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R. Soc. B."],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>\n                    Competitors and predators of hosts can alter transmission dynamics within host\u2013parasite systems. Biocontrol aims to harness these effects to mitigate disease, but these attempts may backfire without an understanding of the ecological interactions involved. We investigated how resource competition among snail species affects transmission potential of the human flatworm parasite\n                    <jats:italic toggle=\"yes\">Schistosoma mansoni<\/jats:italic>\n                    from its snail intermediate host,\n                    <jats:italic toggle=\"yes\">Biomphalaria glabrata<\/jats:italic>\n                    . We created experimental communities with\n                    <jats:italic toggle=\"yes\">B. glabrata<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">S. mansoni<\/jats:italic>\n                    and differing compositions of non-host competitor snails\n                    <jats:italic toggle=\"yes\">Melanoides tuberculata<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Physella acuta<\/jats:italic>\n                    . We tracked resource availability, host abundance, size, reproduction and parasite production of cercariae, the schistosome life stage infectious to humans, over 16 weeks. We found that\n                    <jats:italic toggle=\"yes\">Melanoides<\/jats:italic>\n                    acted as a typical resource competitor of\n                    <jats:italic toggle=\"yes\">Biomphalaria,<\/jats:italic>\n                    reducing host body size and per capita cercarial production.\n                    <jats:italic toggle=\"yes\">Physella<\/jats:italic>\n                    , however, reduced host abundance but increased resource availability and cercarial production. In follow-up experiments, we determined that\n                    <jats:italic toggle=\"yes\">Physella<\/jats:italic>\n                    is a voracious consumer of host eggs. We then built a model representing this intraguild predation effect, which was able to explain these initially counterintuitive results. These divergent results from two putative resource competitors of\n                    <jats:italic toggle=\"yes\">Biomphalaria<\/jats:italic>\n                    underscore the importance of establishing the mechanisms through which hosts, non-hosts and parasites interact, especially in the context of biocontrol.\n                  <\/jats:p>","DOI":"10.1098\/rspb.2025.0852","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T23:06:09Z","timestamp":1753225569000},"update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraguild predation among snails drives human schistosome amplification despite susceptible host regulation"],"prefix":"10.1098","volume":"292","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1297-8367","authenticated-orcid":true,"given":"Kelsey E.","family":"Shaw","sequence":"first","affiliation":[{"name":"Department of Biology, Emory University","place":["Atlanta, USA"]},{"name":"University of Notre Dame","place":["Notre Dame, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Hartman","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raeyan","family":"Syed","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Mangabat","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8394-6288","authenticated-orcid":true,"given":"David James","family":"Civitello","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","published-online":{"date-parts":[[2025,7,23]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1506279112"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09575"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1890\/13-1041.1"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/ele.12479"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41559-019-1060-6"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/1365-2435.13892"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2006.00885.x"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1461-0248.2003.00500.x"},{"key":"e_1_3_8_10_2","volume-title":"WHO guideline on control and elimination of human schistosomiasis","author":"World Health Organization","year":"2022","unstructured":"World Health Organization. 2022 WHO guideline on control and elimination of human schistosomiasis. 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