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A."],"published-print":{"date-parts":[[2020,3,6]]},"abstract":"<jats:p>\n                    As noted in Wikipedia,\n                    <jats:italic>skin in the game<\/jats:italic>\n                    refers to having \u2018incurred risk by being involved in achieving a goal\u2019, where \u2018\n                    <jats:italic>skin<\/jats:italic>\n                    is a synecdoche for the person involved, and\n                    <jats:italic>game<\/jats:italic>\n                    is the metaphor for actions on the field of play under discussion\u2019. For exascale applications under development in the US Department of Energy Exascale Computing Project, nothing could be more apt, with the\n                    <jats:italic>skin<\/jats:italic>\n                    being exascale applications and the\n                    <jats:italic>game<\/jats:italic>\n                    being delivering comprehensive science-based computational applications that effectively exploit exascale high-performance computing technologies to provide breakthrough modelling and simulation and data science solutions. These solutions will yield high-confidence insights and answers to the most critical problems and challenges for the USA in scientific discovery, national security, energy assurance, economic competitiveness and advanced healthcare.\n                  <\/jats:p>\n                  <jats:p>This article is part of a discussion meeting issue \u2018Numerical algorithms for high-performance computational science\u2019.<\/jats:p>","DOI":"10.1098\/rsta.2019.0056","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T03:05:47Z","timestamp":1579489547000},"page":"20190056","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":81,"title":["Exascale applications: skin in the game"],"prefix":"10.1098","volume":"378","author":[{"given":"Francis","family":"Alexander","sequence":"first","affiliation":[{"name":"Brookhaven National Laboratory, Upton, NY, 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