{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:15:02Z","timestamp":1778624102491,"version":"3.51.4"},"reference-count":11,"publisher":"The Royal Society","issue":"1401","license":[{"start":{"date-parts":[[2000,9,29]],"date-time":"2000-09-29T00:00:00Z","timestamp":970185600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phil. Trans. R. Soc. Lond. B"],"published-print":{"date-parts":[[2000,9,29]]},"abstract":"<jats:p>\n                    The olfactory organs from the squid\n                    <jats:italic>Lolliguncula brevis<\/jats:italic>\n                    are composed of a pseudostratified epithelium containing five morphological subtypes of chemosensory neurons and ciliated support cells. Physiological recordings have been made from two of the subtypes and only the type 4 neuron has been studied in detail. Odour\u2013stimulated increases in intracellular calcium and rapid activation of an electrogenic Na\n                    <jats:sup>+<\/jats:sup>\n                    \/Ca\n                    <jats:sup>2+<\/jats:sup>\n                    exchanger current in type 4 neurons suggest that the exchanger proteins are localized very close to the transduction machinery. Electrophysiological studies have shown that olfactory signal transduction takes place in the apical ciliary regions of olfactory neurons. Using polyclonal antiserum against squid Na\n                    <jats:sup>+<\/jats:sup>\n                    \/Ca\n                    <jats:sup>2+<\/jats:sup>\n                    proteins, we observed specific staining in the ciliary region of cells that resemble type 2, 3, 4 and 5 neurons. Staining was also observed in axon bundles, and in muscle tissue. Collectively, these data support the model that Na\n                    <jats:sup>+<\/jats:sup>\n                    \/Ca\n                    <jats:sup>2+<\/jats:sup>\n                    exchanger proteins are localized to transduction machinery in cilia of type 4 neurons and suggest that the other olfactory subtypes also use Ca\n                    <jats:sup>2+<\/jats:sup>\n                    during chemosensory responses.\n                  <\/jats:p>","DOI":"10.1098\/rstb.2000.0670","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T19:55:43Z","timestamp":1027713343000},"page":"1215-1218","source":"Crossref","is-referenced-by-count":15,"title":["Immunohistochemical evidence for the Na\n                    <sup>+<\/sup>\n                    \/Ca\n                    <sup>2+<\/sup>\n                    exchanger in squid olfactory neurons"],"prefix":"10.1098","volume":"355","author":[{"given":"Mary T.","family":"Lucero","sequence":"first","affiliation":[{"name":"Department of Physiology, School of Medicine, University of Utah, Room 155, 410 Chipeta Way, Salt Lake City, UT 84108\u20131297, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Physiology, School of Medicine, University of Utah, Room 155, 410 Chipeta Way, Salt Lake City, UT 84108\u20131297, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Physiology, School of Medicine, University of Utah, Room 155, 410 Chipeta Way, Salt Lake City, UT 84108\u20131297, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"175","published-online":{"date-parts":[[2000,9,29]]},"reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-0981(98)00187-7"},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003590050306"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.115.6.759"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1007\/s003590050007"},{"key":"p_5","doi-asserted-by":"crossref","unstructured":"Emery D. G. 1975 The histology and \u00a2ne structure of the olfactory organ of the squid Lolliguncula brevis Blainville. Tissue Cell 7 357^367.","DOI":"10.1016\/0040-8166(75)90011-7"},{"key":"p_6","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.162.1.209","article-title":"Behavioral responses to chemical stimulation of the olfactory organ in the squid Loligo opalescens","volume":"162","author":"Gilly W. F.","year":"1992","journal-title":"J. Exp. Biol."},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.111.6.857"},{"key":"p_8","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.200.11.1571","article-title":"Characterization of voltageand Ca2+-activated K+ channels in squid olfactory receptor neurons","volume":"200","author":"Lucero M. T.","year":"1997","journal-title":"J. Exp. Biol."},{"key":"p_9","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.162.1.231","article-title":"Electrical responses to chemical stimulation of squid olfactory receptor cells","volume":"162","author":"Lucero M. T.","year":"1992","journal-title":"J. Exp. Biol."},{"key":"p_10","doi-asserted-by":"crossref","unstructured":"Noe J. Tareilus E. Boekho\u00a1 I. & Breer H. 1997 Sodium\/ calcium exchanger in rat olfactory neurons. Neurochem. Int. 30 523^531.","DOI":"10.1016\/S0197-0186(96)00090-3"},{"key":"p_11","doi-asserted-by":"crossref","unstructured":"Piper D. R. & Lucero M. T. 1999 Calcium signalling in squid olfactory receptor neurons. Biol. Signals Recept. 8 329^337.","DOI":"10.1159\/000014606"}],"container-title":["Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstb.2000.0670","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstb.2000.0670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:21:10Z","timestamp":1778620870000},"score":1,"resource":{"primary":{"URL":"http:\/\/royalsocietypublishing.org\/rstb\/article\/355\/1401\/1215-1218\/19813"}},"subtitle":[],"editor":[{"given":"S.P.","family":"Collin","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"N.J.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2000,9,29]]},"references-count":11,"journal-issue":{"issue":"1401","published-print":{"date-parts":[[2000,9,29]]}},"alternative-id":["10.1098\/rstb.2000.0670"],"URL":"https:\/\/doi.org\/10.1098\/rstb.2000.0670","relation":{},"ISSN":["0962-8436","1471-2970"],"issn-type":[{"value":"0962-8436","type":"print"},{"value":"1471-2970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,9,29]]}}}