{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:28:27Z","timestamp":1787099307187,"version":"build-2736575974"},"reference-count":78,"publisher":"The Royal Society","issue":"2077","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Spanish Government projects ADAPTIVE"},{"name":"FEDER Una manera de hacer Europa"},{"name":"ENVIOME"},{"DOI":"10.13039\/100000001","name":"National Science Foundation NSF-EPSCoR","doi-asserted-by":"publisher","award":["OIA-1946352"],"award-info":[{"award-number":["OIA-1946352"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011011","name":"Junta de Andaluc\u00eda Postdoctoral","doi-asserted-by":"publisher","award":["DGP_POST_2024_01016"],"award-info":[{"award-number":["DGP_POST_2024_01016"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]},{"name":"MICIU","award":["FPU-2019-01593"],"award-info":[{"award-number":["FPU-2019-01593"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Genomic regions of reduced recombination can preserve linkage among co-adapted alleles, facilitating local adaptation despite high connectivity. Such regions\u2014often generated by chromosomal inversions\u2014may be especially important in highly dispersive marine taxa yet remain poorly documented in echinoderms. Here, we combined a chromosome-level reference genome with genome-wide ddRAD-seq from 296 Marthasterias glacialis individuals across 19 Atlantic\u2013Mediterranean locations to quantify population structure and scan for recombination-suppressed haploblocks. Genome-wide neutral markers showed significant population differentiation together with evidence of high connectivity, revealed by the presence of inter-ecoregion migrants. Additionally, we identified 16 polymorphic haploblocks with patterns consistent with putative chromosomal inversions spanning 18.6% of the genome. Haploblock haplotypes were strongly environmentally and geographically structured and contained genes with key functions in stress response, osmoregulation and thermal tolerance. Haplotype distributions also paralleled previously described mitochondrial lineages despite nuclear gene flow, consistent with a model of ancient divergence followed by secondary contact. Overall, our results suggest a role for widespread structural polymorphism in adaptive differentiation in Echinodermata, providing a framework for linking echinoderm genome rearrangements to ecological divergence. Marthasterias glacialis thus emerges as a promising system to explore how structural variation contributes to adaptation and genome evolution in highly dispersive organisms.<\/jats:p>","DOI":"10.1098\/rspb.2026.0791","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:14:07Z","timestamp":1787098447000},"source":"Crossref","is-referenced-by-count":0,"title":["Hidden genomic structure and widespread structural polymorphism across environmental gradients in the spiny sea star\n                    <i>Marthasterias glacialis<\/i>"],"prefix":"10.1098","volume":"293","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2366-7660","authenticated-orcid":false,"given":"Marta","family":"Mart\u00edn-Huete","sequence":"first","affiliation":[{"name":"Departament de Biologia Evolutiva, Ecologia i Ci\u00e8ncies Ambientals, Universitat de Barcelona (UB) 1 , Av. Diagonal 645, Barcelona 08028, Spain"},{"name":"Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona (UB) 2 , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2419-2516","authenticated-orcid":false,"given":"Aurora","family":"Garc\u00eda-Berro","sequence":"additional","affiliation":[{"name":"Institut Bot\u00e0nic de Barcelona (IBB), CSIC-CMCNB Barcelona 3 , 08038 Catalunya, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2607-7818","authenticated-orcid":false,"given":"Claire","family":"M\u00e9rot","sequence":"additional","affiliation":[{"name":"CNRS, UMR 6553 ECOBIO, Universit\u00e9 de Rennes 4 , Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3697-6526","authenticated-orcid":false,"given":"Roc\u00edo","family":"P\u00e9rez-Portela","sequence":"additional","affiliation":[{"name":"Departament de Biologia Evolutiva, Ecologia i Ci\u00e8ncies Ambientals, Universitat de Barcelona (UB) 1 , Av. Diagonal 645, Barcelona 08028, Spain"},{"name":"Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona (UB) 2 , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4398-329X","authenticated-orcid":false,"given":"Carlos","family":"Leiva","sequence":"additional","affiliation":[{"name":"University of Guam Marine Laboratory 5 , Mangilao, Guam, USA"},{"name":"Estaci\u00f3n Biol\u00f3gica de Do\u00f1ana (EBD-CSIC) 6 , Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"2026081820140170600_RSPB20260791C1","doi-asserted-by":"crossref","first-page":"33269","DOI":"10.1038\/srep33269","article-title":"Low genetic diversity and recent demographic expansion in the red starfish Echinaster sepositus (Retzius 1816)","volume":"6","author":"Garcia-Cisneros","year":"2016","journal-title":"Sci. Rep."},{"key":"2026081820140170600_RSPB20260791C2","doi-asserted-by":"crossref","first-page":"32425","DOI":"10.1038\/srep32425","article-title":"Contrasted phylogeographic patterns on mitochondrial DNA of shallow and deep brittle stars across the Atlantic-Mediterranean area","volume":"6","author":"Taboada","year":"2016","journal-title":"Sci. Rep."},{"key":"2026081820140170600_RSPB20260791C3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/s41437-018-0098-6","article-title":"Spatio-temporal patterns of genetic variation in Arbacia lixula, a thermophilous sea urchin in expansion in the Mediterranean","volume":"122","author":"P\u00e9rez-Portela","year":"2019","journal-title":"Heredity"},{"key":"2026081820140170600_RSPB20260791C4","doi-asserted-by":"crossref","first-page":"12349","DOI":"10.1038\/s41598-023-39584-7","article-title":"Exceptional population genomic homogeneity in the black brittle star Ophiocomina nigra (Ophiuroidea, Echinodermata) along the Atlantic-Mediterranean coast","volume":"13","author":"Leiva","year":"2023","journal-title":"Sci. Rep."},{"key":"2026081820140170600_RSPB20260791C5","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1126\/science.3576198","article-title":"Gene flow and the geographic structure of natural populations","volume":"236","author":"Slatkin","year":"1987","journal-title":"Science"},{"key":"2026081820140170600_RSPB20260791C6","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1111\/mec.14944","article-title":"Chromosomal inversions associated with environmental adaptation in honeybees","volume":"28","author":"Christmas","year":"2019","journal-title":"Mol. Ecol."},{"key":"2026081820140170600_RSPB20260791C7","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1111\/mec.14972","article-title":"Multiple chromosomal rearrangements in a hybrid zone between Littorina saxatilis ecotypes","volume":"28","author":"Faria","year":"2019","journal-title":"Mol. Ecol."},{"key":"2026081820140170600_RSPB20260791C8","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1093\/molbev\/msab143","article-title":"Locally adaptive inversions modulate genetic variation at different geographic scales in a seaweed fly","volume":"38","author":"M\u00e9rot","year":"2021","journal-title":"Mol. Biol. Evol."},{"key":"2026081820140170600_RSPB20260791C9","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1111\/jeb.13047","article-title":"Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow","volume":"30","author":"Ravinet","year":"2017","journal-title":"J. Evol. Biol."},{"key":"2026081820140170600_RSPB20260791C10","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1098\/rstb.2011.0249","article-title":"Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice","volume":"367","author":"Nachman","year":"2012","journal-title":"Phil. Trans. R. Soc. 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