{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T04:21:20Z","timestamp":1783657280131,"version":"3.55.0"},"reference-count":11,"publisher":"The Royal Society","issue":"1357","license":[{"start":{"date-parts":[[1997,8,29]],"date-time":"1997-08-29T00:00:00Z","timestamp":872812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phil. Trans. R. Soc. Lond. B"],"published-print":{"date-parts":[[1997,8,29]]},"abstract":"<jats:p>The range of genetic diversity within human populations is enormous. Genetic susceptibility to common chronic disease is a significant part of this genetic diversity, which also includes a variety of rare, clear\u2013cut, inherited diseases. Modern DNA\u2013based genomic analysis can now routinely lead to the identification of genes involved in disease susceptibility, provides the basis for genetic counselling in affected families, and can be used more widely for a genetically targeted approach to disease prevention. This naturally raises problems concerning the use of information not just in an individulal's decisions, but also for employment, and health and life insurance.<\/jats:p>","DOI":"10.1098\/rstb.1997.0083","type":"journal-article","created":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T13:23:02Z","timestamp":1033478582000},"page":"1045-1050","source":"Crossref","is-referenced-by-count":7,"title":["Genetic diversity and disease susceptibility"],"prefix":"10.1098","volume":"352","author":[{"given":"Walter F.","family":"Bodmer","sequence":"first","affiliation":[{"name":"Imperial Cancer Research Fund, Cancer and Immunogenetics Laboratory, Institute of Molecular Medicine, University of OxfordJohn Radcliffe Hospital, Headington, Oxford OX3 9DSUK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[1997,8,29]]},"reference":[{"key":"p_1","first-page":"37","article-title":"The genetics of Celtic populations","volume":"82","author":"Bodmer W. F.","year":"1992","journal-title":"Proc. Br. Acad."},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a072907"},{"key":"p_3","unstructured":"Bodmer W. F. & Cavalli-Sforza L. L. 1976 Genetics e~olution and man. San Francisco : W. H. Freeman & Co."},{"key":"p_4","unstructured":"Bodmer W. F. & McKie R. 1994 ~he book of man. ~he quest to disco~er our genetic heritage. London : Little Brown & Co."},{"key":"p_5","unstructured":"Cavalli-Sforza L. L. Menozzi P. etal 1994 ~he histor~ and geograph~ of human genes. Princeton University Press."},{"key":"p_6","first-page":"321","article-title":"Molecular genetic basis of colorectal cancer susceptibility. Br. ~","volume":"83","author":"Cunningham C.","year":"1996","journal-title":"Surg."},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1136\/ard.35.3.267"},{"key":"p_8","unstructured":"House of Commons Science and Technology Committee. (Session 1994-95.) Human genetics : the science and its consequences. Volume 1."},{"key":"p_9","unstructured":"Stringer C. & McKie R. 1996 African exodus. London : Jonathan Cape."},{"key":"p_10","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/4.suppl_1.1811"},{"key":"p_11","doi-asserted-by":"crossref","unstructured":"Tomlinson I. P. M. & Bodmer W. F. 1995. The HLA system and the analysis of multifactorial genetic disease. ~rends Genet. 11 493-498.","DOI":"10.1016\/S0168-9525(00)89159-3"}],"container-title":["Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstb.1997.0083","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstb.1997.0083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:26:53Z","timestamp":1778621213000},"score":1,"resource":{"primary":{"URL":"http:\/\/royalsocietypublishing.org\/rstb\/article\/352\/1357\/1045-1050\/19085"}},"subtitle":[],"editor":[{"given":"R. M.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[1997,8,29]]},"references-count":11,"journal-issue":{"issue":"1357","published-print":{"date-parts":[[1997,8,29]]}},"alternative-id":["10.1098\/rstb.1997.0083"],"URL":"https:\/\/doi.org\/10.1098\/rstb.1997.0083","relation":{},"ISSN":["0962-8436","1471-2970"],"issn-type":[{"value":"0962-8436","type":"print"},{"value":"1471-2970","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8,29]]}}}