2018,1,10]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2004.00693.x"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1739.2006.00524.x"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1890\/140241"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/1365-2664.12084"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.physa.2010.02.034"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2014.0349"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature01343"},{"key":"e_1_3_7_9_2","first-page":"41","volume-title":"Pacific marine mammal stock assessments: 2016","author":"Baker J","year":"2016"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jhered\/esn077"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10393-006-0059-z"},{"key":"e_1_3_7_12_2","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1748-7692.2012.00616.x","article-title":"A Longman's beaked whale (Indopacetus pacificus) strands in Maui, Hawaii, with first case of morbillivirus in the central Pacific","volume":"29","author":"West KL","year":"2013","journal-title":"Mar. Mamm. Sci."},{"key":"e_1_3_7_13_2","first-page":"125","article-title":"Morbilliviruses and morbillivirus diseases of marine mammals","volume":"4","author":"de Swart R","year":"1995","journal-title":"Infect. Agents Dis."},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb04350.x"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/42163"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.3390\/v6125093"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10393-012-0783-5"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05177"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0440"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2012.0139"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.7589\/2012-06-156"},{"key":"e_1_3_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2006.10.005"},{"key":"e_1_3_7_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature04324"},{"key":"e_1_3_7_24_2","doi-asserted-by":"publisher","DOI":"10.7589\/2016-10-238"},{"key":"e_1_3_7_25_2","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/676949"},{"key":"e_1_3_7_26_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2014.0107"},{"key":"e_1_3_7_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/brv.12236"},{"key":"e_1_3_7_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/biosci\/biw175"},{"key":"e_1_3_7_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwi308"},{"key":"e_1_3_7_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005016"},{"key":"e_1_3_7_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2009.01370.x"},{"key":"e_1_3_7_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.epidem.2014.07.003"},{"key":"e_1_3_7_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/mms.12084"},{"key":"e_1_3_7_34_2","unstructured":"Csardi G Nepusz T. 2006 The igraph software package for complex network research. InterJournal Complex Systems e1695."},{"key":"e_1_3_7_35_2","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2013"},{"key":"e_1_3_7_36_2","doi-asserted-by":"crossref","unstructured":"Jenness SM Goodreau SM Morris M. 2017 EpiModel: an AR package for mathematical modeling of infectious disease over networks. bioRxiv 213009.","DOI":"10.1101\/213009"},{"key":"e_1_3_7_37_2","doi-asserted-by":"publisher","DOI":"10.1890\/13-0907.1"},{"key":"e_1_3_7_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2007.02.024"},{"key":"e_1_3_7_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.socnet.2005.07.002"},{"key":"e_1_3_7_40_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1194694"},{"key":"e_1_3_7_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1739.2009.01429.x"},{"key":"e_1_3_7_42_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10980-013-9919-4"},{"key":"e_1_3_7_43_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1508.081061"},{"key":"e_1_3_7_44_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.785"},{"key":"e_1_3_7_45_2","doi-asserted-by":"publisher","DOI":"10.1638\/2008-0080.1"},{"key":"e_1_3_7_46_2","doi-asserted-by":"crossref","first-page":"833","DOI":"10.2460\/ajvr.1997.58.08.833","article-title":"Protection of dogs against canine distemper by vaccination with a canarypox virus recombinant expressing canine distemper virus fusion and hemagglutinin glycoproteins","volume":"58","author":"Pardo M","year":"1997","journal-title":"Am. J. Vet. Res."}],"container-title":["Proceedings of the Royal Society B: Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rspb.2017.1899","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/full-xml\/10.1098\/rspb.2017.1899","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rspb.2017.1899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T11:42:17Z","timestamp":1719747737000},"score":1,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rspb.2017.1899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,10]]},"references-count":45,"journal-issue":{"issue":"1870","published-print":{"date-parts":[[2018,1,10]]}},"alternative-id":["10.1098\/rspb.2017.1899"],"URL":"https:\/\/doi.org\/10.1098\/rspb.2017.1899","relation":{},"ISSN":["0962-8452","1471-2954"],"issn-type":[{"value":"0962-8452","type":"print"},{"value":"1471-2954","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,10]]},"assertion":[{"value":"2017-08-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-12-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}